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- Marcu, Loredana G., et al.
(författare)
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Radiotherapy and clinical radiobiology of head and neck cancer
- 2018
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Bok (refereegranskat)abstract
- Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer.
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- Marcu, Loredana G., et al.
(författare)
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The six Rs of head and neck cancer radiotherapy
- 2015
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Ingår i: Contemporary Issues in Head and Neck Cancer Management. - Rijeka : InTech. - 9789535121350 ; , s. 35-58
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Bokkapitel (refereegranskat)abstract
- While the management of head and neck cancer has evolved over the last few decades, there are still several challenges and unanswered questions that need solutions. This book is a small compilation of some topical aspects regarding head and neck cancer treatment, including the etiology of HPV-positive oropharyngeal cancers and risk factors in the young population, the challenge of surgical margin definition and the perennial problem of systemic treatment due to distant metastases. Radiobiological aspects are also covered through the Rs of radiotherapy, with a couple of chapters being dedicated to radioresistance and tumour microenvironment. Contemporary Issues in Head and Neck Cancer Management comes as an addition to the existing literature that aims to tackle this radiobiologically challenging tumour.
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