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Sökning: WFRF:(Moya Cristobal)

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1.
  • Breznau, Nate, et al. (författare)
  • Observing many researchers using the same data and hypothesis reveals a hidden universe of uncertainty
  • 2022
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 119:44
  • Tidskriftsartikel (refereegranskat)abstract
    • This study explores how researchers analytical choices affect the reliability of scientific findings. Most discussions of reliability problems in science focus on systematic biases. We broaden the lens to emphasize the idiosyncrasy of conscious and unconscious decisions that researchers make during data analysis. We coordinated 161 researchers in 73 research teams and observed their research decisions as they used the same data to independently test the same prominent social science hypothesis: that greater immigration reduces support for social policies among the public. In this typical case of social science research, research teams reported both widely diverging numerical findings and substantive conclusions despite identical start conditions. Researchers expertise, prior beliefs, and expectations barely predict the wide variation in research outcomes. More than 95% of the total variance in numerical results remains unexplained even after qualitative coding of all identifiable decisions in each teams workflow. This reveals a universe of uncertainty that remains hidden when considering a single study in isolation. The idiosyncratic nature of how researchers results and conclusions varied is a previously underappreciated explanation for why many scientific hypotheses remain contested. These results call for greater epistemic humility and clarity in reporting scientific findings.
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2.
  • García, Ariel, et al. (författare)
  • Dilute sulphuric acid pretreatment and enzymatic hydrolysis of Jatropha curcas fruit shells for ethanol production
  • 2014
  • Ingår i: Industrial crops and products (Print). - : Elsevier. - 0926-6690 .- 1872-633X. ; 53, s. 148-153
  • Tidskriftsartikel (refereegranskat)abstract
    • Abstract Jatropha curcas is a promising source of oil for the biodiesel industry, and the shells of its fruits could be considered for ethanol production. In this work, the composition of J. curcas shells is investigated, and the potential of dilute-sulphuric acid pretreatment for improving the enzymatic hydrolysis of cellulose is evaluated. A Box–Behnken experimental design was used for assessing the effect of temperature (110–150 °C), H2SO4 concentration (0.5–2.5%) and pretreatment time (15–45 min) on the formation of sugars during pretreatment and on the enzymatic conversion of cellulose. Cellulose conversions above 80% were achieved both in the separated enzymatic hydrolysis and in the simultaneous saccharification and fermentation of the pretreated materials. Optimal SSF conversions were predicted for pretreatments at low temperature (136 °C) and moderate acid concentrations (1.5%) and reaction time (30 min). The inclusion of an extraction step prior to the pretreatment revealed a further improvement of the enzymatic conversion of cellulose.
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