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- Lindgren, Arne G., et al.
(författare)
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International stroke genetics consortium recommendations for studies of genetics of stroke outcome and recovery
- 2022
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Ingår i: International Journal of Stroke. - : SAGE Publications. - 1747-4930 .- 1747-4949. ; 17:3, s. 260-268
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Tidskriftsartikel (refereegranskat)abstract
- Numerous biological mechanisms contribute to outcome after stroke, including brain injury, inflammation, and repair mechanisms. Clinical genetic studies have the potential to discover biological mechanisms affecting stroke recovery in humans and identify intervention targets. Large sample sizes are needed to detect commonly occurring genetic variations related to stroke brain injury and recovery. However, this usually requires combining data from multiple studies where consistent terminology, methodology, and data collection timelines are essential. Our group of expert stroke and rehabilitation clinicians and researchers with knowledge in genetics of stroke recovery here present recommendations for harmonizing phenotype data with focus on measures suitable for multicenter genetic studies of ischemic stroke brain injury and recovery. Our recommendations have been endorsed by the International Stroke Genetics Consortium.
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- Furtak, Lukas J., et al.
(författare)
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A variable active galactic nucleus at z = 2.06 triply-imaged by the galaxy cluster MACS J0035.4−2015
- 2023
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Ingår i: Monthly Notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 522:4, s. 5142-5151
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Tidskriftsartikel (refereegranskat)abstract
- We report the discovery of a triply imaged active galactic nucleus (AGN), lensed by the galaxy cluster MACS J0035.4−2015 (z d = 0.352). The object is detected in Hubble Space Telescope imaging taken for the RELICS program. It appears to have a quasi-stellar nucleus consistent with a point-source, with a de-magnified radius of re ≲ 100 pc. The object is spectroscopically confirmed to be an AGN at z spec = 2.063 ± 0.005 showing broad rest-frame UV emission lines, and detected in both X-ray observations with Chandra and in ALCS ALMA band 6 (1.2 mm) imaging. It has a relatively faint rest-frame UV luminosity for a quasar-like object, MUV, 1450 = −19.7 ± 0.2. The object adds to just a few quasars or other X-ray sources known to be multiply lensed by a galaxy cluster. Some diffuse emission from the host galaxy is faintly seen around the nucleus, and there is a faint object nearby sharing the same multiple-imaging symmetry and geometric redshift, possibly an interacting galaxy or a star-forming knot in the host. We present an accompanying lens model, calculate the magnifications and time delays, and infer the physical properties of the source. We find the rest-frame UV continuum and emission lines to be dominated by the AGN, and the optical emission to be dominated by the host galaxy of modest stellar mass M✶ ≃ 109.2 M⊙. We also observe some variation in the AGN emission with time, which may suggest that the AGN used to be more active. This object adds a low-redshift counterpart to several relatively faint AGN recently uncovered at high redshifts with HST and JWST.
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- Jha, Abhishek Kumar Rajesh, et al.
(författare)
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Comparison of Methods for Calculating Indirect Upstream Carbon Emissions from Information and Communication Technology Manufacturing
- 2023
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Ingår i: WSEAS Transactions on Environment and Development. - 1790-5079 .- 2224-3496. ; 19, s. 1045-1057
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Tidskriftsartikel (refereegranskat)abstract
- The use of Information Communication technology (ICT) is rapidly increasing in an age ofdigitalization. Measurement of carbon dioxide equivalent (CO2e) emissions from ICT is crucial for reducingthem. Most ICT organizations focus on Scope 1 and 2 emissions as they have greater control over them, commonly ignoring Scope 3 emissions. Scope 3 Category 1 (S3C1) emissions occur throughout the rawmaterial acquisition and manufacturing stages of an ICT product's life cycle accounting for a large portion ofthe sector's overall CO2e emissions and energy consumption. By not reporting Scope 3 emissions, companieslose the ability to reduce their overall CO2e corporate emissions. Although Category 1 and 11 under Scope 3account for 85% of ICT's worldwide CO2e emissions, the methodologies for calculating S3C1 emissions in ICTare understudied. This study focuses on these emissions in the framework of Sustainable Development Goals 9,12, and 13. Product life cycle assessment (PLCA) and Spend-based methods have been used to analyze S3C1emissions in the ICT sector with two case examples of laptop computers and smartphones. The ExcelManagement Life Cycle Assessment (EMLCA) tool has been used for the S3C1 emissions estimation. PLCAand Spend-based methods are compared on their ability to calculate CO2e emissions. It is concluded that theSpend-based is faster than PLCA for predicting ICT emissions with modest uncertainty for smartphone andlaptop components. Furthermore, this work explores the advantages and downsides of both methods.
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