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Sökning: WFRF:(Musacchio Fabrizio)

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1.
  • Musacchio, Fabrizio, et al. (författare)
  • Morphology of Ganymede's FUV auroral ovals
  • 2017
  • Ingår i: Journal of Geophysical Research - Space Physics. - : AMER GEOPHYSICAL UNION. - 2169-9380 .- 2169-9402. ; 122:3, s. 2855-2876
  • Tidskriftsartikel (refereegranskat)abstract
    • We study the morphology of Ganymede's FUV aurora by analyzing spectral images obtained over the past two decades by the Space Telescope Imaging Spectrograph on board the Hubble Space Telescope. The observations cover the eastern and western elongation as well as various magnetic latitudes of Ganymede within the Jovian plasma sheet. We find both asymmetries in the spatial distribution of auroral brightness on the observed moon disk and temporal variation correlated to Ganymede's changing magnetic latitude. The total disk brightness is on average 1.42 +/- 0.07 times brighter on the leading side (95.4 +/- 2.1R) than on the trailing side (67.2 +/- 2.9R). The brightness ratio of the sub-Jovian hemisphere to the anti-Jovian hemisphere is 1.81 +/- 0.06 on the leading side and 1.41 +/- 0.14 on the trailing side, respectively. Inside the Jovian current sheet, the brightness of the auroral ovals increases by a factor of 1.45 +/- 0.02 on the leading side and decreases by a factor of 0.80 +/- 0.02 on the trailing side. At the current sheet center, the auroral ovals shift 4.1 degrees +/- 0.7 degrees latitude toward Ganymede's planetographic equator on the leading side and 2.9 degrees +/- 1.5 degrees toward the poles on the trailing side. Both effects, the variation of brightness and the movement of the ovals are correlated to a stronger interaction of Jupiter's magnetospheric plasma with Ganymede's minimagnetosphere inside the current sheet. Finally, we calculate the latitudinal difference of the northern and southern ovals from Ganymede's magnetic equator. The result suggests a farther westward orientation of Ganymede's dipole magnetic moment at approximately 47 degrees + 58 degrees/-43 degrees west longitude compared to previous estimates.
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2.
  • Poll, Stefanie, et al. (författare)
  • Memory trace interference impairs recall in a mouse model of Alzheimer’s disease
  • 2020
  • Ingår i: Nature Neuroscience. - : Springer. - 1097-6256 .- 1546-1726. ; 23:8, s. 952-958
  • Tidskriftsartikel (refereegranskat)abstract
    • In Alzheimer’s disease (AD), hippocampus-dependent memories underlie an extensive decline. The neuronal ensemble encoding a memory, termed engram, is partially recapitulated during memory recall. Artificial activation of an engram can restore memory in a mouse model of early AD, but its fate and the factors that render the engram nonfunctional are yet to be revealed. Here, we used repeated two-photon in vivo imaging to analyze fosGFP transgenic mice (which express enhanced GFP under the Fos promoter) performing a hippocampus-dependent memory task. We found that partial reactivation of the CA1 engram during recall is preserved under AD-like conditions. However, we identified a novelty-like ensemble that interfered with the engram and thus compromised recall. Mimicking a novelty-like ensemble in healthy mice was sufficient to affect memory recall. In turn, reducing the novelty-like signal rescued the recall impairment under AD-like conditions. These findings suggest a novel mechanistic process that contributes to the deterioration of memories in AD.
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