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- Ball, J, et al.
(författare)
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Practice nursing: what do we know?
- 2015
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Ingår i: The British journal of general practice : the journal of the Royal College of General Practitioners. - 1478-5242. ; 65:630, s. 10-11
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Donetto, S., et al.
(författare)
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Nursing work and sensory experiences of hospital design : A before and after qualitative study following a move to all-single room inpatient accommodation
- 2017
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Ingår i: Health and Place. - : Elsevier. - 1353-8292 .- 1873-2054. ; 46, s. 121-129
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Tidskriftsartikel (refereegranskat)abstract
- The embodied experience of nursing practice is rarely studied. Drawing on data from an internationally relevant larger study conducted in 2013–14, here we explore the sensory dimension of the embodied experiences of nursing staff working on two acute NHS hospital wards before and after a move to all-single room inpatient accommodation. We undertook a secondary analysis of 25 interviews with nursing staff (12 before and 13 after the move with half [13/25] using photographs taken by participants) from a mixed-method before-and-after study. This analysis focused on the sensory dimensions of nursing staff's experiences of their working practices and the effect of the built environment upon these. Drawing on Pallasmaa's theoretocal insights, we report how the all-single room ward design prioritises ‘focused vision’ and hinders peripheral perception, whilst the open ward environment is rich in contextual and preconscious information. We suggest all-single room accommodation may offer staff an impoverished experience of caring for patients and of working with each other.
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- Robert, Glenn, et al.
(författare)
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Exploring the adoption of Schwartz Center Rounds as an organisational innovation to improve staff well-being in England, 2009-2015
- 2017
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Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Schwartz Center Rounds ('Rounds') are a multidisciplinary forum in which healthcare staff within an organisation discuss the psychological, emotional and social challenges associated with their work in a confidential and safe environment. Implemented in over 375 North American organisations, since 2009, they have been increasingly adopted in England. This study aimed to establish how many and what types of organisations have adopted Rounds in England, and to explore why they did so.Setting: Public healthcare organisations in England.Participants: Secondary data analysis was used to map and profile all 116 public healthcare organisations that had adopted Rounds in England by July 2015. Semistructured telephone interviews were conducted with 45 Round coordinators within adopting organisations.Results: The rate of adoption increased after a major national report in 2013. Rounds were typically adopted in order to improve staff well-being. Adopting organisations scored better on staff engagement than non-adopters; among adopting organisations, those performing better on patient experience were more likely to adopt earlier. Most adoption decision-making processes were straightforward. A confluence of factors-a generally favourable set of innovation attributes (including low cost), advocacy from opinion leaders in different professional networks, active dissemination by change agents and a felt need to be seen to be addressing staff well-being-initially led to Rounds being seen as 'an idea whose time had come'. More recent adoption patterns have been shaped by the timing of charitable and other agency funding in specific geographical areas and sectors, as well as several forms of 'mimetic pressure'.Conclusions: The innate attributes of Rounds, favourable circumstances and the cumulative impact of a sequence of distinct informal and formal social processes have shaped the pattern of their adoption in England.
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- Mpakali, Anastasia, et al.
(författare)
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Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor
- 2020
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Ingår i: ACS Medicinal Chemistry Letters. - : AMER CHEMICAL SOC. - 1948-5875. ; 11:7, s. 1429-1434
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Tidskriftsartikel (refereegranskat)abstract
- Insulin-regulated aminopeptidase (IRAP) is a transmembrane zinc metallopeptidase with many important biological functions and an emerging pharmacological target. Although previous structural studies have given insight on how IRAP recognizes linear peptides, how it recognizes its physiological cyclic ligands remains elusive. Here, we report the first crystal structure of IRAP with the macrocyclic peptide inhibitor HA08 that combines structural elements from angiotensin IV and the physiological substrates oxytocin and vasopressin. The compound is found in the catalytic site in a near canonical substrate-like configuration and inhibits by a competitive mechanism. Comparison with previously solved structures of IRAP along with smallangle X-ray scattering experiments suggests that IRAP is in an open conformation in solution but undergoes a closing conformational change upon inhibitor binding. Stabilization of the closed conformation in combination with catalytic water exclusion by the tightly juxtaposed GAMEN loop is proposed as a mechanism of inhibition.
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- Rabi, Maben, 1977, et al.
(författare)
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Adaptive sampling for linear state estimation
- 2012
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Ingår i: SIAM Journal on Control and Optimization. - : Society for Industrial & Applied Mathematics (SIAM). - 1095-7138 .- 0363-0129. ; 50:2, s. 672-702
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Tidskriftsartikel (refereegranskat)abstract
- When a sensor has continuous measurements but sends occasional messages over a data network to a supervisor which estimates the state, the available packet rate fixes the achievable quality of state estimation. When such rate limits turn stringent, the sensor’s messaging policy should be designed anew. What are the good causal messaging policies ? What should message packets contain ? What is the lowest possible distortion in a causal estimate at the supervisor ? Is Delta sampling better than periodic sampling ? We answer these questions for a Markov state process under an idealized model of the network and the assumption of perfect state measurements at the sensor. If the state is a scalar, or a vector of low dimension, then we can ignore sample quantization. If in addition, we can ignore jitter in the transmission delays over the network, then our search for efficient messaging policies simplifies. Firstly, each message packet should contain the value of the state at that time. Thus a bound on the number of data packets becomes a bound on the number of state samples. Secondly, the remaining choice in messaging is entirely about the times when samples are taken. For a scalar, linear diffusion process, we study the problem of choosing the causal sampling times that will give the lowest aggregate squared error distortion. We stick to finite-horizons and impose a hard upper bound N on the number of allowed samples. We cast the design as a problem of choosing an optimal sequence of stopping times. We reduce this to a nested sequence of problems, each asking for a single optimal stopping time. Under an unproven but natural assumption about the least-square estimate at the supervisor, each of these single stopping problems are of standard form. The optimal stopping times are random times when the estimation error exceeds designed envelopes. For the case where the state is a Brownian motion, we give analytically: the shape of the optimal sampling envelopes, the shape of the envelopes under optimal Delta sampling, and their performances. Surprisingly, we find that Delta sampling performs badly. Hence, when the rate constraint is a hard limit on the number of samples over a finite horizon, we should should not use Delta sampling.
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- Rasmussen, Bodil, et al.
(författare)
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Letter to the editor
- 2023
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Ingår i: Journal of Advanced Nursing. - 0309-2402 .- 1365-2648. ; 79:7, s. 2774-2775
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Tidskriftsartikel (refereegranskat)
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