| 1. |
- Coelho, Denis A., 1971-, et al.
(författare)
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The benefits of occupational health and safety standards
- 2021. - 2. ed.
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Ingår i: Handbook of standards and guidelines in human factors and ergonomics. - Boca Raton : CRC Press. - 9781466594524 - 9780429169243 ; , s. 541-568
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- From Introduction: In this chapter, occupational health and safety is approached from the viewpoints of both Human Factors and Ergonomics and standardization, including management systems standards. The field of Occupational Health and Safety (OHS) is summarily characterized, and a historical perspective of its evolution is given, in relationship to Human Factors and Ergonomics (HFE). While several components of what makes the field of OHS up today pre-existed as specialized fields before, the foundation of the discipline of HFE (following World War II)—and some of the genesis of HFE, OHS, and HFE—have developed as two distinct, although somewhat overlapping, areas of ac-tivity. Links and commonalities can be found today between the two. Environmental conditions (such as noise, climate, or lighting) are an example of an area that is dealt with within the discipline of HFE and is also a central concern of OHS. While inadequate postures and movements at work and psychosocial factors impinge on OHS, HFE is equipped with knowledge and methods to perform the design of work and to deal with these work design factors. Regarding legislation, regulations, and standardization, OHS has gained a head start compared to HFE (the Occupational Safety and Health Act of 1970 in the U.S.A., the ILO R164 recommendation of 1981 at an in-ternational level, and the directive 89/391 on safety and health at work of 1989 in the EU), which supports the inclusion of this discussion on OHS standards within the realm of HFE standards, given the intersecting interests of the two disciplines. Regarding economic considerations, some HFE interventions have been the object of cost-benefit analyses reported in the literature. In what concerns OHS, the literature has focused on the cost of occupational accidents, injuries, illnesses, and fatalities. Estimates of costs and benefits of complying with (or adopting) OHS standards are also available in the form of literature dealing with the mandatory U.S. OSHA standards.
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| 2. |
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| 3. |
- Albers, Roland, et al.
(författare)
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Magnetospheric Venus Space Explorers (MVSE) mission : a proposal for understanding the dynamics of induced magnetospheres
- 2024
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Ingår i: Acta Astronautica. - : Elsevier. - 0094-5765 .- 1879-2030. ; 221, s. 194-205
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Tidskriftsartikel (refereegranskat)abstract
- Induced magnetospheres form around planetary bodies with atmospheres through the interaction of the solar wind with their ionosphere. Induced magnetospheres are highly dependent on the solar wind conditions and have only been studied with single spacecraft missions in the past. Without simultaneous measurements of solar wind variations and phenomena in the magnetosphere, establishing a link between both can only be done indirectly, using statistics over a large set of measurements. This gap in knowledge could be addressed by a multi-spacecraft plasma mission, optimized for studying global spatial and temporal variations in the magnetospheric system around Venus, which hosts the most prominent example of an induced magnetosphere in our solar system. The MVSE mission comprises four satellites, of which three are identical scientific spacecraft, carrying the same suite of instruments probing different regions of the induced magnetosphere and the solar wind simultaneously. The fourth spacecraft is the transfer vehicle which acts as a relay satellite for communications at Venus. In this way, changes in the solar wind conditions and extreme solar events can be observed, and their effects can be quantified as they propagate through the Venusian induced magnetosphere. Additionally, energy transfer in the Venusian induced magnetosphere can be investigated. The scientific payload includes instrumentation to measure the magnetic field, electric field, and ion–electron velocity distributions. This study presents the scientific motivation for the mission as well as requirements and the resulting mission design. Concretely, a mission timeline along with a complete spacecraft design, including mass, power, communication, propulsion and thermal budgets are given. This mission was initially conceived at the Alpbach Summer School 2022 and refined during a week-long study at ESA's Concurrent Design Facility in Redu, Belgium.
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| 4. |
- Bruneau, Anne, et al.
