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| 2. |
- Almeida, Joao G., et al.
(författare)
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Impact of the 2016 ASE/EACVI recommendations on the prevalence of diastolic dysfunction in the general population
- 2018
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Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 19:4, s. 380-386
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Tidskriftsartikel (refereegranskat)abstract
- Aims: Diastolic dysfunction (DD) is frequent in the general population; however, the assessment of diastolic function remains challenging. We aimed to evaluate the impact of the recent 2016 American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI) recommendations in the prevalence and grades of DD compared with the 2009 guidelines and the Canberra Study Criteria (CSC).Methods and results: Within a population-based cohort, a total of 1000 individuals, aged ≥45 years, were evaluated retrospectively. Patients with previously known cardiac disease or ejection fraction <50% were excluded. Diastolic function was assessed by transthoracic echocardiography. DD prevalence and grades were determined according to the three classifications. The mean age was 62.0 ± 10.5 years and 37% were men. The prevalence of DD was 1.4% (n = 14) with the 2016 recommendations, 38.1% (n = 381) with the 2009 recommendations, and 30.4% (n = 304) using the CSC. The concordance between the updated recommendations and the other two was poor (from k = 0.13 to k = 0.18, P < 0.001). Regarding the categorization in DD grades, none of the 14 individuals with DD by the 2016 guidelines were assigned to Grade 1 DD, 64% were classified as Grade 2, 7% had Grade 3, and 29% had indeterminate grade.Conclusion: The application of the new 2016 ASE/EACVI recommendations resulted in a much lower prevalence of DD. The concordance between the classifications was poor. The updated algorithm seems to be able to diagnose only the most advanced cases.
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| 3. |
- Alves, Ronaldo Adriano, et al.
(författare)
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Flood vulnerability mapping in an urban area with high levels of impermeable coverage in southern Brazil
- 2024
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Ingår i: Regional Environmental Change. - 1436-3798. ; 24:3
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Tidskriftsartikel (refereegranskat)abstract
- Flooding is one of the main social impacts in urban areas, especially in larger, densely impermeable cities. Therefore, developing studies capable of identifying areas that are vulnerable to this type of event is crucial to provide early warning and a quick and effective response to reduce damages. Thus, this study sought to identify areas vulnerable to flood in the Igapó Lake Basin, a densely urbanized area in Lodrina city, southern Brazil. The methodology was based on four main steps: (1) basin characterization, (2) elaboration of the conditioning factors of the flooding by using the analysis hierarchical process (AHP), (3) vulnerability analysis in the GIS environment, (4) and model sensitivity analysis. The parameters considered in this study were as follows: flow concentration, land use, slope, distance from the discharge channel, and altimetry. The proposed methodology has proven to be robust in identifying flood-vulnerable areas. The results revealed that approximately 3.1 km2 (10.3%) of the basin are considered areas of high or very high vulnerability to flood events, affecting many residential buildings, the most abundant land use class in the investigated area. In conclusion, this study sheds light on the intricate interplay between vulnerability to flooding, land use changes, urban development patterns, and resilience measures, offering valuable insights for policymakers and urban planners striving to mitigate the impacts of extreme weather events.
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| 4. |
- Beal, Jacob, et al.
(författare)
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Robust estimation of bacterial cell count from optical density
- 2020
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Ingår i: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
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Tidskriftsartikel (refereegranskat)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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| 5. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 6. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 7. |
- de Almeida, Daniela S., et al.
