| 1. |
- Allanach, Benjamin C., et al.
(författare)
-
Simple and statistically sound strategies for analysing physical theories
- 2022
-
Ingår i: Reports on progress in physics (Print). - : Institute of Physics Publishing (IOPP). - 0034-4885 .- 1361-6633. ; 85:5
-
Forskningsöversikt (refereegranskat)abstract
- Physical theories that depend on many parameters or are tested against data from many different experiments pose unique challenges to statistical inference. Many models in particle physics, astrophysics and cosmology fall into one or both of these categories. These issues are often sidestepped with statistically unsound ad hoc methods, involving intersection of parameter intervals estimated by multiple experiments, and random or grid sampling of model parameters. Whilst these methods are easy to apply, they exhibit pathologies even in low-dimensional parameter spaces, and quickly become problematic to use and interpret in higher dimensions. In this article we give clear guidance for going beyond these procedures, suggesting where possible simple methods for performing statistically sound inference, and recommendations of readily-available software tools and standards that can assist in doing so. Our aim is to provide any physicists lacking comprehensive statistical training with recommendations for reaching correct scientific conclusions, with only a modest increase in analysis burden. Our examples can be reproduced with the code publicly available at Zenodo.
|
|
| 2. |
- Bousquet, J., et al.
(författare)
-
ARIA 2016 : Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle
- 2016
-
Ingår i: Clinical and Translational Allergy. - : Wiley. - 2045-7022. ; 6:1
-
Forskningsöversikt (refereegranskat)abstract
- The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA - disseminated and implemented in over 70 countries globally - is now focusing on the implementation of emerging technologies for individualized and predictive medicine. MASK [MACVIA (Contre les Maladies Chroniques pour un Vieillissement Actif)-ARIA Sentinel NetworK] uses mobile technology to develop care pathways for the management of rhinitis and asthma by a multi-disciplinary group and by patients themselves. An app (Android and iOS) is available in 20 countries and 15 languages. It uses a visual analogue scale to assess symptom control and work productivity as well as a clinical decision support system. It is associated with an inter-operable tablet for physicians and other health care professionals. The scaling up strategy uses the recommendations of the European Innovation Partnership on Active and Healthy Ageing. The aim of the novel ARIA approach is to provide an active and healthy life to rhinitis sufferers, whatever their age, sex or socio-economic status, in order to reduce health and social inequalities incurred by the disease.
|
|
| 3. |
- Ellis, John, et al.
(författare)
-
Neutrino fluxes from constrained minimal supersymmetric standard model lightest supersymmetric particle annihilations in the Sun
- 2010
-
Ingår i: Physical Review D. Particles and fields. - 0556-2821 .- 1089-4918. ; 81:8, s. 85004-
-
Tidskriftsartikel (refereegranskat)abstract
- We evaluate the neutrino fluxes to be expected from neutralino lightest supersymmetric particle (LSP) annihilations inside the Sun, within the minimal supersymmetric extension of the standard model with supersymmetry-breaking scalar and gaugino masses constrained to be universal at the grand unified theory scale [the constrained minimal supersymmetric standard model (CMSSM)]. We find that there are large regions of typical CMSSM (m(1/2), m(0)) planes where the LSP density inside the Sun is not in equilibrium, so that the annihilation rate may be far below the capture rate. We show that neutrino fluxes are dependent on the solar model at the 20% level, and adopt the AGSS09 model of Serenelli et al. for our detailed studies. We find that there are large regions of the CMSSM (m(1/2), m(0)) planes where the capture rate is not dominated by spin-dependent LSP-proton scattering, e. g., at large m(1/2) along the CMSSM coannihilation strip. We calculate neutrino fluxes above various threshold energies for points along the coannihilation/rapid-annihilation and focus-point strips where the CMSSM yields the correct cosmological relic density for tan beta = 10 and 55 for mu > 0, exploring their sensitivities to uncertainties in the spin-dependent and-independent scattering matrix elements. We also present detailed neutrino spectra for four benchmark models that illustrate generic possibilities within the CMSSM. Scanning the cosmologically favored parts of the parameter space of the CMSSM, we find that the IceCube/DeepCore detector can probe at best only parts of this parameter space, notably the focus-point region and possibly also at the low-mass tip of the coannihilation strip.
|
|
| 4. |
- Ellis, John, et al.
(författare)
-
Neutrino fluxes from nonuniversal Higgs mass LSP annihilations in the Sun
- 2011
-
Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 83:8, s. 085023-
-
Tidskriftsartikel (refereegranskat)abstract
- We extend our previous studies of the neutrino fluxes expected from neutralino LSP annihilations inside the Sun to include variants of the minimal supersymmetric extension of the Standard Model (MSSM) with squark, slepton and gaugino masses constrained to be universal at the GUT scale, but allowing one or two nonuniversal supersymmetry breaking parameters contributing to the Higgs masses (NUHM1,2). As in the constrained MSSM (CMSSM) with universal Higgs masses, there are large regions of the NUHM parameter space where the LSP density inside the Sun is not in equilibrium, so that the annihilation rate may be far below the capture rate, and there are also large regions where the capture rate is not dominated by spin-dependent LSP-proton scattering. The spectra possible in the NUHM are qualitatively similar to those in the CMSSM. We calculate neutrino-induced muon fluxes above a threshold energy of 10 GeV, appropriate for the IceCube/DeepCore detector, for points where the NUHM yields the correct cosmological relic density for representative choices of the NUHM parameters. We find that the IceCube/DeepCore detector can probe regions of the NUHM parameter space in addition to analogues of the focus point strip and the tip of the coannihilation strip familiar from the CMSSM. These include regions with enhanced Higgsino-gaugino mixing in the LSP composition, that occurs where neutralino mass eigen-states cross over. On the other hand, rapid-annihilation funnel regions in general yield neutrino fluxes that are unobservably small.
|
|
