| 1. |
- Karlsson, Håkan K R, et al.
(författare)
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Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise.
- 2004
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Ingår i: American Journal of Physiology. Endocrinology and Metabolism. - : American Physiological Society. - 0193-1849 .- 1522-1555. ; 287:1, s. E1-7
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to investigate the effect of resistance exercise alone or in combination with oral intake of branched-chain amino acids (BCAA) on phosphorylation of the 70-kDa S6 protein kinase (p70(S6k)) and mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK1/2), and p38 MAPK in skeletal muscle. Seven male subjects performed one session of quadriceps muscle resistance training (4 x 10 repetitions at 80% of one repetition maximum) on two occasions. In a randomized order, double-blind, crossover test, subjects ingested a solution of BCAA or placebo during and after exercise. Ingestion of BCAA increased plasma concentrations of isoleucine, leucine, and valine during exercise and throughout recovery after exercise (2 h postexercise), whereas no change was noted after the placebo trial. Resistance exercise led to a robust increase in p70(S6k) phosphorylation at Ser(424) and/or Thr(421), which persisted 1 and 2 h after exercise. BCAA ingestion further enhanced p70(S6k) phosphorylation 3.5-fold during recovery. p70(S6k) phosphorylation at Thr(389) was unaltered directly after resistance exercise. However, during recovery, Thr(389) phosphorylation was profoundly increased, but only during the BCAA trial. Furthermore, phosphorylation of the ribosomal protein S6 was also increased in the recovery period only during the BCAA trial. Exercise led to a marked increase in ERK1/2 and p38 MAPK phosphorylation, which was completely suppressed upon recovery and unaltered by BCAA. In conclusion, BCAA, ingested during and after resistance exercise, mediate signal transduction through p70(S6k) in skeletal muscle.
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| 2. |
- Alänge, Sverker, 1951, et al.
(författare)
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Ledarskap ur koncernchefsperspektiv
- 1998
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Många tecken tyder på att vi är mitt inne i ett paradigmskifte, där ett nytt sätt att bedriva verksamhet påverkar såväl tillverkande industri som privat och offentlig serviceverksamhet. Detta nya sätt att bedriva verksamhet karakteriseras av att samtliga människor inom en organisation engageras i att använda alla sina resurser, inklusive sin inneboende kreativitet, till att på bästa sätt tillgodose eller överträffa kunders förväntningar. Denna förändring ställer i sin tur nya krav på ledarstil, förankring av visioner och mål, motivationssystem, kontinuerligt lärande och processynsätt. Toppledarens betydelse för större förändringar i inriktning och grundläggande värderingar, dvs. ett paradigmskifte, har påpekats av många forskare och i litteraturen förekommer flera exempel på betydelsen av toppledares involvering och engagemang i större förändringsprocesser, både från Sverige och i internationella företag. Boken baseras på intervjuer med tolv koncernchefer vid några av Sveriges största företag: Astra, Electrolux, Posten, SAS, S-E Banken, SJ, Skandia, SKF, Stora, Telia, Tetra-Laval och Vattenfall. Boken presenterar och analyserar koncernchefernas samlade syn på ledarskap och krav på ledaregenskaper, idag och i framtiden. Boken innehåller även en jämförelse med andra ledares uppfattning om ledarskap. På frågor om morgondagens ledarskap; om vad koncerncheferna anser kommer att krävas av storföretagsledare i framtiden och om finns det behov av att förändra och utveckla dagens ledarskap kan svaren sammanfattas i fyra behov: Integritet, förmåga att få med sig sina medarbetare, mångkulturell kompetens samt förmåga att hantera ny teknologi och nya organisationsformer. Dessutom betonade några chefer vikten av att inse att framtidens krav är dagens verklighet, dvs. att framtiden redan är här.
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| 3. |
- Andersson, B, et al.
(författare)
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Ökad fysisk aktivitet viktigt för att bromsa sjukfrånvaron
- 2015
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Ingår i: Dagens nyheter, DN.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Försäkringskassans rapport (DN Debatt 27/11 2015) visar att sjukfrånvaron fortsätter att öka och lovar att kraftsamla i sjukförsäkringshandläggningen. Men, precis som Försäkringskassan skriver, kommer det inte att räcka för att nå regeringens mål. Regeringens åtgärdsprograms program i sju punkter för att minska sjukfrånvaron saknar en viktig komponent. Det måste kompletteras med fysisk aktivitet som ett åttonde område för att trenden ska kunna brytas, skriver 13 debattörer.
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| 4. |
- Andersson, Daniel, 1977, et al.
