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| 2. |
- Zaborowski, AM, et al.
(författare)
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Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response
- 2022
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Ingår i: The British journal of surgery. - : Oxford University Press (OUP). - 1365-2168 .- 0007-1323. ; 109:3, s. 251-255
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Tidskriftsartikel (refereegranskat)abstract
- In this study of 400 patients with early-onset rectal cancer, 12.5 per cent demonstrated microsatellite instability (MSI). MSI was associated with a reduced likelihood of nodal positivity, an increased rate of pathological complete response, and improved disease-specific survival.
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| 3. |
- Arridge, Christopher S., et al.
(författare)
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Uranus Pathfinder : exploring the origins and evolution of Ice Giant planets
- 2012
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Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 33:2-3, s. 753-791
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Tidskriftsartikel (refereegranskat)abstract
- The "Ice Giants" Uranus and Neptune are a different class of planet compared to Jupiter and Saturn. Studying these objects is important for furthering our understanding of the formation and evolution of the planets, and unravelling the fundamental physical and chemical processes in the Solar System. The importance of filling these gaps in our knowledge of the Solar System is particularly acute when trying to apply our understanding to the numerous planetary systems that have been discovered around other stars. The Uranus Pathfinder (UP) mission thus represents the quintessential aspects of the objectives of the European planetary community as expressed in ESA's Cosmic Vision 2015-2025. UP was proposed to the European Space Agency's M3 call for medium-class missions in 2010 and proposed to be the first orbiter of an Ice Giant planet. As the most accessible Ice Giant within the M-class mission envelope Uranus was identified as the mission target. Although not selected for this call the UP mission concept provides a baseline framework for the exploration of Uranus with existing low-cost platforms and underlines the need to develop power sources suitable for the outer Solar System. The UP science case is based around exploring the origins, evolution, and processes at work in Ice Giant planetary systems. Three broad themes were identified: (1) Uranus as an Ice Giant, (2) An Ice Giant planetary system, and (3) An asymmetric magnetosphere. Due to the long interplanetary transfer from Earth to Uranus a significant cruise-phase science theme was also developed. The UP mission concept calls for the use of a Mars Express/Rosetta-type platform to launch on a Soyuz-Fregat in 2021 and entering into an eccentric polar orbit around Uranus in the 2036-2037 timeframe. The science payload has a strong heritage in Europe and beyond and requires no significant technology developments.
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| 4. |
- Parkin, David T, et al.
(författare)
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Species limits in Acrocephalus and Hippolais warblers from the Western Palearctic
- 2004
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Ingår i: British Birds. - 0007-0335. ; 97:6, s. 276-299
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- The taxonomic affiliations within the genera [Acrocephalus] and [Hippolais] have long been a matter for debate. Recent molecular and behavioural studies have provided a wealth of new data which can be used to analyse the evolutionary relationships of the Palearctic taxa in these genera. In this paper, we make a series of recommendations for changes in species limits, highlight some problem areas and discuss situations where more research is needed.
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| 5. |
- Raković, Marko, et al.
(författare)
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Geographic patterns of mtDNA and Z-linked sequence variation in the Common Chiffchaff and the ‘chiffchaff complex’
- 2019
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Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- The Common Chiffchaff Phylloscopus collybita is an abundant, polytypic Palearctic bird. Validity of some of its subspecies is controversial and birds from some parts of the species range remain unclassified taxonomically. The relationships among populations from different geographic areas have not been sufficiently explored with molecular data. In this study we analyzed the relationships among the four species in the ‘chiffchaff complex’ (Common Chiffchaff, Iberian Chiffchaff P. ibericus, Canary Islands Chiffchaff P. canariensis and Mountain Chiffchaff P. sindianus), and the patterns of intraspecific geographic variation in the mtDNA ND2 gene and intron 9 of the Z-linked aconitase gene (ACO1I9) across the Common Chiffchaff range, including a recently discovered population breeding on Mt. Hermon (Anti-Lebanon mountains). Our data supported the monophyly of the chiffchaff complex and its current systematics at the species level. Within the Common Chiffchaff, the Siberian race P. c. tristis was the most differentiated subspecies and may represent a separate or incipient species. Other Common Chiffchaff subspecies also were differentiated in their mtDNA, however, lineages of neighboring subspecies formed wide zones of introgression. The Mt. Hermon population was of mixed genetic origin but contained some birds with novel unique lineage that could not be assigned to known subspecies. All Common Chiffchaff lineages diverged at the end of the Ionian stage of Pleistocene. Lineage sorting of ACO1I9 alleles was not as complete as that of mtDNA. Chiffchaff species were mostly distinct at ACO1I9, except the Common and Canary Islands Chiffchaffs that shared multiple alleles. An AMOVA identified geographic structure in Common Chiffchaff ACO1I9 variation that was broadly consistent with that of mtDNA ND2 gene. The genetic and other data suggest the chiffchaff complex to be a group of evolutionarily young taxa that represent a paradigm of ‘species evolution in action’ from intergrading subspecies through to apparently complete biological speciation.
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| 7. |
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| 8. |
- Collinson, Martin, et al.
(författare)
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Species limits within the genus Melanitta, the scoters
- 2006
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Ingår i: British Birds. - 0007-0335. ; 99, s. 183-201
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- As part of its reassessment of the taxonomy of birds on the British List, the BOURC Taxonomic Sub-committee has assessed all six recognised taxa of scoters Melanitta against its previously published Species Guidelines (Helbig et al. 2002).We consider that, on the basis of evidence currently available, at least five species should be recognised: Common Scoter M. nigra, Black Scoter M. americana,Velvet Scoter M. fusca,White-winged Scoter M. deglandi and Surf Scoter M. perspicillata.The taxonomic status of the Asian subspecies of White-winged Scoter (stejnegeri) is uncertain, owing to insufficient information on several aspects of its morphology and behaviour. Provisionally, we suggest that it is best treated as conspecific with M. deglandi.
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| 9. |
- Helbig, Andreas J., et al.
(författare)
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Guidelines for assigning species rank
- 2002
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Ingår i: Ibis. - 0019-1019 .- 1474-919X. ; 144:3, s. 518-525
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Tidskriftsartikel (refereegranskat)abstract
- Developments in several fields of study (including bio-acoustics and the analysis of DNA) together with reappraisals of the nature of species have impacted significantly on avian taxonomy. The BOU’s Taxonomic Subcommittee has developed guidelines for the applicationof species limits to sympatric, parapatric, allopatric and hybridizing taxa. These are published here to assist researchers understand the rationale behind the committee’s taxonomic recommendations relating to the British List.
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