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Sökning: WFRF:(Magerl M)

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  • Maurer, M, et al. (författare)
  • New topics in bradykinin research
  • 2011
  • Ingår i: Allergy. - : Wiley. - 1398-9995 .- 0105-4538. ; 66:11, s. 1397-1406
  • Tidskriftsartikel (refereegranskat)abstract
    • Bradykinin has been implicated to contribute to allergic inflammation and the pathogenesis of allergic conditions. It binds to endothelial B(1) and B(2) receptors and exerts potent pharmacological and physiological effects, notably, decreased blood pressure, increased vascular permeability and the promotion of classical symptoms of inflammation such as vasodilation, hyperthermia, oedema and pain. Towards potential clinical benefit, bradykinin has also been shown to exert potent antithrombogenic, antiproliferative and antifibrogenic effects. The development of pharmacologically active substances, such as bradykinin receptor blockers, opens up new therapeutic options that require further research into bradykinin. This review presents current understanding surrounding the role of bradykinin in nonallergic angioedema and other conditions seen by allergists and emergency physicians, and its potential role as a therapeutic target.
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  • Esbjörnsson Elgh, Björn Neo, 1980, et al. (författare)
  • Controlling morphology, mesoporosity, crystallinity, and photocatalytic activity of ordered mesoporous TiO2 films prepared at low temperature
  • 2014
  • Ingår i: APL Materials. - : AIP Publishing. - 2166-532X. ; 2:11, s. Art. no. 113313-
  • Tidskriftsartikel (refereegranskat)abstract
    • Partly ordered mesoporous titania films with anatase crystallites incorporated into the pore walls were prepared at low temperature by spin-coating a microemulsion-based reaction solution. The effect of relative humidity employed during aging of the prepared films was studied using SEM, TEM, and grazing incidence small angle X-ray scattering to evaluate the mesoscopic order, porosity, and crystallinity of the films. The study shows unambiguously that crystal growth occurs mainly during storage of the films and proceeds at room temperature largely depending on relative humidity. Porosity, pore size, mesoscopic order, crystallinity, and photocatalytic activity of the films increased with relative humidity up to an optimum around 75%.
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