(författare)
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Advances in Legume Systematics 14. Classification of Caesalpinioideae. Part 2: Higher-level classification
- 2024
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Ingår i: PhytoKeys. - Sofia : Pensoft Publishers. - 1314-2011 .- 1314-2003. ; 240, s. 1-552
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Tidskriftsartikel (refereegranskat)abstract
- Caesalpinioideae is the second largest subfamily of legumes (Leguminosae) with ca. 4680 species and 163 genera. It is an ecologically and economically important group formed of mostly woody perennials that range from large canopy emergent trees to functionally herbaceous geoxyles, lianas and shrubs, and which has a global distribution, occurring on every continent except Antarctica. Following the recent re-circumscription of 15 Caesalpinioideae genera as presented in Advances in Legume Systematics 14, Part 1, and using as a basis a phylogenomic analysis of 997 nuclear gene sequences for 420 species and all but five of the genera currently recognised in the subfamily, we present a new higher-level classification for the subfamily. The new classification of Caesalpinioideae comprises eleven tribes, all of which are either new, reinstated or re-circumscribed at this rank: Caesalpinieae Rchb. (27 genera / ca. 223 species), Campsiandreae LPWG (2 / 5-22), Cassieae Bronn (7 / 695), Cera-tonieae Rchb. (4 / 6), Dimorphandreae Benth. (4 / 35), Erythrophleeae LPWG (2 /13), Gleditsieae Nakai (3 / 20), Mimoseae Bronn (100 / ca. 3510), Pterogyneae LPWG (1 / 1), Schizolobieae Nakai (8 / 42-43), Sclerolobieae Benth. & Hook. f. (5 / ca. 113). Although many of these lineages have been recognised and named in the past, either as tribes or informal generic groups, their circumscriptions have varied widely and changed over the past decades, such that all the tribes described here differ in generic membership from those previously recognised. Importantly, the approximately 3500 species and 100 genera of the former subfamily Mimosoideae are now placed in the reinstated, but newly circumscribed, tribe Mimoseae. Because of the large size and ecological importance of the tribe, we also provide a clade-based classification system for Mimoseae that includes 17 named lower-level clades. Fourteen of the 100 Mimoseae genera remain unplaced in these lower-level clades: eight are resolved in two grades and six are phylogenetically isolated monogeneric lineages. In addition to the new classification, we provide a key to genera, morphological descriptions and notes for all 163 genera, all tribes, and all named clades. The diversity of growth forms, foliage, flowers and fruits are illustrated for all genera, and for each genus we also provide a distribution map, based on quality-controlled herbarium specimen localities. A glossary for specialised terms used in legume morphology is provided. This new phylogenetically based classification of Caesalpinioideae provides a solid system for communication and a framework for downstream analyses of biogeography, trait evolution and diversification, as well as for taxonomic revision of still understudied genera.
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| 5. |
- He, Minghui, et al.
(författare)
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Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation
- 2022
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Ingår i: Journal of Allergy and Clinical Immunology. - : Elsevier BV. - 0091-6749 .- 1097-6825. ; 149:3, s. 1069-1084
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: B-cell affinity maturation in germinal center relies on regulated actin dynamics for cell migration and cell-to-cell communication. Activating mutations in the cytoskeletal regulator Wiskott-Aldrich syndrome protein (WASp) cause X-linked neutropenia (XLN) with reduced serum level of IgA.OBJECTIVE: We investigated the role of B cells in XLN pathogenesis.METHODS: We examined B cells from 6 XLN patients, 2 of whom had novel R268W and S271F mutations in WASp. By using immunized XLN mouse models that carry the corresponding patient mutations, WASp L272P or WASp I296T, we examined the B-cell response.RESULTS: XLN patients had normal naive B cells and plasmablasts, but reduced IgA+ B cells and memory B cells, and poor B-cell proliferation. On immunization, XLN mice had a 2-fold reduction in germinal center B cells in spleen, but with increased generation of plasmablasts and plasma cells. In vitro, XLN B cells showed reduced immunoglobulin class switching and aberrant cell division as well as increased production of immunoglobulin-switched plasma cells.CONCLUSIONS: Overactive WASp predisposes B cells for premature differentiation into plasma cells at the expense of cell proliferation and immunoglobulin class switching.
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| 7. |
- Martinetti, Alberto, et al.
(författare)
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Maintenance 4.0 : Where Are We? A Systematic Literature Review
- 2020
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Ingår i: Applications and Challenges of Maintenance and Safety Engineering in Industry 4.0. - : IGI Global. ; , s. 1-30
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Bokkapitel (refereegranskat)abstract
- Aiming to remain competitive, companies from diverse industries are paying more attention to Industry 4.0 concept and its benefits. Maintenance is seen as a specific area of action to successfully sustain a competitive leverage, and its fusion with Industry 4.0 is perceived to revolutionize the whole maintenance concept. Maintenance 4.0 emerges as a subset of Industry 4.0 in the form of self-learning and smart system that predicts failures, makes diagnoses, and establishes maintenance actions. This chapter presents a systematic literature review (SLR) on Maintenance 4.0, with the aim of outlining the current achievements as well as limitations of maintenance meeting Industry 4.0 demands. The analysis included 90 papers selected as being the most suitable to reach the proposed goal. A state of the art on Maintenance 4.0 is performed, followed by an analysis ambitioning the delineation of what future holds on this topic.
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| 8. |
- Rosalino, Luís M., et al.
