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- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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- Drake, TM, et al.
(författare)
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Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
- 2020
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Ingår i: BMJ global health. - : BMJ. - 2059-7908. ; 5:12
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Tidskriftsartikel (refereegranskat)abstract
- Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings.MethodsA multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI).ResultsOf 1159 children across 181 hospitals in 51 countries, 523 (45·1%) children were from high HDI, 397 (34·2%) from middle HDI and 239 (20·6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12·8% (51/397) in middle HDI and 24·7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI.ConclusionThe odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.
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| 5. |
- Guerster, M., et al.
(författare)
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Permanent crewed Mars base by 2030 - Outcomes of an interdisciplinary, multinational student workshop
- 2018
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Ingår i: Proceedings of the International Astronautical Congress, IAC 2018. - : International Astronautical Federation, IAF.
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Konferensbidrag (refereegranskat)abstract
- Indisputably, we live at the dawn of a novel space exploration era, with the space sector undergoing significant changes. The International Space Station (ISS) is nearing the end of its lifespan and a competitive space industry is emerging. It is characterised by an ongoing redistribution of responsibilities between government agencies and private enterprise, with all stakeholders setting ambitious goals for future missions. Recently, interest in the next crewed space exploration mission has grown continuously. Driven by these developments, the Space Station Design Workshop (SSDW) 2017 in Stuttgart, Germany, posed the challenge to conduct the preliminary analysis and develop a viable proposal for the establishment of a permanent crewed space station in the vicinity of Mars by the year 2030. Two multinational, interdisciplinary teams of twenty students each were given one week to develop their own solutions and present them to experts from industry and academia. The authors, Team Blue, have outlined a design for a Mars surface station, called HUMANS2MARS. This proposal requires the development of mission-specific modules, while the launchers to be used include the foreseen state-of-the-art at the late 2020s, such as the Space Launch System from NASA and Falcon Heavy from SpaceX. Designing such a mission from scratch in one week posed great challenges, either innate in the technical and programmatic difficulties of the mission, or resulting from the time constraints and group dynamics of the project. The main technical challenges can be grouped into two sets. The first includes those related to mass and payload limitations of the mission and launching costs. The second consists of those related to the human element of the mission. Due to the hostile Martian environment, like the extreme radiation levels during transit and unexplored psychological pressure on the crew, the complexities associated with humans introduce significant uncertainties. Potential solutions to the problems discovered have been proposed and are presented in this paper - within the framework of a multicultural and interdisciplinary workshop. The major risks of the proposed mission are identified and possible mitigation strategies and backup scenarios are discussed, thus providing a starting point for future research and detailed studies. The complexity of the mission and nature of the SSDW require addressing a great variety of challenges under severe time constraints. A crucial factor in the success of this effort has been the multidisciplinary and diverse academic background of the participants. This enabled the team to overcome these numerous obstacles in often unconventional ways.
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| 10. |
- Fragopoulou, A., et al.
(författare)
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Scientific panel on electromagnetic field health risks : Consensus points, recommendations, and rationales
- 2010
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Ingår i: Reviews on Environmental Health. - 0048-7554. ; 25:4, s. 307-317
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Tidskriftsartikel (refereegranskat)abstract
- In November, 2009, a scientific panel met in Seletun, Norway, for three days of intensive discussion on existing scientific evidence and public health implications of the unprecedented global exposures to artificial electromagnetic fields (EMF). EMF exposures (static to 300 GHz) result from the use of electric power and from wireless telecommunications technologies for voice and data transmission, energy, security, military and radar use in weather and transportation. The Scientific Panel recognizes that the body of evidence on EMF requires a new approach to protection of public health; the growth and development of the fetus, and of children; and argues for strong preventative actions. New, biologically-based public exposure standards are urgently needed to protect public health worldwide.
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