| 1. |
- Lagerqvist, Bo, et al.
(författare)
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Outcomes 1 year after thrombus aspiration for myocardial infarction.
- 2014
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Ingår i: New England Journal of Medicine. - : Massachusetts Medical Society. - 0028-4793 .- 1533-4406. ; 371:12, s. 1111-1120
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Tidskriftsartikel (refereegranskat)abstract
- Routine intracoronary thrombus aspiration before primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) has not been proved to reduce short-term mortality. We evaluated clinical outcomes at 1 year after thrombus aspiration.
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| 2. |
- Völz, Sebastian, 1980, et al.
(författare)
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Long-term mortality in patients with ischaemic heart failure revascularized with coronary artery bypass grafting or percutaneous coronary intervention : insights from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)
- 2021
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Ingår i: European Heart Journal. - : Oxford University Press. - 0195-668X .- 1522-9645. ; 42:27, s. 2657-2664
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: To compare coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for treatment of patients with heart failure due to ischaemic heart disease.METHODS AND RESULTS: We analysed all-cause mortality following CABG or PCI in patients with heart failure with reduced ejection fraction and multivessel disease (coronary artery stenosis >50% in ≥2 vessels or left main) who underwent coronary angiography between 2000 and 2018 in Sweden. We used a propensity score-adjusted logistic and Cox proportional-hazards regressions and instrumental variable model to adjust for known and unknown confounders. Multilevel modelling was used to adjust for the clustering of observations in a hierarchical database. In total, 2509 patients (82.9% men) were included; 35.8% had diabetes and 34.7% had a previous myocardial infarction. The mean age was 68.1 ± 9.4 years (47.8% were >70 years old), and 64.9% had three-vessel or left main disease. Primary designated therapy was PCI in 56.2% and CABG in 43.8%. Median follow-up time was 3.9 years (range 1 day to 10 years). There were 1010 deaths. Risk of death was lower after CABG than after PCI [odds ratio (OR) 0.62; 95% confidence interval (CI) 0.41-0.96; P = 0.031]. The risk of death increased linearly with quintiles of hospitals in which PCI was the preferred method for revascularization (OR 1.27, 95% CI 1.17-1.38, Ptrend < 0.001).CONCLUSION: In patients with ischaemic heart failure, long-term survival was greater after CABG than after PCI.
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| 3. |
- Dworeck, Christian, et al.
(författare)
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Radial artery access is associated with lower mortality in patients undergoing primary PCI : a report from the SWEDEHEART registry
- 2020
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Ingår i: European Heart Journal. - : Sage Publications. - 2048-8726 .- 2048-8734. ; 9:4, s. 323-332
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: The purpose of this observational study was to evaluate the effects of radial artery access versus femoral artery access on the risk of 30-day mortality, inhospital bleeding and cardiogenic shock in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.Methods: We used data from the SWEDEHEART registry and included all patients who were treated with primary percutaneous coronary intervention in Sweden between 2005 and 2016. We compared patients who had percutaneous coronary intervention by radial access versus femoral access with regard to the primary endpoint of all-cause death within 30 days, using a multilevel propensity score adjusted logistic regression which included hospital as a random effect.Results: During the study period, 44,804 patients underwent primary percutaneous coronary intervention of whom 24,299 (54.2%) had radial access and 20,505 (45.8%) femoral access. There were 2487 (5.5%) deaths within 30 days, of which 920 (3.8%) occurred in the radial access and 1567 (7.6%) in the femoral access group. After propensity score adjustment, radial access was associated with a lower risk of death (adjusted odds ratio (OR) 0.70, 95% confidence interval (CI) 0.55-0.88,P = 0.025). We found no interaction between access site and age, gender and cardiogenic shock regarding 30-day mortality. Radial access was also associated with a lower adjusted risk of bleeding (adjusted OR 0.45, 95% CI 0.25-0.79,P = 0.006) and cardiogenic shock (adjusted OR 0.41, 95% CI 0.24-0.73,P = 0.002).Conclusions: In patients with ST-elevation myocardial infarction, primary percutaneous coronary intervention by radial access rather than femoral access was associated with an adjusted lower risk of death, bleeding and cardiogenic shock. Our findings are consistent with, and add external validity to, recent randomised trials.
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| 4. |
- Nordenskjöld Syrous, Alma, 1979, et al.
