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Sökning: WFRF:(Murty K.V.G.K.)

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1.
  • Lorén, Anders, 1974, et al. (författare)
  • Feasibility of quantitative determination of doxorubicin with surface-enhanced Raman spectroscopy
  • 2001
  • Ingår i: Journal of Raman Spectroscopy. - : Wiley. - 0377-0486 .- 1097-4555. ; 32:11, s. 971-974
  • Tidskriftsartikel (refereegranskat)abstract
    • Surface-enhanced Raman spectroscopy (SERS) was performed using excitation at 488 nm in a blood plasma-doxorubicin-silver colloid system. With a blood plasma content of 1%, a partial least-squares calibration of the doxorubicin was made in the 10-750 nM range. Predictions for a test set generated a root mean square error of prediction of 70 nM. The use of SERS and chemometrics in complex systems made it possible to use the highly informative Raman signals even at low concentrations without the need for sample pretreatment such as extraction. Copyright © 2001 John Wiley & Sons, Ltd.
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2.
  • Prikulis, J., et al. (författare)
  • Large-area Topography Analysis and Near-field Raman Spectroscopy using Bent Fibre Probes
  • 2003
  • Ingår i: Journal of Microscopy. - : Wiley. - 0022-2720 .- 1365-2818. ; 210:3, s. 269-273
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a method for combined far-field Raman imaging, topography analysis and near-field spectroscopy. Surface-enhanced Raman spectra of Rhodamine 6G (R6G) deposited on silver nanoparticles were recorded using a bent fibre aperture-type near-field scanning optical microscope (NSOM) operated in illumination mode. Special measures were taken to enable optical normal-force detection for control of the tip–sample distance. Comparisons between far-field Raman images of R6G-covered Ag particle aggregates with topographic images recorded using atomic force microscopy (AFM) indicate saturation effects due to resonance excitation.
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