| 1. |
- Nijkamp, P., et al.
(författare)
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Towards a regional science academy : A manifesto
- 2016
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Ingår i: Region. - : European Regional Science Association. - 2409-5370. ; 3:1, s. R1-R16
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Tidskriftsartikel (refereegranskat)abstract
- This Manifesto provides a joint proposal to create a Regional Science Academy as a think-tank support platform for a strategic development of the spatial sciences. The Regional Science Academy is a strategic spatial knowledge catalyst: it acts as a global intellectual powerhouse for new knowledge network initiatives and scholarly views on regions and cities as vital centrepieces of interconnected spatial systems. This contribution highlights its role and presents various activity plans.
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| 2. |
- Nijkamp, J. F., et al.
(författare)
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De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology
- 2012
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Ingår i: Microbial Cell Factories. - : Springer Science and Business Media LLC. - 1475-2859. ; 11, s. Article Number: 36-
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Tidskriftsartikel (refereegranskat)abstract
- Saccharomyces cerevisiae CEN.PK 113-7D is widely used for metabolic engineering and systems biology research in industry and academia. We sequenced, assembled, annotated and analyzed its genome. Single-nucleotide variations (SNV), insertions/deletions (indels) and differences in genome organization compared to the reference strain S. cerevisiae S288C were analyzed. In addition to a few large deletions and duplications, nearly 3000 indels were identified in the CEN.PK113-7D genome relative to S288C. These differences were overrepresented in genes whose functions are related to transcriptional regulation and chromatin remodelling. Some of these variations were caused by unstable tandem repeats, suggesting an innate evolvability of the corresponding genes. Besides a previously characterized mutation in adenylate cyclase, the CEN. PK113-7D genome sequence revealed a significant enrichment of non-synonymous mutations in genes encoding for components of the cAMP signalling pathway. Some phenotypic characteristics of the CEN. PK113-7D strains were explained by the presence of additional specific metabolic genes relative to S288C. In particular, the presence of the BIO1 and BIO6 genes correlated with a biotin prototrophy of CEN. PK113-7D. Furthermore, the copy number, chromosomal location and sequences of the MAL loci were resolved. The assembled sequence reveals that CEN. PK113-7D has a mosaic genome that combines characteristics of laboratory strains and wild-industrial strains.
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| 3. |
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| 4. |
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| 5. |
- Arribas-Bel, D., et al.
(författare)
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Cyber Cities : Social Media as a Tool for Understanding Cities
- 2015
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Ingår i: Applied Spatial Analysis and Policy. - : Springer Science+Business Media B.V.. - 1874-463X .- 1874-4621. ; 8:1, s. 231-247
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Tidskriftsartikel (refereegranskat)abstract
- ‘Big’ urban data are increasingly becoming accessible for scientific research and policy use. They may enhance the intelligence that is needed for understanding and mapping out social connectivity phenomena (in the sense of Jane Jacobs) in modern smart cities. The present paper aims to highlight and demonstrate the rich potential of information based on digital technology in modern cities. As a case study example of the power of social media data as a support tool in smart cities, we consider Twitter data in the municipality of Amsterdam. We use machine learning techniques to identify temporal patterns that we then relate back to their spatial dimension, effectively connecting the digital with physical aspect of cities. We also show that analysis of geo-referenced tweets can shed significant light on physical aspects of the city and on the spatial distribution of urban functions.
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| 6. |
- Banica, A, et al.
(författare)
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Natural disasters as a development opportunity : a spatial economic resilience interpretation
- 2020
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Ingår i: Jahrbuch für Regional Wissenschaft. - : Springer. - 0173-7600 .- 1613-9836.
