| 1. |
- Kaput, J, et al.
(författare)
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The case for strategic international alliances to harness nutritional genomics for public and personal health
- 2005
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Ingår i: The British journal of nutrition. - : Cambridge University Press (CUP). - 0007-1145 .- 1475-2662. ; 94:5, s. 623-632
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Tidskriftsartikel (refereegranskat)abstract
- Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene–nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient–genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.
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| 2. |
- Baldsiefen, G, et al.
(författare)
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Shears bands in Pb-193
- 1996
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 54:3, s. 1106-1116
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Tidskriftsartikel (refereegranskat)abstract
- Four bands of enhanced dipole transitions, with weak crossovers, have been observed in Pb-195. Three of these bands are connected to the spherical levels. in addition, the spherical level scheme has been extended. The nuclear spectroscopy was done with the early implementation of GAMMASPHERE and HERA arrays of Get detectors. The nucleus Pb-193 was populated in the Yb-174(Mg-24,5n) reaction at beam energies of 129, 131, and 134 MeV. The experimental results are compared to tilted-axis cranking calculations. The systematical behavior of the dipole bands in the heavier odd-A Pb isotopes, Pb-195,Pb-197,Pb-199,Pb-201, is also discussed.
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| 3. |
- McNabb, B, et al.
(författare)
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Using surface velocities to infer ice thickness and bed topography : A case study a Columbia Glacier, Alaska, USA
- 2012
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Ingår i: Journal of Glaciology. - 0022-1430 .- 1727-5652. ; 58:212, s. 1151-1164
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Tidskriftsartikel (refereegranskat)abstract
- Information about glacier volume and ice thickness distribution is essential for manyglaciological applications, but direct measurements of ice thickness can be diffcult and costly. Wepresent a new method that calculates ice thickness via an estimate of ice fux. We solve the familiarcontinuity equation between adjacent fowlines, which decreases the computational time requiredcompared to a solution on the whole grid. We test the method on Columbia Glacier, a large tidewaterglacier in Alaska, USA, and compare calculated and measured ice thicknesses, with favorable results.This shows the potential of this method for estimating ice thickness distribution of glaciers for whichonly surface data are available. We fnd that both the mean thickness and volume of Columbia Glacierwere approximately halved over the period 1957–2007, from 281m to 143m, and from 294km3to134km3, respectively. Using bedrock slope and considering how waves of thickness change propagatethrough the glacier, we conduct a brief analysis of the instability of Columbia Glacier, which leads usto conclude that the rapid portion of the retreat may be nearing an end.
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| 4. |
- McNabb, D P, et al.
(författare)
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Superdeformation in Po-198
- 1996
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 53:2, s. R541-R543
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Tidskriftsartikel (refereegranskat)abstract
- The Yb-174(Si-29,5n) reaction at 148 MeV with thin targets was used to populate high-angular momentum states in Po-198. Resulting gamma rays were observed with Gammasphere. A weakly populated superdeformed band of 10 gamma-ray transitions was found and has been assigned to Po-198. This is the first observation of an SD band in the A approximate to 190 region in a nucleus with Z > 83. The J((2))) of the new band is very similar to those of the yrast SD bands in Hg-194 and Pb-196. The intensity profile suggests that this band is populated through states close to where the SD band crosses the yrast line and the angular momentum at which the fission process dominates.
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| 5. |
- McNabb, R. W., et al.
(författare)
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Alaska tidewater glacier terminus positions, 1948-2012
- 2014
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Ingår i: J GEOPHYS RES-EARTH. - 2169-9003. ; 119:2, s. 153-167
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Tidskriftsartikel (refereegranskat)abstract
- A significant portion of the world's glacier ice drains through tidewater outlets, though much remains unknown about the response to recent climate change of tidewater glaciers. We present a 64 year record of length change for 50 Alaska tidewater glaciers. We use U.S. Geological Survey topographic maps to provide a base length for glaciers before 1970. Using all available cloud-free Landsat images, we manually digitize calving front outlines for each glacier between 1972 and 2012, resulting in a total of more than 10,000 outlines. Tidewater glacier lengths vary seasonally; focusing on the 36 glaciers terminating in tidewater throughout the study period, we find a mean ( standard deviation) seasonal variation of 60 85m a(-1). We use these oscillations to determine the significance of interannual changes in glacier length. All 36 glaciers underwent at least one period (1 year) of significant advance or retreat; 28 glaciers underwent at least one period of both significant advance and retreat. Over the entire period 1948-2012, 24 of these glaciers retreated a total ( uncertainty) of 107.950.29 km, 11 advanced a total of 7.71 +/- 0.20, and one (Chenega Glacier) did not change significantly. Retreats and advances are highly variable in time; several glaciers underwent rapid, short-term retreats of a few years duration. These retreats occurred after large changes in summer sea surface temperature anomalies; further study is needed to determine what triggered these retreats. No coherent regional behavior signal is apparent in the length record, although two subregions show a coherence similar to recent observations in Greenland. Key Points Alaska tidewater glacier length record, 1948-2012 Tidewater glacier retreat not constant in time Some retreats appear to be triggered by changes in ocean temperature
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| 6. |
- McNabb, R. W., et al.
(författare)
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Variations in Alaska tidewater glacier frontal ablation, 1985-2013
- 2015
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Ingår i: Journal of Geophysical Research - Earth Surface. - 2169-9003 .- 2169-9011. ; 120:1, s. 120-136
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Tidskriftsartikel (refereegranskat)abstract
- Our incomplete knowledge of the proportion of mass loss due to frontal ablation (the sum of ice loss through calving and submarine melt) from tidewater glaciers outside of the Greenland and Antarctic ice sheets has been cited as a major hindrance to accurate predictions of global sea level rise. We present a 28 year record (1985-2013) of frontal ablation for 27 Alaska tidewater glaciers (representing 96% of the total tidewater glacier area in the region), calculated from satellite-derived ice velocities and modeled estimates of glacier ice thickness. We account for cross-sectional ice thickness variation, long-term thickness changes, mass lost between an upstream fluxgate and the terminus, and mass change due to changes in terminus position. The total mean rate of frontal ablation for these 27 glaciers over the period 1985-2013 is 15.11 3.63Gta(-1). Two glaciers, Hubbard and Columbia, account for approximately 50% of these losses. The regional total ablation has decreased at a rate of 0.14Gta(-1) over this time period, likely due to the slowing and thinning of many of the glaciers in the study area. Frontal ablation constitutes only approximate to 4% of the total annual regional ablation, but roughly 20% of net mass loss. Comparing several commonly used approximations in the calculation of frontal ablation, we find that neglecting cross-sectional thickness variations severely underestimates frontal ablation.
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