| 1. |
- Bogers, M., et al.
(författare)
-
The open innovation research landscape : established perspectives and emerging themes across different levels of analysis
- 2017
-
Ingår i: Industry and Innovation. - : Routledge. - 1366-2716 .- 1469-8390. ; 24:1, s. 8-40
-
Tidskriftsartikel (refereegranskat)abstract
- This paper provides an overview of the main perspectives and themes emerging in research on open innovation (OI). The paper is the result of a collaborative process among several OI scholars–having a common basis in the recurrent Professional Development Workshop on ‘Researching Open Innovation’ at the Annual Meeting of the Academy of Management. In this paper, we present opportunities for future research on OI, organised at different levels of analysis. We discuss some of the contingencies at these different levels, and argue that future research needs to study OI–originally an organisational-level phenomenon–across multiple levels of analysis. While our integrative framework allows comparing, contrasting and integrating various perspectives at different levels of analysis, further theorising will be needed to advance OI research. On this basis, we propose some new research categories as well as questions for future research–particularly those that span across research domains that have so far developed in isolation.
|
|
| 2. |
- Colombo, Massimo G., et al.
(författare)
-
Introduction : Small Business and Networked Innovation: Organizational and Managerial Challenges
- 2012
-
Ingår i: Journal of small business management (Print). - 0047-2778 .- 1540-627X. ; 50:2, s. 181-190
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of this article is to provide an introduction to the special issue. We briefly consider the organizational and managerial challenges that small and medium-sized enterprises encounter in networked innovation, thereby building a background to the articles included in the special issue. We then present the main findings of these articles and highlight their novel contributions.
|
|
| 3. |
|
|
| 4. |
- Fernandes, Oswaldo J. C. B., et al.
(författare)
-
Prognostic factors for the survival of surgically treated patients for non-small cell lung cancer
- 2003
-
Ingår i: Acta Oncologica. - Oslo, Norway : Taylor & Francis. - 0284-186X .- 1651-226X. ; 42:4, s. 338-341
-
Tidskriftsartikel (refereegranskat)abstract
- The survival and outcome rates of 284 patients who underwent surgical treatment for non-small cell lung cancer were assessed retrospectively. Resectability rate was 94.1%, hospital mortality 3.9% (n = 11) and the mortality rates in patients who underwent pneumonectomy or lobectomy were 8.9% and 0.6%, respectively. The overall 5-year survival was 43.6%. Female gender, earlier stages of disease and a complete resection were strongly predictive for a long-term survival. Women in stage IA disease had a 5-year survival rate of 92.7%. The 5-year survival rate for patients in stages IIIA and N2 disease who underwent a complete resection was 21.9%, and 9% for those who did not undergo a complete resection. It is concluded that the best surgical results were observed in women who were operated on at an early stage of disease. A complete resection also contributed to a better outcome, even for patients in stage IIIA and N2 disease.
|
|
| 5. |
- Magnusson, Helene, et al.
(författare)
-
The effect of degree of branching on the rheological and thermal properties of hyperbranched aliphatic polyethers
- 2002
-
Ingår i: Polymer. - 0032-3861 .- 1873-2291. ; 43:2, s. 301-306
-
Tidskriftsartikel (refereegranskat)abstract
- A series of hyperbranched aliphatic polyethers with different degree of branching (DB) and molecular weights have been studied with respect to their rheological and thermal properties. The DB was shown to affect the ability of the polymers to crystallize and thereby also the rheological properties of the polymers. A low DB resulted in semi-crystalline polymers with melting points between 100 and 130 degreesC. The polymers with a higher DB were essentially amorphous and behaved as non-entangled Newtonian liquids in the molten state.
|
|
| 6. |
- Magnusson, Kristina, et al.
(författare)
-
Specific Uptake of an Amyloid-beta Protofibril-Binding Antibody-Tracer in A beta PP Transgenic Mouse Brain
- 2013
-
Ingår i: Journal of Alzheimer's Disease. - 1387-2877 .- 1875-8908. ; 37:1, s. 29-40
-
Tidskriftsartikel (refereegranskat)abstract
- Evidence suggests that amyloid-beta (A beta) protofibrils/oligomers are pathogenic agents in Alzheimer's disease (AD). Unfortunately, techniques enabling quantitative estimates of these species in patients or patient samples are still rather limited. Here we describe the in vitro and ex vivo characteristics of a new antibody-based radioactive ligand, [I-125]mAb158, which binds to A beta protofibrils with high affinity. [I-125]mAb158 was specifically taken up in brain of transgenic mice expressing amyloid-beta protein precursor (A beta PP) as shown ex vivo. This was in contrast to [I-125]mAb-Ly128 which does not bind to A beta. The uptake of intraperitoneally-administered [I-125]mAb158 into the brain was age- and time-dependent, and saturable in A beta PP transgenic mice with modest A beta deposition. Brain uptake was also found in young A beta PP transgenic mice that were devoid of A beta deposits, suggesting that [I-125]mAb158 targets soluble A beta protofibrils. The radioligand was diffusely located in the parenchyma, sometimes around senile plaques and only occasionally colocalized with cerebral amyloid angiopathy. A refined iodine-124-labeled version of mAb158 with much improved blood-brain barrier passage and a shorter plasma half-life might be useful for PET imaging of A beta protofibrils.
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
- Vuorinen, Katariina E.M., et al.
(författare)
-
Growth rings show limited evidence for ungulates' potential to suppress shrubs across the Arctic
- 2022
-
Ingår i: Environmental Research Letters. - : IOP Publishing. - 1748-9318 .- 1748-9326. ; 17:3
-
Tidskriftsartikel (refereegranskat)abstract
- Global warming has pronounced effects on tundra vegetation, and rising mean temperatures increase plant growth potential across the Arctic biome. Herbivores may counteract the warming impacts by reducing plant growth, but the strength of this effect may depend on prevailing regional climatic conditions. To study how ungulates interact with temperature to influence growth of tundra shrubs across the Arctic tundra biome, we assembled dendroecological data from 20 sites, comprising 1153 individual shrubs and 223 63 annual growth rings. Evidence for ungulates suppressing shrub radial growth was only observed at intermediate summer temperatures (6.5 °C-9 °C), and even at these temperatures the effect was not strong. Multiple factors, including forage preferences and landscape use by the ungulates, and favourable climatic conditions enabling effective compensatory growth of shrubs, may weaken the effects of ungulates on shrubs, possibly explaining the weakness of observed ungulate effects. Earlier local studies have shown that ungulates may counteract the impacts of warming on tundra shrub growth, but we demonstrate that ungulates' potential to suppress shrub radial growth is not always evident, and may be limited to certain climatic conditions.
|
|