(författare)
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Genotoxic effects of daily personal exposure to particle mass and number concentrations on buccal cells
- 2018
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Ingår i: Atmospheric Environment. - : Elsevier BV. - 1352-2310. ; 176, s. 148-157
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study is to assess personal exposure to Particle Number Concentrations (PNC) in four size ranges between 0.3 and 10 μm, and particulate matter (PM1; PM2.5; PM4; PM10) in order to evaluate possible genotoxic effects through a comet assay in buccal cells. A convenience cohort of 30 individuals from a Brazilian medium-sized city was selected. These individuals aged between 20 and 61 and worked in typical job categories (i.e., administrative, commerce, education, general services and transport). They were recruited to perform personal exposure measurements during their typical daily routine activities, totaling 240 h of sampling. The 8-h average mass concentrations in air for volunteers ranged from 2.4 to 31.8 μg m−3 for PM1, 4.2–45.1 μg m−3 for PM2.5, 7.9–66.1 μg m−3 for PM4 and from 23.1 to 131.7 μg m−3 for PM10. The highest PNC variation was found for 0.3–0.5 range, between 14 and 181 particles cm−3, 1 to 14 particles cm−3 for the 0.5–1.0 range, 0.2 to 2 particles cm−3 for the 1.0–2.5 range, and 0.06 to 0.7 particles cm−3 for the 2.5–10 range. Volunteers in the ‘education’ category experienced the lowest inhaled dose of PM2.5 as opposed to those involved in ‘commercial‘ activities with the highest doses for PM10 (1.63 μg kg−1 h−1) and PM2.5 (0.61 μg kg−1 h−1). The predominant cause for these high doses was associated with the proximity of the workplace to the street and vehicle traffic. The comet assay performed in buccal cells indicated that the volunteers in ‘commerce’ category experienced the highest damage to their DeoxyriboNucleic Acid (DNA) compared with the control category (i.e. ‘education’). These results indicate the variability in personal exposure of the volunteers in different groups, and the potential damage to DNA was much higher for those spending time in close proximity to the vehicle sources (e.g. commercial services) leading to exposure to a higher fraction of fine particles. This study builds understanding on the exposure of people in different job categories, and provide policy makers with useful information to tackle this neglected issue.
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| 8. |
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| 9. |
- Dinkel, Holly, et al.
(författare)
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Multi-Agent 3D Map Reconstruction and Change Detection in Microgravity with Free-Flying Robots
- 2023
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Ingår i: Proceedings of the International Astronautical Congress, IAC. - 0074-1795. ; 2023-October
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Konferensbidrag (refereegranskat)abstract
- Assistive free-flyer robots autonomously caring for future crewed outposts-such as NASA's Astrobee robots on the International Space Station (ISS)-must be able to detect day-to-day interior changes to track inventory, detect and diagnose faults, and monitor the outpost status. This work presents a framework for multi-agent cooperative mapping and change detection to enable robotic maintenance of space outposts. One agent is used to reconstruct a 3D model of the environment from sequences of images and corresponding depth information. Another agent is used to periodically scan the environment for inconsistencies against the 3D model. Change detection is validated after completing the surveys using real image and pose data collected by Astrobee robots in a ground testing environment and from microgravity aboard the ISS. This work outlines the objectives, requirements, and algorithmic modules for the multi-agent reconstruction system, including recommendations for its use by assistive free-flyers aboard future microgravity outposts
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| 10. |
- Fujita, Thais, et al.
(författare)
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Simulating Discharge in a Non-Dammed River of Southeastern South America Using SWAT Model
- 2022
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Ingår i: Water. - : MDPI AG. - 2073-4441. ; 14:3
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Tidskriftsartikel (refereegranskat)abstract
- Within a single region, it is possible to identify opposite changes in flow production. This proved to be the case for several basins in southeastern South America. It remains challenging to the causes this behavior and whether changes in streamflow will continue at current levels or decline in the coming decades. In this study, we used the Soil Water Assessment Tool to simulate monthly river discharge in the Ivaí River Basin, an unregulated medium-sized catchment and tributary of the Upper Paraná River Basin. After calibration, the simulated flow regime for the five streamflow stations based on the Nash-Sutcliffe Efficiency index (NSE) rated four of the streamflow stations Very Good (NSE between 0.86 and 0.89) and only one in the Good index (0.70). The overall flow behavior was well represented, although an underestimation was identified in four monitoring stations. Through assessment of its functionality and limitations in terms of specific flow duration curves percentages, the calibrated model could provide (to managers) the reliability needed for a realistic intervention. The results of this study may assist managers and support public policies for the use of water resources at the Ivaí River basin.
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