| 1. |
- Nilsson, Inga-Lill, 1960-, et al.
(författare)
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Öppen vetenskap och forskningsbibliotekens nya roller
- 2022
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Ingår i: Bidrag från universitetspedagogisk konferens 2021. - Karlstad : Karlstads universitet. - 9789178672974 - 9789178673087 ; , s. 109-127
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Bokkapitel (refereegranskat)abstract
- Öppen vetenskap eller Open Science innebär att alla moment och resultat i forskningen görs fritt tillgängliga via internet. Genom den digitala teknikens utveckling har öppen vetenskap blivit en global rörelse. Detta gäller främst tillgången till vetenskapliga publikationer och forskningsdata. Forskningsresultat som är öppna och tillgängliga även utanför forskarsamhället får en ökad användning och nytta i samhället. Hela forskningsprocessen blir mer transparant när forskningen snabbt finns tillgänglig online och fler kan ta aktiva roller eller inleda samarbeten. Även öppna undervisningsresurser som skapas vid universiteten, ofta kallade OER (Open Educational Resources) ingår i det övergripande begreppet Open Science. De har stor betydelse i högre utbildning och kan vara viktiga resurser i det livslånga lärandet (Eellend, 2017). Sättet att publicera och sprida information eller litteratur förändras snabbt och ställer höga krav på lärarna att kunna navigera mellan olika litteraturresurser och veta hur man hittar och får använda sig av bibliotekets databaser, fria forskningsresurser och övriga fria resurser (Creelman, 2011). Biblioteken har genom sin traditionella uppgift, att tillgängliggöra information och att ansvara för publiceringsstöd, fått en allt viktigare uppgift som samordnare av olika nya tjänster som referenshanteringssystem, bibliometri, upphovsrätt mm. Tyvärr saknar ofta lärare och forskare vetskap om vilka nya tjänster och kompetenser som finns på forskningsbiblioteken. Förutom att tillhandahålla egna litteraturresurser och databaser har biblioteken stor kunskap om öppen vetenskap och öppna lärresurser och kan bistå studenter och lärare i att söka och använda fritt material (Smith & Lee, 2017). Nedstängningen av universitet och bibliotek under coronapandemin har aktualiserat frågan om öppna lärresurser.
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| 2. |
- Abbasi, Maisam, et al.
(författare)
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Who controls logistics emissions? Challenges in making fragmented supply chains environmentally sustainable from a logistics service provider's perspective
- 2014
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Ingår i: Proceedings of the 26th Conference of the Nordic Logistics Research Network: NOFOMA 2014. - 9788799743308 ; , s. 201-218
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Konferensbidrag (refereegranskat)abstract
- Purpose The purpose of this article is to explore the environmental impact of Logistics Service Provider (LSP) activities in the light of increased customer attention and fragmentation of the industry. We try to answer the question, to what extent the LSPs can actually monitor the environmental impact of logistics activities in the supply chain? Design/methodology/approach The methodology of this paper is a literature review, a qualitative interview survey, and three case studies. A framework on sustainability challenges in supply chains derived from the literature is used to structure and analyze the findings. Findings Our findings reveal that despite ambitious environmental schemes communicated by several LSPs, LSPs exert very little control over the actual emissions created from their transport operations. Furthermore, it is clear from this study that any real interest in environmental solutions that impact the cost and time requirements from customers of logistics services are not yet a reality. Research limitations/implications This paper implies that LSP sustainability cannot be investigated in isolation if a company does not manage proprietary resources. Practical implications Our findings imply that environmental policies between different LSPs appear similar, but in practice differs, which stresses the importance of follow-up control by environmentally aware logistics service buyers. Originality/value This paper represents a novel approach as to how LSP environmental policies should be viewed.
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| 3. |
- Andersson, Christian, et al.