(författare)
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Reasons for physician-related variability in end-of-life decision-making in intensive care
- 2021
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Ingår i: Acta Anaesthesiologica Scandinavica. - : Wiley. - 0001-5172 .- 1399-6576. ; 65:8, s. 1102-1108
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Tidskriftsartikel (refereegranskat)abstract
- Background There is increasing evidence that the individual physician is the main factor influencing variability in end-of-life decision-making in intensive care units. End-of-life decisions are complex and should be adapted to each patient. Physician-related variability is problematic as it may result in unequal assessments that affect patient outcomes. The primary aim of this study was to investigate factors contributing to physician-related variability in end-of-life decision-making. Method This is a qualitative substudy of a previously conducted study. In-depth thematic analysis of semistructured interviews with 19 critical care specialists from five different Swedish intensive care units was performed. Interviews took place between 1 February 2017 and 31 May 2017. Results Factors influencing physician-related variability consisted of different assessment of patient preferences, as well as intensivists' personality and values. Personality was expressed mainly through pace and determination in the decision-making process. Personal prejudices appeared in decisions, but few respondents had personally witnessed this. Avoidance of criticism and conflicts as well as individual strategies for emotional coping were other factors that influenced physician-related variability. Many respondents feared criticism for making their assessments, and the challenging nature of end-of-life decision-making lead to avoidance as well as emotional stress. Conclusion Variability in end-of-life decision-making is an important topic that needs further investigation. It is imperative that such variability be acknowledged and addressed in a more formal and transparent manner. The ethical issues faced by intensivists have recently been compounded by the devastating impact of the COVID-19 pandemic, demonstrating in profound terms the importance of the topic.
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| 5. |
- Odenstedt, Anders
(författare)
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Art and History in Gadamer's Hermeneutics
- 2007
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Ingår i: Phanomenologische Forschungen. - : Felix Meiner Verlag GmbH. - 0342-8117. ; 12, s. 75-93
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Tidskriftsartikel (refereegranskat)abstract
- This paper discusses Hans-Georg Gadamer’s account of what he sees as a major change in the approach to the Western philosophical and aesthetic traditions that began in the second half of the eighteenth century, and the results of this change today. According to Gadamer, these traditions ceased to be binding at this time and became objects of historical research. Instead of being seen even as potential sources of insight, traditional knowledge claims and works of art were subjected to historical and aesthetic analysis. Gadamer holds that these approaches have partially come to encompass the present as well. Thus, modern art has tended to sidestep cognitive and pedagogical tasks in, e.g., proceeding in a purely aesthetic, playful way. And the study of history has been seen as providing insight into the contextually determined nature of presuppositions, those of the modern age included. Gadamer argues that these perceptions of art and history unduly neglect their ability to provide learning.
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| 6. |
- Odenstedt, Anders
(författare)
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Art, History, and the Decline of Tradition
- 2017
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Ingår i: Gadamer on Tradition. - Cham : Springer International Publishing. - 9783319595566 - 9783319595580 ; , s. 33-62
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Bokkapitel (refereegranskat)abstract
- Gadamer argues, in a prescriptive way, that the rise of the historical sciences coincided with a regrettable decline in the authority of the Western philosophical, religious, and aesthetic traditions. But Gadamer also argues, in a more descriptive way, that the history of Western culture since Greek antiquity fundamentally involves a number of uninterrupted traditions, or even a single uninterrupted tradition. Gadamer’s account of modern aesthetics and art shows a similar ambiguity. Gadamer argues, in a prescriptive way, that modern aesthetics and art are regrettably plagued by an “aesthetic consciousness” (ästhetisches Bewußtsein) that reduces the creation and reception of art to mere aesthetic play and that breaks with tradition. But Gadamer also argues, in a more descriptive way, that, ultimately, even the most esoteric modern artists retain a dependence on tradition.
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| 7. |
- Odenstedt, Anders
(författare)
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Being a Child of One’s Time : Gadamer and Hegel on Thought and Historical Context
- 2017
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Ingår i: Gadamer on Tradition. - Cham : Springer International Publishing. - 9783319595566 - 9783319595580 ; , s. 191-216
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Bokkapitel (refereegranskat)abstract
- This chapter compares Hegel’s and Gadamer’s accounts of context-dependence. Hegel asserts that the individual is a “child of his time.” However, Hegel describes the relationship between thought and the historical context in different ways, and this chapter singles out four versions of the claim that the individual is a “child of his time” and of the historical context. Parallels to these claims can be found in Gadamer, and where such parallels are absent this can be explained by the difference between Hegel’s and Gadamer’s views of Bildung as third nature. Hegel is part of the reaction by the emerging science of history against the Enlightenment tendency to blame past historical epochs for contingently failing to live up to contemporary standards of rationality. Gadamer shares this reaction, although at the same time arguing that Hegel regrettably continues certain Enlightenment modes of thought.
