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| 2. |
- Forrest, ARR, et al.
(författare)
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A promoter-level mammalian expression atlas
- 2014
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 507:7493, s. 462-
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Tidskriftsartikel (refereegranskat)
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| 3. |
- Müller, T D, et al.
(författare)
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Ghrelin.
- 2015
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Ingår i: Molecular metabolism. - : Elsevier BV. - 2212-8778. ; 4:6, s. 437-60
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Tidskriftsartikel (refereegranskat)abstract
- The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism.
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| 4. |
- Noguchi, S, et al.
(författare)
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FANTOM5 CAGE profiles of human and mouse samples
- 2017
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Ingår i: Scientific data. - : Springer Science and Business Media LLC. - 2052-4463. ; 4, s. 170112-
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Tidskriftsartikel (refereegranskat)abstract
- In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.
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| 5. |
- Nakamura, M., et al.
(författare)
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Experimental verification of SDN/NFV in integrated mmwave access and mesh backhaul networks
- 2021
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Ingår i: IEICE transactions on communications. - : Institute of Electronics, Information and Communication, Engineers, IEICE. - 0916-8516 .- 1745-1345. ; E104B:3, s. 217-228
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, a Proof-of-Concept (PoC) architecture is constructed, and the effectiveness of mmWave overlay heterogeneous network (HetNet) with mesh backhaul utilizing route-multiplexing and Multi-access Edge Computing (MEC) utilizing prefetching algorithm is verified by measuring the throughput and the download time of real contents. The architecture can cope with the intensive mobile data traffic since data delivery utilizes multiple backhaul routes based on the mesh topology, i.e. route-multiplexing mechanism. On the other hand, MEC deploys the network edge contents requested in advance by nearby User Equipment (UE) based on pre-registered context information such as location, destination, demand application, etc. to the network edge, which is called prefetching algorithm. Therefore, mmWave access can be fully exploited even with capacity-limited backhaul networks by introducing the proposed algorithm. These technologies solve the problems in conventional mmWave HetNet to reduce mobile data traffic on backhaul networks to cloud networks. In addition, the proposed architecture is realized by introducing wireless Software Defined Network (SDN) and Network Function Virtualization (NFV). In our architecture, the network is dynamically controlled via wide-coverage microwave band links by which UE's context information is collected for optimizing the network resources and controlling network infrastructures to establish backhaul routes and MEC servers. In this paper, we develop the hardware equipment and middleware systems, and introduce these algorithms which are used as a driver of IEEE802.11ad and open source software. For 5G and beyond, the architecture integrated in mmWave backhaul, MEC and SDN/NFV will support some scenarios and use cases.
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| 6. |
- Numata, N, et al.
(författare)
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Associations between autism spectrum disorder and eating disorders with and without self-induced vomiting: an empirical study
- 2021
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Ingår i: Journal of eating disorders. - : Springer Science and Business Media LLC. - 2050-2974. ; 9:1, s. 5-
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundAlthough approximately 23% of anorexia nervosa (AN) patients have concomitant autism spectrum disorder (ASD), it is clinically difficult to determine ASD coexistence in patients with eating disorders. Restrictive AN is more common in younger patients and self-induced vomiting usually appears during adolescence/young adulthood, in order to prevent gaining weight caused by overeating. However, some patients are tolerant of weight gain even if they start overeating. It is important to understand the essential difference between those who vomit and those who do not vomit. In this study, we hypothesised that the absence of self-induced vomiting may be associated with the presence of ASD and aimed to assess the presence of ASD traits in each eating disorder (EDs). Clarifying this association helps to consider the coexistence of ASD in the clinical setting and can lead to the next detailed ASD evaluation, and as a result, helps to determine the appropriate treatment and support individually.MethodsWe retrospectively evaluated 43 females aged 15–45 years who attended Chiba University Hospital between 2012 and 2016 using the Eating Disorder Examination Questionnaire (EDE-Q) and Autism-Spectrum Quotient (AQ) to quantify the severity of the EDs and to identify whether ASD traits were present.ResultsThere was no difference in the AQ score between bingeing-purging type AN and restricting type AN. However, there was significant difference in the AQ score between bulimia nervosa and binge EDs (BED). Of the 4 ED subtypes, BED had the highest ASD traits. The non-vomiting group with illness duration < 4 years had a significantly higher AQ communication score than the vomiting group with illness duration ≥4 years.ConclusionsThere was a difference in the AQ score by the presence or absence of self-induced vomiting. The results of this study suggest an association between high scores on AQ and non-vomiting. Thus, evaluation of patients for the absence of self-induced vomiting while assessing them for EDs may help us to understand the association with ASD traits.
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| 7. |
- Terracciano, A, et al.
(författare)
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National character does not reflect mean personality trait levels in 49 cultures
- 2005
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 310:5745, s. 96-100
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Tidskriftsartikel (refereegranskat)abstract
- Most people hold beliefs about personality characteristics typical of members of their own and others' cultures. These perceptions of national character may be generalizations from personal experience, stereotypes with a "kernel of truth," or inaccurate stereotypes. We obtained national character ratings of 3989 people from 49 cultures and compared them with the average personality scores of culture members assessed by observer ratings and self-reports. National character ratings were reliable but did not converge with assessed traits. Perceptions of national character thus appear to be unfounded stereotypes that may serve the function of maintaining a national identity.
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| 8. |
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| 9. |
- Hjerten, S, et al.
(författare)
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Gels mimicking antibodies in their selective recognition of proteins
- 1997
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Ingår i: CHROMATOGRAPHIA. - : VIEWEG. - 0009-5893. ; 44:5-6, s. 227-234
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- In a previous paper we presented preliminary experiments aimed at the preparation of gel particles with the property to recognize selectively some particular protein (hemoglobin, cytochrome C, transferrin) [1]. Using the same method we show in this articl
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| 10. |
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