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Sökning: WFRF:(Måneheim A.)

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1.
  • Johnson, L., et al. (författare)
  • DIAGNOSTIC RELIABILITY OF MEASUREMENT OF PREMATURE VENTRICULAR COMPLEX FREQUENCY RELATED TO DURATION OF AMBULATORY MONITORING
  • 2021
  • Ingår i: Journal of the American College of Cardiology. - 1558-3597. ; 77:18, Suppl 1, s. 361-361
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Background Premature ventricular complexes (PVCs) are generally quantified using a 24h ECG recording, but the diagnostic accuracy is unknown. We aimed to determine the day-to-day variability and optimal monitoring duration for PVC measurements among patients with frequent PVCs. Methods We included all patients who underwent a clinical ambulatory ECG recording lasting 25-30 days, using the PocketECG device (Medi-Lynx, USA) during 2017, who did not have atrial fibrillation, and in whom ≥1000 PVCs were registered during one of the monitored days. All arrhythmias were manually verified. PVC variability was calculated as the percentage of the mean daily PVC count after full recording. Results The study population consisted of 1,376 individuals (median age 76.0 years, 53% men). Figure 1a shows the population distribution of the mean daily PVC counts. The mean daily PVC count was 2780 (standard deviation: 1556, range 0 - 56,262). A single-day PVC count differed by 69% from the mean daily count. After 18 days the obtained mean PVC count differed
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2.
  • Måneheim, Alexandra, et al. (författare)
  • Diagnostic reliability of monitoring for premature atrial and ventricular complexes
  • 2024
  • Ingår i: Europace. - 1099-5129. ; 26:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims Short-term ambulatory electrocardiogram (ECG) monitoring is often used to assess premature atrial complex (PAC) and premature ventricular complex (PVC) frequency, but the diagnostic reliability is unknown. The objective of this study was to study the day-to-day variability of PAC and PVC frequency. Methods We used 14-day full-disclosure mobile cardiac telemetry recordings without atrial fibrillation in 8245 US patients aged and results 17-103 years to calculate the diagnostic reliability of shorter ambulatory ECG recordings compared with 14-day averages. Over 14 days, 1853 patients had ≥500 PACs/day, 410 patients had ≥5000 PACs/day, and 197 patients had ≥10 000 PACs/day; 1640 patients had ≥500 PVCs/day, 354 patients had ≥5000 PVCs/day, and 175 patients had ≥10 000 PVCs/day. After 3 days, the estimated daily PAC frequency differed by ≥50% from the 14-day mean in 25% of patients; for PVCs, the corresponding duration was 7 days. Ten days of monitoring were needed to estimate PAC and PVC frequency within ±20% of the overall 14-day frequency in 80% of patients. For daily PAC and PVC frequencies ≥10 000, single-day estimation had a specificity of 99.3% [95% confidence interval (CI) 99.1-99.5] at a sensitivity of 76.6 (95% CI 70.1-80.4%) for PACs and a 99.6% (95% CI 99.4-99.7%) specificity at 79.4 (95% CI 72.7-85.2) sensitivity for PVCs. After 7 days, the sensitivity increased to 88.8% (95% CI 83.6-92.9) for PACs and 86.9% (95% CI 80.9-91.5%) for PVCs. Conclusion While there is substantial daily variability across most PAC and PVC levels, findings of ≥10 000 PACs or PVCs are highly specific and do not need to be confirmed with longer recordings.
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