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| 8. |
- Odenstedt, Anders
(författare)
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Being a Child of One’s Time : Hegel on Thought and Cultural Context
- 2012
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Ingår i: International philosophical quarterly. - : Philosophy Documentation Center. - 0019-0365 .- 2153-8077. ; 52:3, s. 267-284
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Tidskriftsartikel (refereegranskat)abstract
- Hegel often argues that the individual is fated to be a "child of his time" in the sense that the mind of the individual (“subjective Spirit”) is profoundly and inescapably influenced by its time, i.e. the cultural context which forms its temporal setting (“objective Spirit”). However, Hegel also suggests that the individual need not in every case be thus influenced after all. This paper discusses the following four main versions of Hegel's account of the relation between mind and its cultural context: (i) that everyday, "uneducated" (ungebildetes) thought harbors the presuppositions of its cultural context unreflectively; (ii) that philosophy overcomes the form of this unreflectiveness, but that the content of philosophy remains its time since it tries to reflectively justify current presuppositions; (iii) that this reflection occurs when a culture declines, and that philosophy, too, therefore is a child of its time, albeit in a different sense than everyday thought; and(iv) that an individual may be a minority thinker, despite what claim (i) says, but that even such an individual is a child of his time in the (even weaker) sense that he is unable to influence it, and that this is so precisely because he "transcends" it.
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| 9. |
- Odenstedt, Anders, 1965-
(författare)
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Cognition and cultural context : An inquiry into Gadamer's theory of context-dependence
- 2009
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- This study deals with the problem of the dependence of thought on its historical context, as discussed by the German philosopher Hans-Georg Gadamer (1900-2002).Gadamer argues that historical contexts are cognitively homogeneous in an unreflected way, and that this state of affairs typically involves basic presuppositions (Vorurteile) that underlie seemingly divergent views in such a context. However, in opposition to this claim, it may be argued that historical contexts contain a shared conceptual framework, or a preoccupation with certain problems, but that they may nevertheless be heterogeneous in terms of presuppositions as such. But Gadamer holds that the cognitive heterogeneity of a historical context is easily overrated by individuals situated in it insofar as shared presuppositions are not questioned or even detected.A central issue of this study is the extent to which unreflected context-dependence persists in the modern era. Gadamer, while not denying that the very notion of this dependence requires that it is at least partly reflected, argues that the scope of this reflection has been overestimated, notably by philosophers in the Enlightenment tradition. Gadamer refers to Karl Popper and Jürgen Habermas as examples of this overestimation. According to Gadamer, the current awareness of context-dependence and of, e.g., the corresponding problem of anachronism in historical study, surpasses that of previous epochs, but this difference is nevertheless a matter of degree rather than kind.In what sense is it correct to say that the very notion of unreflected context-dependence requires reflection, and that it therefore casts doubt on the claims made by Gadamer himself? According to a rather frequent objection to Gadamer, awareness of context-dependence occurs in a situation in which this dependence is reduced. Conversely, an individual subject to unreflected context-dependence would not be able to recognise his or her predicament in this respect. In this study, this objection is discussed in connection with general problems of interpretation in cultural and historical studies.
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| 10. |
- Odenstedt, Anders
(författare)
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Cognition and Cultural Context : An Inquiry into Gadamer's Theory of Context-Dependence
- 2001
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This study deals with the problem of the context-dependence of thought, as dealt with by the German philosopher Hans-Georg Gadamer (1900-2002). Gadamer stresses what he sees as the difficulty of bringing to awareness and criticising influences which preserve such dependence, and the role of traditions (Überlieferungen) in this regard. This study seeks to distinguish between different ways in which Gadamer's claims in this respect might be understood and to assess them.Gadamer affirms the cohesion of historical contexts, thereby arguing that it typically involves basic presuppositions (Vorurteile) that underlie seemingly divergent views in a way which is not reflected on by individuals sharing such a context. However, in opposition to this claim, it may be argued that contexts contain a shared conceptual framework, or a preoccupation with certain problems, but that they may nevertheless be heterogeneous in terms of presuppositions as such. But Gadamer holds that the cognitive heterogeneity of contexts is easily overrated insofar as common presuppositions are not questioned or even detected.A central issue of this study is the extent to which unreflected context-dependence persists in the modern era. Gadamer, while not denying that the very notion of context-dependence requires that it is at least partly reflected, argues that the scope of this reflection has been overestimated, notably by philosophers in the Enlightenment tradition; he refers to Karl Popper and Jürgen Habermas as examples of this overestimation. According to Gadamer, the current awareness of context-dependence and of, e.g., the corresponding problem of anachronism in historical study, surpasses that of previous epochs, but this difference is nevertheless a matter of degree rather than kind.In what sense is it correct to say that the very notion of unreflected context-dependence requires reflection, and that it therefore casts doubt on the claims made by Gadamer himself? According to a rather frequent objection to Gadamer, awareness of context-dependence occurs in a situation in which this dependence is reduced. Conversely, an individual subject to unreflected context-dependence would not be able to recognise his or her predicament in this respect. In this study, this objection is discussed in connection with general problems of interpretation in cultural and historical studies.
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