| 1. |
- Gopalakrishnan, Shyam, et al.
(författare)
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The population genomic legacy of the second plague pandemic
- 2022
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Ingår i: Current Biology. - : Elsevier. - 0960-9822 .- 1879-0445. ; 32:21, s. 4743-4751.e6
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Tidskriftsartikel (refereegranskat)abstract
- Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned for over 300 years, with typical village and town mortality estimated at 10%–40%.1 It is assumed that this high mortality affected the gene pools of these populations. First, local population crashes reduced genetic diversity. Second, a change in frequency is expected for sequence variants that may have affected survival or susceptibility to the etiologic agent (Yersinia pestis).2 Third, mass mortality might alter the local gene pools through its impact on subsequent migration patterns. We explored these factors using the Norwegian city of Trondheim as a model, by sequencing 54 genomes spanning three time periods: (1) prior to the plague striking Trondheim in 1,349 CE, (2) the 17th–19th century, and (3) the present. We find that the pandemic period shaped the gene pool by reducing long distance immigration, in particular from the British Isles, and inducing a bottleneck that reduced genetic diversity. Although we also observe an excess of large FST values at multiple loci in the genome, these are shaped by reference biases introduced by mapping our relatively low genome coverage degraded DNA to the reference genome. This implies that attempts to detect selection using ancient DNA (aDNA) datasets that vary by read length and depth of sequencing coverage may be particularly challenging until methods have been developed to account for the impact of differential reference bias on test statistics.
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| 2. |
- Lundström, Ulf, 1953-
(författare)
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Bebyggelsenamnen i Bureå, Burträsks och Lövångers socknar i Skellefteå kommun jämte studier av huvudleder och nybyggesnamn
- 2015
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis deals with place-names in the southern part of the municipality of Skellefteå in the province of Västerbotten, more precisely the parishes of Bureå, Burträsk and Lövånger. It consists of three different sections, first a survey of the settlement names in each parish, then a section on the second elements in these place-names, and finally a study of names of more recent settlements.The earliest place-names here are names like Blacke, Bureå, Bäck, Kräkånger and Lövånger. The second elements in the names from the medieval expansion period are mark, böle, byn, träsk, sjön and vattnet. Placenames of Nordic, Sami and Finnish origin are found in Skellefteå. The name Lossmen has its origin in Ume Sami and was then borrowed into Finnish. Originally Sami names are Gorkuträsk, Jäppnästjärnliden, Lubboträsk, Sittuträsk and Tavträskliden.The thesis consists of interpretations of the names on parishes, villages, farms and summer pastures, and in Bureå and Lövånger also the names of seasonal fishing stations.The second major section deals with the second elements included in village names, alternative village names, names of parts of villages and farm names. Here the second elements in place-names in Bureå, Burträsk and Lövånger are accounted for, as are the names in the parishes of Byske, Jörn and Skellefteå. This is followed by a discussion of the second elements in Västerbotten and quite often in other parts of Norrland as well.The third major section consists of an analysis of the names of recent settlements in the area. These were established from the 1730s and up to 1870. Founding settlements was a way of providing livelihoods for a rapidly growing population. The study comprises 726 names, of which 269 are in the primary area of investigation, the parishes of Bureå, Burträsk and Lövånger. Extensive comparisons are made continually with conditions in the parishes of Byske, Jörn and Skellefteå in the northern area. The aim of the study is to determine in greater detail what characterises the names of more recent settlements in the municipality of Skellefteå in terms of categories of settlement names, their frequency and distribution within the area. A comparison is also made between Skellefteå and the municipality of Vännäs (Hagervall 1986). One of Hagervall’s findings is that many names are not based on existing features. This thesis shows, however, hardly any cases of stereotype naming in Västerbotten and that in nearly all cases the names refer to features.
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| 3. |
- Margaryan, Ashot, et al.
(författare)
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Population genomics of the Viking world
- 2020
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 585:7825, s. 390-396
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Tidskriftsartikel (refereegranskat)abstract
- The maritime expansion of Scandinavian populations during the Viking Age (about ad750–1050) was a far-flung transformation in world history1,2. Here we sequenced the genomes of 442humans from archaeological sites across Europe and Greenland (to a median depth of about 1×) to understand the global influence of this expansion. We find the Viking period involved gene flow into Scandinavia from the south and east. We observe genetic structure within Scandinavia, with diversity hotspots in the south and restricted gene flow within Scandinavia. We find evidence for a major influx of Danish ancestry into England; a Swedish influx into the Baltic; and Norwegian influx into Ireland, Iceland and Greenland. Additionally, we see substantial ancestry from elsewhere in Europe entering Scandinavia during the Viking Age. Our ancient DNA analysis also revealed that a Viking expedition included close family members. By comparing with modern populations, we find that pigmentation-associated loci have undergone strong population differentiation during the past millennium, and trace positively selected loci—including the lactase-persistence allele of LCT and alleles of ANKA that are associated with the immune response—in detail. We conclude that the Viking diaspora was characterized by substantial transregional engagement: distinct populations influenced the genomic makeup of different regions of Europe, and Scandinavia experienced increased contact with the rest of the continent.
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