(författare)
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Three decades of research on Iberian wild Carnivora : trends, highlights, and future directions
- 2023
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Ingår i: Mammal Review. - : John Wiley & Sons. - 0305-1838 .- 1365-2907. ; 53:4, s. 254-270
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Forskningsöversikt (refereegranskat)abstract
- Mammalian carnivores (Carnivora) are crucial components of landscapes, because of both their top-down effects on lower trophic level species and their sensitivity to bottom-up processes, such as limited food resources (e.g. due to climate instability). To understand their functional role in Iberian ecosystems more clearly, and to define effective plans for their management and conservation, it is crucial to sum up the available regional knowledge that can inform decision-making processes.We review bio-ecological research on wild Iberian carnivores over 30 years (1990–2020) and identify key knowledge gaps and priority avenues for future research. Based on a systematic review of the scientific literature, we aimed to: 1) summarise current knowledge; 2) assess species and ecoregion representativeness; 3) identify key research topics addressed and those lacking investment and 4) suggest key future research priorities.We examined 920 peer-reviewed articles involving wild Iberian mammalian carnivores, focusing on different bio-ecological issues. We found considerable heterogeneity in the topics and species investigated, as well as in the study areas (ecoregions) explored, with a mismatch between the research priorities identified by researchers and the knowledge gaps.We suggest that future research should prioritise: 1) rear-edge populations that are at the southwestern limits of the species' Eurasian range, thus being particularly sensitive to the increasing fragmentation and aridity of Iberian ecosystems, and that were less studied (e.g. brown bear Ursus arctos, stoat Mustela erminea, European mink Mustela lutreola and pine marten Martes martes); 2) less-studied topics, such as morphometry and body condition, ecophysiology, and reproductive biology, all of which provide essential information for species' management and conservation and 3) specific ecoregions for which studies on species' adaptations to environmental and anthropic contexts are lacking (e.g. northern ecoregions of Iberia, Iberian conifer forests and Northwest Iberian montane forests). Our review provides the necessary background to support future research on carnivore populations in Iberia.
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| 9. |
- Saadallah, Amal, et al.
(författare)
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BRIGHT - Drift-Aware Demand Predictions for Taxi Networks
- 2020
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Ingår i: IEEE Transactions on Knowledge and Data Engineering. - : IEEE. - 1041-4347 .- 1558-2191. ; 32:2, s. 234-245
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Tidskriftsartikel (refereegranskat)abstract
- Massive data broadcast by GPS-equipped vehicles provide unprecedented opportunities. One of the main tasks in order to optimize our transportation networks is to build data-driven real-time decision support systems. However, the dynamic environments where the networks operate disallow the traditional assumptions required to put in practice many off-the-shelf supervised learning algorithms, such as finite training sets or stationary distributions. In this paper, we propose BRIGHT: a drift-aware supervised learning framework to predict demand quantities. BRIGHT aims to provide accurate predictions for short-term horizons through a creative ensemble of time series analysis methods that handles distinct types of concept drift. By selecting neighborhoods dynamically, BRIGHT reduces the likelihood of overfitting. By ensuring diversity among the base learners, BRIGHT ensures a high reduction of variance while keeping bias stable. Experiments were conducted using three large-scale heterogeneous real-world transportation networks in Porto (Portugal), Shanghai (China) and Stockholm (Sweden), as well as controlled experiments using synthetic data where multiple distinct drifts were artificially induced. The obtained results illustrate the advantages of BRIGHT in relation to state-of-the-art methods for this task.
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| 10. |
- Saadallah, Amal, et al.
(författare)
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BRIGHT - Drift-Aware Demand Predictions for Taxi Networks
- 2019
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Ingår i: 2019 IEEE 35TH INTERNATIONAL CONFERENCE ON DATA ENGINEERING (ICDE 2019). - : IEEE. - 9781538674741 ; , s. 2145-2146
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Konferensbidrag (refereegranskat)abstract
- The dynamic behavior of urban mobility patterns makes matching taxi supply with demand as one of the biggest challenges in this industry. Recently, the increasing availability of massive broadcast GPS data has encouraged the exploration of this issue under different perspectives. One possible solution is to build a data-driven real-time taxi-dispatching recommender system. However, existing systems are based on strong assumptions such as stationary demand distributions and finite training sets, which make them inadequate for modeling the dynamic nature of the network. In this paper, we propose BRIGHT: a drift-aware supervised learning framework which aims to provide accurate predictions for short-term horizon taxi demand quantities through a creative ensemble of time series analysis methods that handle distinct types of concept drift. A large experimental set-up which includes three real-world transportation networks and a synthetic test-bed with artificially inserted concept drifts, was employed to illustrate the advantages of BRIGHT when compared to S.o.A methods for this problem.
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