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Tidskriftsartikel (refereegranskat)abstract
- Natural disasters are usually regarded as damage factors causing high private and social costs. Notwithstanding the incontestable validity of this premise, natural disasters do not necessarily lead to a structural deprivation of the area affected. Recent studies have clearly shown that in the long run one may even observe positive socio-economic effects (‘blessings in disguise’). This paper investigates this challenging proposition by developing a risk-disaster-opportunity framework for a territorial system, and by analysing the socio-economic impacts of natural shocks from a resilience perspective. This is inter alia done by designing a typology of natural disasters, and by presenting a systematic classification of long-range impacts. An empirical test of the above proposition of positive recovery effects of natural disasters is carried out by using, in particular, long-term data from the worldwide EM-DAT database. The attention is then focussed on positive feedback loops in spatial systems that are affected by a natural perturbation. Various case studies (USA, China, Haiti, Chile, Japan) are undertaken in order to test the existence of long-term ‘blessings in disguise’ effects, using in particular the HDI-index. In various cases, such positive effects appear to exist, depending on the effectiveness of public management of natural disaster phenomena.
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| 7. |
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| 8. |
- Gheasi, M., et al.
(författare)
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A meta-analysis of human health differences in urban and rural environments
- 2019
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Ingår i: Letters in spatial and resource sciences. - : Springer Verlag. - 1864-4031 .- 1864-404X. ; 12:3, s. 167-186
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Tidskriftsartikel (refereegranskat)abstract
- Human health outcomes are known to be affected not only by individual physical and socio-economic status, but also by external environmental conditions, as well as by place-based economic and geographical circumstances. In recent decades, a large number of studies have addressed the background of differences in health outcomes between rural and urban areas. Are rural ways of living healthier than urban ways of living? This has led to a wealth of studies on human health and the geographical differences of living and working. The effects of regional or urban characteristics on health outcomes are often inconsistent among different studies/countries. An important factor that seems to be important is the ambiguous definition of both health and urbanism, as well as the presence of intra-regional heterogeneity (e.g. inner-city areas). In the present study, we conduct a systematic review of the existing literature on space and health indicators, based on a broad, but concise overview of the underlying mechanisms involved. Next, we provide a quantitative research synthesis with the help of a meta-analysis of published studies on self-rated/self-reported physical health conditions in rural and urban areas. The results from our meta-analytical regression analysis indicate that there is not a clearly convincing difference between rural and urban areas; however, people in rural areas appear to rate themselves slightly healthier than their urban counterparts. In addition, we observe that self-rated/reported fair/poor health is also highly dependent on a number of personal and socio-economic factors; from a personal perspective, education, addiction, physical activity, and duration of residence appear to play a significant role, while, from a socio-economic perspective, in particular, community predictor measures (e.g. gross domestic product, population, unemployment rate) appear to exert a substantial influence.
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| 9. |
- Girard, L. F., et al.
(författare)
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‘Science of the city’ : Towards a higher quality of urban life
- 2017
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Ingår i: Quality Innovation Prosperity. - : Technical University of Kosice. - 1335-1745 .- 1338-984X. ; 21:1, s. 1-8
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Tidskriftsartikel (refereegranskat)abstract
- Cities have in the course of history become the dominant geographic settlement pattern all over the world; we live in the ‘urban century’. Cities integrate all dimensions of modern life, ranging from socio-economic to technological aspects. The organisation of such complex entities calls for a more integrative an inclusive scientific analysis and understanding of urban systems. The aim of the Special Issue Science of the City: Towards a Higher Quality of Urban Life, is to offer a synthesis of the contributions from the Advanced Brainstorm Carrefour (ABC) meeting, held on March 22-23, 2016 in Naples, bringing together experts who have provided a significant contribution to a fundamental reflection on the roots and effects of the modern city.
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| 10. |
- Hårsman Wahlström, Marie, 1970-, et al.
(författare)
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Planning Cities4People–A body and soul analysis of urban neighbourhoods
- 2020
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Ingår i: Public Management Review. - : Informa UK Limited. - 1471-9037 .- 1471-9045. ; 22:5, s. 687-700
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Tidskriftsartikel (refereegranskat)abstract
- There is a growing interest among urban planners in identifying and reinforcing key features that differentiate a city from others. At a local level, neighbourhoods are increasingly positioned and branded, based on their distinguishing characteristics. Against this background this paper aims to contribute to a better governance of cities and urban neighbourhoods by pinpointing the determinants of citizens’ perceptions of urban quality of life. A conceptual model on neighbourhood love, comprising both body and soul constituents, is developed and empirically tested. The results show that the residents’ ‘love’ for their neighbourhood is significantly related to both its material and immaterial amenities.
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