(författare)
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Supply Voltage Drop Study Considering On-Chip Self Inductance of a 32-bit Processor's Power Grid
- 2009
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Ingår i: 2009 IEEE Workshop on Signal Propagation on Interconnects, SPI '09; Strasbourg; France; 12 May 2009 through 15 May 2009. - 9781424444892
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Konferensbidrag (refereegranskat)abstract
- Conventional IR drop analysis suggests that on-chip inductive effects can be neglected when estimating supply voltage drops. We present a supply voltage drop analysis for a commercial 32-bit application processor. Our power grid model uses a backbone RL extracted netlist of the processor's power grid, complemented with capacitances from the processor design and a current signature defined by the worst-case switching test vector, located in the power-up sequence of the processor. Our circuit simulations show that on-chip self inductance makes the actual supply voltage drop deviate by more than 55% and 25% from the ∼6% and ∼8% drop, respectively, of nominal supply voltage that a conventional IR power grid model yields.
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| 5. |
- Andersson, Eva A, et al.
(författare)
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Abdominal and hip flexor muscle activation during various training exercises.
- 1997
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Ingår i: European Journal of Applied Physiology and Occupational Physiology. - : Springer Science and Business Media LLC. - 0301-5548 .- 1432-1025 .- 1439-6319 .- 1439-6327. ; 75:2, s. 115-23
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this study was to provide objective information on the involvement of different abdominal and hip flexor muscles during various types of common training exercises used in rehabilitation and sport. Six healthy male subjects performed altogether 38 different static and dynamic training exercises trunk and hip flexion sit-ups, with various combinations of leg position and support, and bi- and unilateral leg lifts. Myoelectric activity was recorded with surface electrodes from the rectus abdominis, obliquus externus, obliquus internus, rectus femoris, and sartorius muscles and with indwelling fine-wire electrodes from the iliacus muscle. The mean electromyogram amplitude, normalised to the highest observed value, was compared between static and dynamic exercises separately. The hip flexors were highly activated only in exercises involving hip flexion, either lifting the whole upper body or the legs. In contrast, the abdominal muscles showed marked activation both during trunk and hip flexion sit-ups. In hip flexion sit-ups, flexed and supported legs increased hip flexor activation, whereas such modifications did not generally alter the activation level of the abdominals. Bilateral, but not unilateral, leg lifts required activation of abdominal muscles. In trunk flexion sit-ups an increased activation of the abdominal muscles was observed with increased flexion angle, whereas the opposite was true for hip flexion sit-ups. Bilateral leg lifts resulted in higher activity levels than hip flexion sit-ups for the iliacus and sartorius muscles, while the opposite was true for rectus femoris muscles. These data could serve as a basis for improving the design and specificity of test and training exercises.
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| 6. |
- Andersson, Eva A, et al.
(författare)
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Intramuscular EMG from the hip flexor muscles during human locomotion.
- 1997
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Ingår i: Acta Physiologica Scandinavica. - 0001-6772 .- 1365-201X. ; 161:3, s. 361-70
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Tidskriftsartikel (refereegranskat)abstract
- The purpose was to investigate the activation pattern of five major hip flexor muscles and its adaptation to changing speed and mode of progression. A total of 11 healthy subjects performed walking and running on a motor-driven treadmill at speeds ranging from 1.0 to 6.0 m s-1. Intramuscular fine-wire electrodes were used to record myoelectric signals from the iliacus, psoas, sartorius, rectus femoris and tensor fascia latae muscles. The basic pattern, with respect to number of activation periods, remained the same irrespective of speed and mode of progression. However, differences in the relative duration and timing of onset of activation occurred between individual muscles. Over the speed range in walking, a progressively earlier onset was generally seen for the activation period related to hip flexion. Changes in EMG amplitude were measured in the iliacus and psoas muscles and showed a marked increase and difference between walking and running at speeds above 2.0 m s-1. Thus, the alternating flexion-extension movements at the hip during locomotion appear to be governed by a rather fixed 'neural program' which normally only needs minor modulations to accomplish the adjustments accompanying an increase in speed of progression as well as a change from walking to running.
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| 7. |
- Andersson, Eva A, 1958-, et al.
