| 1. |
- Zhang, Li, et al.
(författare)
-
Characterization of anti-BCG benz[α]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomycete Nocardia sp. XJ31
- 2020
-
Ingår i: Applied Microbiology and Biotechnology. - : Springer Science and Business Media LLC. - 0175-7598 .- 1432-0614. ; 104:19, s. 8267-8278
-
Tidskriftsartikel (refereegranskat)abstract
- The current global demand for novel anti-TB drugs has drawn urgent attention on the discovery of natural product compounds with anti-TB activity. Lots of efforts have emphasized on environmental samples from unexplored or underexplored natural habits and identified numerous rare actinomycete taxa producing structurally diverse bioactive natural products. Herein, we report a survey of the rare actinobacteria diversity in Xinjiang region together with the discovery of anti-TB active natural products from these strains. We have collected 17 soil samples at different sites with different environmental conditions, from which 39 rare actinobacteria were identified by using a selective isolation strategy with 5 media variations. Among those isolated strains, XJ31 was identified as a new Nocardia sp. based on 16S rRNA gene analysis. Through one strain-many compounds (OSMAC) strategy combined with anti-Bacillus Calmette-Guérin bioassay-guided isolation, two groups of compounds were identified. They were twelve siderophores (nocardimicins, 1-12) and two anthraquinones (brasiliquinones, 13 and 14) and ten of them were identified as new compounds. The structures of the purified compounds were elucidated using HR-ESI-MS, 1D NMR, and 2D NMR techniques. The anti-TB bioassays revealed that the two benz[α]anthraquinones have potent activity against BCG (MICs = 25 μM), which can be used as a promising start point for further anti-TB drug development.
|
|
| 2. |
- Jiang, Xiaoqing, et al.
(författare)
-
A solution-processable copper(II) phthalocyanine derivative as a dopant-free hole-transporting material for efficient and stable carbon counter electrode-based perovskite solar cells
- 2017
-
Ingår i: Journal of Materials Chemistry A. - : Royal Society of Chemistry. - 2050-7488 .- 2050-7496. ; 5:34, s. 17862-17866
-
Tidskriftsartikel (refereegranskat)abstract
- A solution-processable copper(II) phthalocyanine derivative coded as CuPc-TIPS has been synthesized and adopted as a hole-transporting material (HTM) in perovskite solar cells (PSCs), in combination with a mixed-ion perovskite absorber and a low-cost carbon cathode. Optimised PSC devices based on pristine CuPc-TIPS without any additives or dopants show a decent power conversion efficiency of 14.0% (measured at 100 mW cm(-2) illumination, AM 1.5G), together with a good long-termstability under ambient conditions. The present finding highlights the potential of solution-processed copper phthalocyanine derivative-based HTMs for the development of efficient and stable PSCs in the future.
|
|
| 3. |
- Jiang, Xiaoqing, et al.
(författare)
-
Molecular Engineering of Copper Phthalocyanines : A Strategy in Developing Dopant-Free Hole-Transporting Materials for Efficient and Ambient-Stable Perovskite Solar Cells
- 2019
-
Ingår i: Advanced Energy Materials. - : WILEY-V C H VERLAG GMBH. - 1614-6832 .- 1614-6840. ; 9:4
-
Tidskriftsartikel (refereegranskat)abstract
- Copper (II) phthalocyanines (CuPcs) have attracted growing interest as promising hole-transporting materials (HTMs) in perovskite solar cells (PSCs) due to their low-cost and excellent stability. However, the most efficient PSCs using CuPc-based HTMs reported thus far still rely on hygroscopic p-type dopants, which notoriously deteriorate device stability. Herein, two new CuPc derivatives are designed, namely CuPc-Bu and CuPc-OBu, by molecular engineering of the non-peripheral substituents of the Pc rings, and applied as dopant-free HTMs in PSCs. Remarkably, a small structural change from butyl groups to butoxy groups in the substituents of the Pc rings significantly influences the molecular ordering and effectively improves the hole mobility and solar cell performance. As a consequence, PSCs based on dopant-free CuPc-OBu as HTMs deliver an impressive power conversion efficiency (PCE) of up to 17.6% under one sun illumination, which is considerably higher than that of devices with CuPc-Bu (14.3%). Moreover, PSCs containing dopant-free CuPc-OBu HTMs show a markedly improved ambient stability when stored without encapsulation under ambient conditions with a relative humidity of 85% compared to devices containing doped Spiro-OMeTAD. This work thus provides a fundamental strategy for the future design of cost-effective and stable HTMs for PSCs and other optoelectronic devices.
|
|
