| 1. |
- Matejicek, Jiri, et al.
(författare)
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Interaction of candidate plasma facing materials with tokamak plasma in COMPASS
- 2017
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Ingår i: Journal of Nuclear Materials. - : ELSEVIER SCIENCE BV. - 0022-3115 .- 1873-4820. ; 493, s. 102-119
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Tidskriftsartikel (refereegranskat)abstract
- The interaction of tokamak plasma with several materials considered for the plasma facing components of future fusion devices was studied in a small-size COMPASS tokamak. These included mainly tungsten as the prime candidate and chromium steel as an alternative whose suitability was to be assessed. For the experiments, thin coatings of tungsten, P92 steel and nickel on graphite substrates were prepared by arc-discharge sputtering. The samples were exposed to hydrogen and deuterium plasma discharges in the COMPASS tokamak in two modes: a) short exposure (several discharges) on a manipulator in the proximity of the separatrix, close to the central column, and b) long exposure (several months) at the central column, aligned with the other graphite tiles. During the discharges, standard plasma diagnostics were used and a local emission of spectral lines in the visible near ultraviolet regions, corresponding to the material erosion, was monitored. Before and after the plasma exposures, the sample surfaces were observed using scanning electron microscopy, the coatings thickness was measured using Rutherford backscattering spectroscopy, and the concentration profiles of hydrogen and deuterium were measured by elastic recoil detection analysis. The uniformity of the coatings and their thickness was verified before the exposure. After the exposure, no reduction of the thickness was observed, indicating the absence of 'global' erosion. Erosion was observed only in isolated spots, and attributed to unipolar arcing. Slightly larger erosion was found on the steel coatings compared to the tungsten ones. Incorporation of deuterium in a thin surface layer was observed, in dependence on the exposure mode. Additionally, boron enrichment of the long-exposure samples was observed, as a result of the tokamak chamber boronization.
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| 2. |
- Niroomand, Anna, et al.
(författare)
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Corticotropin releasing hormone as an identifier of bronchiolitis obliterans syndrome
- 2022
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 12, s. 1-11
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Tidskriftsartikel (refereegranskat)abstract
- Lung transplantion (LTx) recipients have low long-term survival and a high incidence of bronchiolitis obliterans syndrome (BOS), an inflammation of the small airways in chronic rejection of a lung allograft. There is great clinical need for a minimally invasive biomarker of BOS. Here, 644 different proteins were analyzed to detect biomarkers that distinguish BOS grade 0 from grades 1-3. The plasma of 46 double lung transplant patients was analyzed for proteins using a high-component, multiplex immunoassay that enables analysis of protein biomarkers. Proximity Extension Assay (PEA) consists of antibody probe pairs which bind to targets. The resulting polymerase chain reaction (PCR) reporter sequence can be quantified by real-time PCR. Samples were collected at baseline and 1-year post transplantation. Enzyme-linked immunosorbent assay (ELISA) was used to validate the findings of the PEA analysis across both time points and microarray datasets from other lung transplantation centers demonstrated the same findings. Significant decreases in the plasma protein levels of CRH, FERC2, IL-20RA, TNFB, and IGSF3 and an increase in MMP-9 and CTSL1 were seen in patients who developed BOS compared to those who did not. In this study, CRH is presented as a novel potential biomarker in the progression of disease because of its decreased levels in patients across all BOS grades. Additionally, biomarkers involving the remodeling of the extracellular matrix (ECM), such as MMP-9 and CTSL1, were increased in BOS patients.
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| 3. |
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Nuclear physics for cultural heritage : A topical review by the Nuclear Physics Division of the European Physical Society
- 2016. - 1
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Samlingsverk (redaktörskap) (populärvet., debatt m.m.)abstract
- Nuclear physics applications in medicine and energy are well known and widely reported. Less well known are the many important nuclear and related techniques used for the study, characterization, assessment and preservation of cultural heritage. There has been enormous progress in this field in recent years and the current review aims to provide the public with a popular and accessible account of this work.The Nuclear Physics Division of the EPS represents scientists from all branches of nuclear physics across Europe. One of its aims is the dissemination of knowledge about nuclear physics and its applications. This review is led by Division board member Anna Macková, Head of the Tandetron Laboratory at the Nuclear Physics Institute of the Czech Academy of Sciences, and the review committee includes four other members of the nuclear physics board interested in this area: Faiçal Azaiez, Johan Nyberg, Eli Piasetzky and Douglas MacGregor. To create a truly authoritative account, the Scientific Editors have invited contributions from leading experts across Europe, and this publication is the combined result of their work.The review is extensively illustrated with important discoveries and examples from archaeology, pre-history, history, geography, culture, religion and curation, which underline the breadth and importance of this field. The large number of groups and laboratories working in the study and preservation of cultural heritage across Europe indicate the enormous effort and importance attached by society to this activity.
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