(författare)
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Maximal Aerobic Power versus Performance in Two Aerobic Endurance Tests among Young and Old Adults
- 2011
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Ingår i: Gerontology. - : S. Karger AG. - 0304-324X .- 1423-0003. ; :Aug, s. 1-11
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Tidskriftsartikel (refereegranskat)abstract
- Background: Aerobic fitness is of great value for reducing risk of mortality and cardiovascular diseases. Objective: This study evaluated the performance in and correlations between a new test (five-minute pyramid test, 5MPT), the six-minute walk-test (6MWT) and maximal oxygen uptake (VO(2max)) among old and young adults. Methods: Forty-four habitually active adults (females and males), 23 old (64-79 years) and 21 young (20-32 years) participated. In the 5MPT, the participants moved back and forth along a short walkway (5.5 m) over boxes (height: 'old people' 0.42 m, 'young people' 0.62 m) arranged like an elongated step pyramid for 5 min. Power in the pyramid test (5MPT(power)) was calculated as the product of numbers of laps, body weight, gravity and highest box level divided by time. A 6MWT and a maximal cycle ergometer test for direct measurements of VO(2max) were also performed. In all tests heart rate, with on-line electrocardiography, and perceived exertion were recorded. Results: There was a strong correlation between the 5MPT(power) and VO(2max) for the entire group studied (r = 0.98), and each of the four subgroups old and young females and males separately (r = 0.78-0.98). Contrary to several earlier studies, especially involving people with various diseases, the present data showed that 6MWT cannot be used to predict VO(2max) among old females and young adults. The correlation with VO(2max) was weaker for the 6MWT than for the 5MPT(power). The relative performance values for the old compared to the young (ratio old/young × 100) were considerably lower in 5MPT(power) and VO(2max) (47-55%) than in distance and 'work' in the 6MWT (82-86%). Conclusions: The results, with age and gender variations, can be valuable information in health-fitness contexts, since measuring physical aerobic capacity is very significant in connection with risk evaluations of mortality and various diseases. The 5MPT is a rapid, functional, easy and inexpensive tool for predicting assessed maximal aerobic power.
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| 8. |
- Andersson, Eva A., et al.
(författare)
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Physical activity for persons with obesity—a health project reported
- 2008
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Ingår i: Forum on Public Policy Online. - : Oxford Round Table. - 1938-9809. ; 4:Spring
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Tidskriftsartikel (refereegranskat)abstract
- In public health contexts, increased physical activity habits and fitness (aerobic and strength capacities) are positively related for promoting health and preventing and treating common diseases/problems, including obesity and overweight. A strongly graded inverse association between physical activity and obesity has been shown both for adults and children. However, a lower mortality risk has been shown for those with greater weight but good aerobic capacity than for those of recommended weight but less fit. On the basis of a health project with physical activity for persons with or without obesity, the paper discusses evidence-based methods for promoting physical activity. General guidelines for the amount of physical activity for persons are described, as are the numerous physiological and medical advantages of physical activity. The economic benefits are also illustrated. The paper exemplifies methods of measuring physical activity habits and physical fitness. These two factors must be observed when showing improvements in public-health contexts, including groups with obesity.
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| 9. |
- Andersson, Eva A., et al.
(författare)
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Äldre blir starkare av Hälsoprojektet
- 2013
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Ingår i: Svensk Idrottsforskning. - Stockholm : Centrum för idtrottsforskning (CIF). - 1103-4629. ; 22:1, s. 25-27
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- En god kondition och styrka har samband med förbättrad hälsa, minskad förekomst av flera folksjukdomar samt ökad livslängd. Fysiologiska tester kan vara stimulerande för äldre att följa utvecklingen av sin fysiska kapacitet och för olika aktörer som vill göra hälsoutvärderingar.
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| 10. |
- Andersson, Eva, et al.
(författare)
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Can a six-minute shuttle walk test predict maximal oxygen uptake?
- 2011
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Ingår i: Gazzetta Medica Italiana. - Torino : Minerva Medica. - 0393-3660 .- 1827-1812. ; 170:3, s. 163-70
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Tidskriftsartikel (refereegranskat)abstract
- Aim. This study evaluates the results of and correlations between the six-minute walk-test (6MWT) and a maximal oxygen uptake (VO2max) test among physically active young adults. Methods. Sixty-three adults (33 females and 30 males) aged 18-38 years participated. 6MWT and a maximal running treadmill test for measurements of VO2max were performed. 6MWT reliability was also evaluated. Results. Mean distance in the 6MWT for the females was 848 (685-976) m and for the males 866 (704-1077) m. The gender differences were considerably less for the 6MWT (2%) than in the VO2max test, both normalized to body weight (21%) and in absolute form (35%). The mean values, for the female and male subjects in the VO2max were 46.7 and 58.9 ml/kg/min and 2.94 and 4.53 l/min, respectively. The data showed a very low, not significant, correlation (r=-0.02-0.32) between walking distance in the 6MWT and VO2max. Conclusions: The 6MWT-distance for this physically active young adult group, which previously not has been studied, was considerably higher than in earlier reports for various other groups. In contrast to several prior studies, especially involving people with various diseases, the present data, on healthy active adults, showed that distance in the 6MWT cannot predict maximal oxygen uptake. The present results may be related to the low potential of walking as a locomotor form to tax the cardio-respiratory system sufficiently for this group. Since aerobic capacity is correlated with increased survival, these new data and given comparisons with previous reports are specially valuable when evaluating fitness in various sports and health contexts.
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