(författare)
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Mobila strategier. En rapport från arbetsgruppen Nya medier
- 2007
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Utredningens fokus skall ligga på Bibliotek och ITs framtida hantering av mobila tjänster, läsplattor, ljud och bildfiler i olika format och dess tillgängliggöranden, MP3-spelare, dator- och TV-spel. Texten kan ses som en omvärldsanalys av möjligheter och scenarion kring arbetet med ovan nämnda tjänster och produkter. Förhoppningen är att texten ska peka på möjliga fokus för organisationen, stimulera till idéproduktion och vara avstampen för nya arbetstrupper för Bibliotek och IT.
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| 4. |
- Andres, Sonke, et al.
(författare)
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Type I Restriction-Modification Loci Reveal High Allelic Diversity in Clinical Helicobacter pylori Isolates
- 2010
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Ingår i: Helicobacter. - : Wiley. - 1083-4389 .- 1523-5378. ; 15:2, s. 114-125
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Tidskriftsartikel (refereegranskat)abstract
- Background: A remarkable variety of restriction-modification (R-M) systems is found in Helicobacter pylori. Since they encompass a large portion of the strain-specific H. pylori genes and therefore contribute to genetic variability, they are suggested to have an impact on disease outcome. Type I R-M systems comprise three different subunits and are the most complex of the three types of R-M systems. Aims: We investigated the genetic diversity and distribution of type I R-M systems in clinical isolates of H. pylori. Material and methods: Sixty-one H. pylori isolates from a Swedish hospital based case-control study and 6 H. pylori isolates of a Swedish population-based study were analyzed using polymerase chain reaction for the presence of the three R-M systems' subunits. Representative gene variants were sequenced. Results: Although the hsdM and hsdR genes appeared conserved in our clinical H. pylori isolates, the sequences of the hsdS loci were highly variable. Despite their sequence diversity, the genes per se were present at high frequencies. We identified a number of novel allelic hsdS variants, which are distinct from corresponding hsdS loci in the sequenced H. pylori strains 26695, J99 and HPAG1. In analyses of paired H. pylori isolates, obtained from the same individuals with a 4-year interval, we observed genetic modifications of hsdS genes in patients with atrophic gastric mucosa. Discussion: We propose that the genetic variability of hsdS genes in a bacterial population will give rise to new specificities of these enzymes, which might lead to adaptation to an ever-changing gastric environment.
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| 5. |
- Anh, Nhi, et al.
(författare)
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High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing
- 2018
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 13:3
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Tidskriftsartikel (refereegranskat)abstract
- The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis-a low-resolution genome-wide chromosome analysis-is still the gold standard, it often needs to be complemented with other methods to increase resolution. To evaluate the feasibility and applicability of mate pair whole genome sequencing (MP-WGS) to detect structural chromosomal rearrangements in the diagnostic setting, we sequenced ten bone marrow samples from leukemia patients with recurrent rearrangements. Samples were selected based on cytogenetic and FISH results at leukemia diagnosis to include common rearrangements of prognostic relevance. Using MP-WGS and in-house bioinformatic analysis all sought rearrangements were successfully detected. In addition, unexpected complexity or additional, previously undetected rearrangements was unraveled in three samples. Finally, the MP-WGS analysis pinpointed the location of chromosome junctions at high resolution and we were able to identify the exact exons involved in the resulting fusion genes in all samples and the specific junction at the nucleotide level in half of the samples. The results show that our approach combines the screening character from karyotype analysis with the specificity and resolution of cytogenetic and molecular methods. As a result of the straightforward analysis and high-resolution detection of clinically relevant rearrangements, we conclude that MP-WGS is a feasible method for routine leukemia diagnostics of structural chromosomal rearrangements.
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| 6. |
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| 7. |
- Bodén, Ida, 1977-, et al.
