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Sökning: WFRF:(Mulligan Geoff)

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1.
  • Durvy, Mathilde, et al. (författare)
  • Making sensor networks IPv6 ready
  • 2008. - 1
  • Ingår i: Proceedings of the Sixth ACM Conference on Networked Embedded Sensor Systems (ACM SenSys 2008).
  • Konferensbidrag (refereegranskat)abstract
    • With emerging IPv6-based standards such as 6LowPAN and ISA- 100a, full IPv6 sensor networks are the next major step. With millions of deployed embedded IPv6 devices, interoperability is of major importance, both within the sensor networks and between the sensors and the Internet hosts. We present uIPv6, the first IPv6 stack for memory-constrained devices that passes all Phase-1 IPv6 Ready certification tests. This is an important step for end-to-end interoperability between IPv6 sensors and any IPv6 capable device. To allow widespread community adoption, we release uIPv6 under a permissive open source license that allows both commercial and non-commercial use.
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2.
  • Durvy, Mathilde, et al. (författare)
  • Making sensor networks ipv6 ready
  • 2008
  • Ingår i: In Proceedings of the Sixth ACM Conference on Networked Embedded Sensor Systems (ACM SenSys 2008), Raleigh, North Carolina, USA, November 2008..
  • Konferensbidrag (refereegranskat)
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3.
  • Lawrenson, Kate, et al. (författare)
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
  • 2016
  • Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7
  • Tidskriftsartikel (refereegranskat)abstract
    • A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk.
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6.
  • Wells, Geoff J., et al. (författare)
  • Hundreds of millions of people in the tropics need both wild harvests and other forms of economic development for their well-being
  • 2024
  • Ingår i: One Earth. - 2590-3330 .- 2590-3322. ; 7:2, s. 311-324
  • Tidskriftsartikel (refereegranskat)abstract
    • Local access to “wild,” common-pool terrestrial and aquatic resources is being diminished by global resource demand and large-scale conservation interventions. Many theories suggest the well-being of wild harvesters can be supported through transitions to other livelihoods, improved infrastructure, and market access. However, new theories argue that such benefits may not always occur because they are context dependent and vary across dimensions of well-being. We test these theories by comparing how wild harvesting and other livelihoods have been associated with food security and life satisfaction in different contexts across ∼10,800 households in the tropics. Wild harvests coincided with high well-being in remote, asset-poor, and less-transformed landscapes. Yet, overall, well-being increased with electrical infrastructure, proximity to cities, and household capitals. This provides large-scale confirmation of the context dependence of nature’s contributions to people, and suggests a need to maintain local wild resource access while investing in equitable access to infrastructure, markets, and skills.
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  • Resultat 1-6 av 6

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