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- Parchenko, Sergii, et al.
(författare)
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Orbital dynamics during an ultrafast insulator to metal transition
- 2020
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Ingår i: Physical Review Research. - : AMER PHYSICAL SOC. - 2643-1564. ; 2:2
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Tidskriftsartikel (refereegranskat)abstract
- We present ultrafast resonant inelastic x-ray scattering (RIXS) experiments performed at the vanadium L edge to track changes in the electronic structure of V2O3, a classical Mott-Hubbard material. The probed orbital excitations within the d shell of the V ion show a sub-ps time response, which evolves at later times to a state that appears electronically indistinguishable from the high-temperature metallic state. For low excitation fluences, a transient recovery or delay is observed, which could be related to a transient dimerization of the V-V bonds. Our results demonstrate the great potential for RIXS spectroscopy to study the ultrafast orbital dynamics in strongly correlated materials.
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- Kuppe, Christoph, et al.
(författare)
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Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures
- 2018
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Ingår i: Nephrology, Dialysis and Transplantation. - : OXFORD UNIV PRESS. - 0931-0509 .- 1460-2385. ; 33:9, s. 1514-1525
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Tidskriftsartikel (refereegranskat)abstract
- Background: Vascular endothelial growth factor A (VEGF) is an essential growth factor during glomerular development and postnatal homeostasis. VEGF is secreted in high amounts by podocytes into the primary urine, back-filtered across the glomerular capillary wall to act on endothelial cells. So far it has been assumed that VEGF back-filtration is driven at a constant rate exclusively by diffusion.Methods: In the present work, glomerular VEGF back-filtration was investigated in vivo using a novel extended model based on endothelial fenestrations as surrogate marker for local VEGF concentrations. Single nephron glomerular filtration rate (SNGFR) and/or local filtration flux were manipulated by partial renal mass ablation, tubular ablation, and in transgenic mouse models of systemic or podocytic VEGF overexpression or reduction.Results: Our study shows positive correlations between VEGF back-filtration and SNGFR as well as effective filtration rate under physiological conditions along individual glomerular capillaries in rodents and humans.Conclusion: Our results suggest that an additional force drives VEGF back-filtration, potentially regulated by SNGFR.
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