(författare)
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Characterization of healthy skin using near infrared spectroscopy and skin impedance
- 2008
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Ingår i: Medical and Biological Engineering and Computing. - : Springer Science and Business Media LLC. - 0140-0118 .- 1741-0444. ; 46:10, s. 985-995
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Tidskriftsartikel (refereegranskat)abstract
- Near infrared spectroscopy (NIR) and skin impedance (IMP) spectroscopy are two methods suggested for diagnoses of diseases inducing adverse effects in skin. The reproducibility of these methods and their potential value in non-invasive diagnostics were investigated. Measurements were performed in vivo on healthy skin at five anatomic body sites on eight young women. partial least squares discriminant analysis showed that both methods were useful for classification of the skin characteristics at the sites. Inter-individually the NIR model gave 100% correct classification while the IMP model provided 92%. Intra-individually the NIR model gave 88% correct classification whereas the IMP model did not provide any useful classification. The correct classification was increased to 93% when both datasets were combined, which demonstrates the value of adding information. Partial least squares discriminant analysis gave 72% correct predictions of skin sites while the combined model slightly improved to 73%.
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| 8. |
- Bodén, Ida, 1977-, et al.
(författare)
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In vivo skin measurements with a novel probe head for simultaneous skin impedance and near-infrared spectroscopy
- 2011
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Ingår i: Skin research and technology. - : Wiley. - 0909-752X .- 1600-0846. ; 17:4, s. 494-504
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Tidskriftsartikel (refereegranskat)abstract
- Background/purpose: Near-infrared (NIR) spectroscopy and skin impedance (IMP) measurements are useful techniques for objective diagnostics of various skin diseases. Here, we present a combined probe head for simultaneous, time-saving NIR spectroscopy and skin impedance measurements. The probe also ensures that both measurements are performed under equal conditions and at the same skin location.Methods: Finite element method simulations were performed for evaluation of the impedance. In vivo skin measurements were performed and combined NIR and impedance spectra were analysed by means of multivariate methods with respect to body location, age and gender. The classification rate was determined by a planar discriminant analysis. Reproducibility was investigated by calculation of scatter values and statistical significance between overlapping groups was assessed by the calculation of intra-model distances, q.Results: The novel probe yielded rapid reproducible results and was easy to manage. Significant differences between skin locations and to a lesser extent age groups and gender were demonstrated.Conclusion: With the novel probe, statistically significant differences between overlapping classes in score plots can be confirmed by calculating intra-model distances. The influence of molecular differences in the skin at different body locations is larger than the influence of gender or age and therefore relevant reference measurements are discussed.
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| 9. |
- Bourdieu, Pierre, et al.
(författare)
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Leve idrottspedagogiken : En vänbok tillägnad Lars-Magnus Engström
- 2005
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Vem ägnar sig åt idrott? Vilken betydelse har fritiden i barns och ungdomars liv? Vad innebär hälsa i skolämnet idrott och hälsa?Leve idrottspedagogiken! tillägnas Lars-Magnus Engström. Texterna i boken speglar delar av det idrottspedagogiska forskningsområdet i Sverige, vars framväxt Lars-Magnus Engström varit den främste företrädaren för. Läsaren får här ta del av exempelvis idrottskulturen, fritidskulturen och skolans ämne idrott och hälsa. Genomgående handlar texterna om villkoren för barns och ungdomars deltagane och om de olika lärprocesser som sker i anslutning till idrottsutövning.Lars-Magnus Engström har gjort betydande insatser som forskare och lärare samt som professor vid Lärarhögskolan i Stockholm och vid Gymnastik- och idrottshögskolan. I snart fyrtion år har han arbetat med studier kring påverkans- och lärprocesser i idrott. Hans forskning har främst kretsat kring människors idrottsvanor och vilka som utvecklar en fysiskt aktiv livsstil. Idrotts- och motionsutövningar ger både ett så kallat egenvärde och investeringsvärde. Med dessa begrepp bland många andra har Lars-Magnus Engström bidragit till en fördjupad vetenskaplig förståelse av idrottskulturen.De flesta författarna har eller har haft Lars-Magnus Engström som handledare och tillhör forskningsgruppen för pedagogik, idrott och fritidskultur. Redaktörer för boken är Karin Redelius och Håkan Larsson.
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