1. |
- Kim, Jae-Young, et al.
(författare)
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Event Horizon Telescope imaging of the archetypal blazar 3C 279 at an extreme 20 microarcsecond resolution
- 2020
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 640
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Tidskriftsartikel (refereegranskat)abstract
- 3C 279 is an archetypal blazar with a prominent radio jet that show broadband flux density variability across the entire electromagnetic spectrum. We use an ultra-high angular resolution technique - global Very Long Baseline Interferometry (VLBI) at 1.3mm (230 GHz) - to resolve the innermost jet of 3C 279 in order to study its fine-scale morphology close to the jet base where highly variable-ray emission is thought to originate, according to various models. The source was observed during four days in April 2017 with the Event Horizon Telescope at 230 GHz, including the phased Atacama Large Millimeter/submillimeter Array, at an angular resolution of ∼20 μas (at a redshift of z = 0:536 this corresponds to ∼0:13 pc ∼ 1700 Schwarzschild radii with a black hole mass MBH = 8 × 108 M⊙). Imaging and model-fitting techniques were applied to the data to parameterize the fine-scale source structure and its variation.We find a multicomponent inner jet morphology with the northernmost component elongated perpendicular to the direction of the jet, as imaged at longer wavelengths. The elongated nuclear structure is consistent on all four observing days and across diffierent imaging methods and model-fitting techniques, and therefore appears robust. Owing to its compactness and brightness, we associate the northern nuclear structure as the VLBI "core". This morphology can be interpreted as either a broad resolved jet base or a spatially bent jet.We also find significant day-to-day variations in the closure phases, which appear most pronounced on the triangles with the longest baselines. Our analysis shows that this variation is related to a systematic change of the source structure. Two inner jet components move non-radially at apparent speeds of ∼15 c and ∼20 c (∼1:3 and ∼1:7 μas day-1, respectively), which more strongly supports the scenario of traveling shocks or instabilities in a bent, possibly rotating jet. The observed apparent speeds are also coincident with the 3C 279 large-scale jet kinematics observed at longer (cm) wavelengths, suggesting no significant jet acceleration between the 1.3mm core and the outer jet. The intrinsic brightness temperature of the jet components are ≤1010 K, a magnitude or more lower than typical values seen at ≥7mm wavelengths. The low brightness temperature and morphological complexity suggest that the core region of 3C 279 becomes optically thin at short (mm) wavelengths.
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2. |
- Marion, G. H., et al.
(författare)
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TYPE IIb SUPERNOVA SN 2011dh : SPECTRA AND PHOTOMETRY FROM THE ULTRAVIOLET TO THE NEAR-INFRARED
- 2014
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Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 781:2, s. 69-
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Tidskriftsartikel (refereegranskat)abstract
- We report spectroscopic and photometric observations of the Type IIb SN 201 ldh obtained between 4 and 34 days after the estimated date of explosion (May 31.5 UT). The data cover a wide wavelength range from 2000 angstrom in the ultraviolet (UV) to 2.4 mu m in the near-infrared (NIR). Optical spectra provide line profiles and velocity measurements of H I, He I, Call, and Fe It that trace the composition and kinematics of the supernova (SN). NIR spectra show that helium is present in the atmosphere as early as 11 days after the explosion. A UV spectrum obtained with the Space Telescope Imaging Spectrograph reveals that the UV flux for SN 2011dh is low compared to other SN IIb. Modeling the spectrum with SYNOW suggests that the UV deficit is due to line blanketing from TinH and Co II. The HI and He I velocities in SN 2011dh are separated by about 4000 km s(-1) at all phases. A velocity gap is consistent with models for a preexplosion structure in which a hydrogen-rich shell surrounds the progenitor. We estimate that the H shell of SN 2011dh is approximate to 8 times less massive than the shell of SN 1993J and approximate to 3 times more massive than the shell of SN 2008ax. Light curves (LCs) for 12 passbands are presented: UVW2, UVM2, UVW1, U, u', B, V, r', i', J, H, and Ks. In the B band, SN 2011dh reached peak brightness of 13.17 mag at 20.0 +/- 0.5 after the explosion. The maximum bolometric luminosity of 1.8 +/- 0.2 x 10(42) erg s(-1) occurred approximate to 22 days after the explosion. NIR emission provides more than 30% of the total bolometric flux at the beginning of our observations, and the NIR contribution increases to nearly 50% of the total by day 34. The UV produces 16% of the total flux on day 4, 5% on day 9, and 1% on day 34. We compare the bolometric LCs of SN 2011dh, SN 2008ax, and SN 1993J. The LC are very different for the first 12 days after the explosions, but all three SN IIb display similar peak luminosities, times of peak, decline rates, and colors after maximum. This suggests that the progenitors of these SN IIb may have had similar compositions and masses, but they exploded inside hydrogen shells that have a wide range of masses. SN 2011dh was well observed, and a likely progenitor star has been identified in preexplosion images. The detailed observations presented here will help evaluate theoretical models for this SN and lead to a better understanding of SN IIb.
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3. |
- Martinez, Hunter A., et al.
(författare)
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Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
- 2024
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Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- Although FOXP3+ regulatory T cells (Treg) depend on IL-2 produced by other cells for their survival and function, the levels of IL-2 in inflamed tissue are low, making it unclear how Treg access this critical resource. Here, we show that Treg use heparanase (HPSE) to access IL-2 sequestered by heparan sulfate (HS) within the extracellular matrix (ECM) of inflamed central nervous system tissue. HPSE expression distinguishes human and murine Treg from conventional T cells and is regulated by the availability of IL-2. HPSE-/- Treg have impaired stability and function in vivo, including in the experimental autoimmune encephalomyelitis (EAE) mouse model of multiple sclerosis. Conversely, endowing monoclonal antibody-directed chimeric antigen receptor (mAbCAR) Treg with HPSE enhances their ability to access HS-sequestered IL-2 and their ability to suppress neuroinflammation in vivo. Together, these data identify a role for HPSE and the ECM in immune tolerance, providing new avenues for improving Treg-based therapy of autoimmunity. Regulatory T cell (Treg) maintenance and function require IL-2, yet this cytokine is only present in low levels in vivo. In this study, the authors demonstrate that that Treg use heparanase to access IL-2 bound to heparan sulfate proteoglycans in the extracellular matrix of inflamed brain tissue in mice.
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