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| 2. |
- Andersson, Jesper, 1970-, et al.
(författare)
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Reflecting on self-adaptive software systems
- 2009
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Ingår i: Software Engineering for Adaptive and Self-Managing Systems, 2009. SEAMS '09. ICSE Workshop on. - 9781424437245 ; , s. 38-47
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Konferensbidrag (refereegranskat)
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| 3. |
- Bajbouj, Malek, et al.
(författare)
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Two-year outcome of vagus nerve stimulation in treatment-resistant depression
- 2010
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Ingår i: Journal of Clinical Psychopharmacology. - : Lippincott Williams & Wilkins. - 0271-0749 .- 1533-712X. ; 30:3, s. 273-281
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Tidskriftsartikel (refereegranskat)abstract
- One of the major goals of antidepressant treatment is a sustained response and remission of depressive symptoms. Some of the previous studies of vagus nerve stimulation (VNS) have suggested antidepressant effects. Our naturalistic study assessed the efficacy and the safety of VNS in 74 European patients with therapy-resistant major depressive disorder. Psychometric measures were obtained after 3, 12, and 24 months of VNS. Mixed-model repeated-measures analysis of variance revealed a significant reduction (P < or = 0.05) at all the 3 time points in the 28-item Hamilton Rating Scale for Depression (HRSD28) score, the primary outcome measure. After 2 years, 53.1% (26/49) of the patients fulfilled the response criteria (> or =50% reduction in the HRSD28 scores from baseline) and 38.9% (19/49) fulfilled the remission criteria (HRSD28 scores < or = 10). The proportion of patients who fulfilled the remission criteria remained constant as the duration of VNS treatment increased. Voice alteration, cough, and pain were the most frequently reported adverse effects. Two patients committed suicide during the study; no other deaths were reported. No statistically significant differences were seen in the number of concomitant antidepressant medications. The results of this 2-year open-label trial suggest a clinical response and a comparatively benign adverse effect profile among patients with treatment-resistant depression.
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| 4. |
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| 5. |
- de Lemos, Rogerio, et al.
(författare)
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Software Engineering for Self-Adaptive Systems : A Second Research Roadmap
- 2013
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Ingår i: Software Engineering for Self-Adaptive Systems II. - Berlin, Heidelberg : Springer. - 9783642358128 ; , s. 1-32
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The goal of this roadmap paper is to summarize the state-of-the-art and identify research challenges when developing, deploying and managing self-adaptive software systems. Instead of dealing with a wide range of topics associated with the field, we focus on four essential topics of self-adaptation: design space for self-adaptive solutions, software engineering processes for self-adaptive systems, from centralized to decentralized control, and practical run-time verification & validation for self-adaptive systems. For each topic, we present an overview, suggest future directions, and focus on selected challenges. This paper complements and extends a previous roadmap on software engineering for self-adaptive systems published in 2009 covering a different set of topics, and reflecting in part on the previous paper. This roadmap is one of the many results of the Dagstuhl Seminar 10431 on Software Engineering for Self-Adaptive Systems, which took place in October 2010.
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| 8. |
- Vromant, Pieter, et al.
(författare)
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On interacting control loops in self-adaptive systems
- 2011
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Ingår i: Proceedings of the 6th International Symposium on Software Engineering for Adaptive and Self-Managing Systems. - New York, NY, USA : ACM Press. - 9781450305754 ; , s. 202-207
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Bokkapitel (refereegranskat)
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| 9. |
- Weyns, Danny, et al.
(författare)
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Claims and Supporting Evidence for Self-Adaptive Systems : A Literature Study
- 2012
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Ingår i: ICSE Workshop on Software Engineering for Adaptive and Self-Managing Systems. - : IEEE. ; , s. 89-98
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Konferensbidrag (refereegranskat)abstract
- Despite the vast body of work on self-adaption, no systematic study has been performed on the claims associated with self-adaptation and the evidence that exists for these claims. As such an insight is crucial for researchers and engineers, we performed a literature study of the research results from SEAMS since 2006 and the associated Dagstuhl seminar in 2008. The study shows that the primary claims of self-adaptation are improved flexibility, reliability, and performance of the system. On the other hand, the tradeoffs implied by self-adaptation have not received much attention. Evidence is obtained from basic examples, or simply lacking. Few systematic empirical studies have been performed, and no industrial evidence is reported. From the study, we offer the following recommendations to move the field forward: to improve evaluation, researchers should make their assessment methods, tools and data publicly available; to deal with poor discussion of limitations, conferences/workshops should require an explicit section on limitations in engineering papers; to improve poor treatment of tradeoffs, this aspect should be an explicit subject of reviews; and finally, to enhance industrial validation, the best academy-industry efforts could be formally recognized by the community.
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| 10. |
- Weyns, Danny, et al.
(författare)
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FORMS : Unifying Reference Model for Formal Specification of Distributed Self-adaptive Systems
- 2012
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Ingår i: ACM Transactions on Autonomous and Adaptive Systems. - : ACM Press. - 1556-4665 .- 1556-4703. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- The challenges of pervasive and mobile computing environments, which are highly dynamic and unpredictable, have motivated the development of self-adaptive software systems. Although noteworthy successes have been achieved on many fronts, the construction of such systems remains significantly more challenging than traditional systems. We argue this is partially because researchers and practitioners have been struggling with the lack of a precise vocabulary for describing and reasoning about the key architectural characteristics of self-adaptive systems. Further exacerbating the situation is the fact that existing frameworks and guidelines do not provide an encompassing perspective of the different types of concerns in this setting. In this article, we present a comprehensive reference model, entitled FOrmal Reference Model for Self-adaptation (FORMS), that targets both issues. FORMS provides rigor in the manner such systems can be described and reasoned about. It consists of a small number of formally specified modeling elements that correspond to the key concerns in the design of self-adaptive software systems, and a set of relationships that guide their composition. We demonstrate FORMS's ability to precisely describe and reason about the architectural characteristics of distributed self-adaptive software systems through its application to several existing systems. FORMS's expressive power gives it a potential for documenting reusable architectural solutions (e.g., architectural patterns) to commonly encountered problems in this area.
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