| 1. |
- Avetisyan, A., et al.
(författare)
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Preface
- 2019
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Ingår i: APSSE 2019 Actual Problems of System and Software Engineering. - : CEUR-WS. ; , s. 1-2
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Konferensbidrag (refereegranskat)
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| 2. |
- Bäck, S A, et al.
(författare)
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Verification of single beam treatment planning using a ferrous dosimeter gel and MRI (FeMRI)
- 1998
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Ingår i: Acta Oncologica. - 0284-186X. ; 37:6, s. 6-561
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Tidskriftsartikel (refereegranskat)abstract
- A method for analysing and comparing treatment planning system (TPS) data and ferrous dosimeter gel measurements evaluated with MRI (FeMRI) was developed, including image processing to final absorbed dose images. Measurements were analysed according to this method and FeMRI data were thereby compared with the TPS-calculated dose distribution. For photons, differences between FeMRI- and TPS dose data were mainly within +/- 2%. Minor shortcomings found in both the FeMRI system and the TPS are explained and discussed. For electron beams, there was an overall good agreement. It was found that the TPS underestimates the lateral scattering dose outside the primary beam, but the reported dose difference corresponds to a small spatial deviation (less than 2 mm). It is important to consider this single beam data comparison when the method is extended to more complicated situations, for example when using several beams.
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| 3. |
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| 4. |
- Johansson, S A, et al.
(författare)
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Dosimeter gel and MR imaging for verification of calculated dose distributions in clinical radiation therapy
- 1997
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Ingår i: Acta Oncologica. - 0284-186X. ; 36:3, s. 90-283
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Tidskriftsartikel (refereegranskat)abstract
- A dosimeter gel, based on an agarose gel infused with a ferrous sulphate solution and evaluated in a magnetic resonance scanner, was used for complete verification of calculated dose distributions. Two standard treatment procedures, treatment of cancer in the urinary bladder and treatment of breast cancer after modified radical mastectomy, were examined using pixel-by-pixel and dose volume histogram comparison. The dose distributions calculated with the dose planning system was in very good agreement with the measured ones. However, in the case of the more complicated breast cancer treatment, some discrepancies were found, mainly at the beam abutment region. This may be explained by field displacements errors and by a small limitation of the dose planning utilising small electron beams in this region. The dosimeter gel system have proven to be a useful tool for dosimetry in clinical radiation therapy applications.
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| 5. |
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| 6. |
- Jonsson, Patrik, 1967, et al.
(författare)
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The Use and Applicability of Capacity Planning Methods
- 2002
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Ingår i: Production and Inventory Management Journal. - 0897-8336. ; :3/4, s. 89-95
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Tidskriftsartikel (refereegranskat)abstract
- This study identifies the use of capacity planning methods and analyzes the characteristic modes of application among satisfied users. It is based on data collected from 84 Swedish manufacturing companies. Capacity planning using overall factors and capacity requirements planning are the most common planning methods in Swedish manufacturing industries. Capacity bills is the method with lowest average level of applicability. Satisfied users base capacity requirement determination on objective data and up-date the plans more frequently than dissatisfied users.
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| 7. |
- Mattsson, Niklas, 1979, et al.
(författare)
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CSF biomarker variability in the Alzheimer's Association quality control program
- 2013
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Ingår i: Alzheimers & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 9:3, s. 251-261
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Tidskriftsartikel (refereegranskat)abstract
- Background The cerebrospinal fluid (CSF) biomarkers amyloid beta 1–42, total tau, and phosphorylated tau are used increasingly for Alzheimer's disease (AD) research and patient management. However, there are large variations in biomarker measurements among and within laboratories. Methods Data from the first nine rounds of the Alzheimer's Association quality control program was used to define the extent and sources of analytical variability. In each round, three CSF samples prepared at the Clinical Neurochemistry Laboratory (Mölndal, Sweden) were analyzed by single-analyte enzyme-linked immunosorbent assay (ELISA), a multiplexing xMAP assay, or an immunoassay with electrochemoluminescence detection. Results A total of 84 laboratories participated. Coefficients of variation (CVs) between laboratories were around 20% to 30%; within-run CVs, less than 5% to 10%; and longitudinal within-laboratory CVs, 5% to 19%. Interestingly, longitudinal within-laboratory CV differed between biomarkers at individual laboratories, suggesting that a component of it was assay dependent. Variability between kit lots and between laboratories both had a major influence on amyloid beta 1–42 measurements, but for total tau and phosphorylated tau, between-kit lot effects were much less than between-laboratory effects. Despite the measurement variability, the between-laboratory consistency in classification of samples (using prehoc-derived cutoffs for AD) was high (>90% in 15 of 18 samples for ELISA and in 12 of 18 samples for xMAP). Conclusions The overall variability remains too high to allow assignment of universal biomarker cutoff values for a specific intended use. Each laboratory must ensure longitudinal stability in its measurements and use internally qualified cutoff levels. Further standardization of laboratory procedures and improvement of kit performance will likely increase the usefulness of CSF AD biomarkers for researchers and clinicians.
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| 8. |
- Tumia, N., et al.
(författare)
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Aberdeen Colles' fracture brace as a treatment for Colles' fracture : Amulticentre, prospective, randomised, controlled trial
- 2003
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Ingår i: Journal of Bone and Joint Surgery. - 0301-620X .- 2044-5377. ; 85:1, s. 78-82
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Tidskriftsartikel (refereegranskat)abstract
- We carried out a randomised, prospective, multicentre clinical trial of the treatment of Colles' fractures. A total of 339 patients was placed into two groups, those with minimally displaced fractures not requiring manipulation (151 patients) and those with displaced fractures which needed manipulation (188 patients). Treatment was by either a conventional Colles' plaster cast (a control group) or with a prefabricated functional brace (the Aberdeen Colles' fracture brace). Similar results were obtained in both groups with regard to the reduction and to pain scores but the brace provided better grip strength in the early stages of treatment. This was statistically significant after five weeks for both manipulated and non-manipulated fractures. At the tenth day the results were statistically significant only in manipulated fractures. There was no significant difference in the functional outcome between the two treatment groups. However, younger patients and those with less initial displacement had better functional results.
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