| 1. |
- Baxevanidis, Pantelis, et al.
(författare)
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Group contribution-based LCA models to enable screening for environmentally benign novel chemicals in CAMD applications
- 2022
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Ingår i: AICHE Journal. - : Wiley. - 1547-5905 .- 0001-1541. ; 68:3
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Tidskriftsartikel (refereegranskat)abstract
- This study considers the development of suitable models for the estimation of life cycle assessment (LCA) indices of organic chemicals. Unlike state-of-the-art models, the tools developed here correlate LCA indices with the molecular composition according to the well-established group contribution (GC) approach. The LCA indices considered here are global warming potential, cumulative energy demand, and Eco-Indicator 99. The model development uses data from existing LCA databases, where each material is associated with its cradle-to-gate LCA metrics. A variety of regression and nonregression methodologies are recruited to achieve the optimum correlation. GC models can be used to screen for molecules with optimal and/or desirable properties, using appropriate molecular design synthesis algorithms. In this framework, the models developed here are linked to the design algorithm to enable the consideration of LCA features together with other properties, for the design of environmentally benign liquid–liquid extraction solvents.
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| 2. |
- Marcoulaki, Effie, et al.
(författare)
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Blueprint for a self-sustained European Centre for service provision in safe and sustainable innovation for nanotechnology
- 2021
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Ingår i: NanoImpact. - : Elsevier B.V.. - 2452-0748. ; 23
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Tidskriftsartikel (refereegranskat)abstract
- The coming years are expected to bring rapid changes in the nanotechnology regulatory landscape, with the establishment of a new framework for nano-risk governance, in silico approaches for characterisation and risk assessment of nanomaterials, and novel procedures for the early identification and management of nanomaterial risks. In this context, Safe(r)-by-Design (SbD) emerges as a powerful preventive approach to support the development of safe and sustainable (SSbD) nanotechnology-based products and processes throughout the life cycle. This paper summarises the work undertaken to develop a blueprint for the deployment and operation of a permanent European Centre of collaborating laboratories and research organisations supporting safe innovation in nanotechnologies. The proposed entity, referred to as “the Centre”, will establish a ‘one-stop shop’ for nanosafety-related services and a central contact point for addressing stakeholder questions about nanosafety. Its operation will rely on significant business, legal and market knowledge, as well as other tools developed and acquired through the EU-funded EC4SafeNano project and subsequent ongoing activities. The proposed blueprint adopts a demand-driven service update scheme to allow the necessary vigilance and flexibility to identify opportunities and adjust its activities and services in the rapidly evolving regulatory and nano risk governance landscape. The proposed Centre will play a major role as a conduit to transfer scientific knowledge between the research and commercial laboratories or consultants able to provide high quality nanosafety services, and the end-users of such services (e.g., industry, SMEs, consultancy firms, and regulatory authorities). The Centre will harmonise service provision, and bring novel risk assessment and management approaches, e.g. in silico methodologies, closer to practice, notably through SbD/SSbD, and decisively support safe and sustainable innovation of industrial production in the nanotechnology industry according to the European Chemicals Strategy for Sustainability.
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| 3. |
- Shandilya, Neeraj, et al.
(författare)
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Blueprint for the Development and Sustainability of National Nanosafety Centers
- 2020
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Ingår i: NanoEthics. - : Springer. - 1871-4757 .- 1871-4765. ; 14, s. 169-183
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Tidskriftsartikel (refereegranskat)abstract
- This work presents a blueprint or set of guidelines for the planning and development of sustainable national centers dealing with the safety of nanomaterials and nanotechnologies toward public health and environment. The blueprint was developed following a methodological approach of EU-wide online survey and workshop with several stakeholders. The purpose was to identify the key elements and challenges in the development and sustainability of a national nanosafety center. The responses were received from representatives of 16 national nanosafety centers across Europe and 44 people from 18 EU member states who represented the stakeholder groups of researchers, academics, industry, regulators, civil society, and consultants. By providing an overview of the organizational design of existing national nanosafety centers across EU and converging demands in the field of nanosafety, the blueprint principally benefits those EU member states who do not have a national nanosafety center, but intend to develop an entity to manage the human health, environmental, ethical, and social concerns/risks toward the growing nationwide activities on engineered nanomaterials, e.g., their production, use or disposal, at national level. © 2020, The Author(s).
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