| 1. |
- Björck, Niclas, et al.
(författare)
-
Djur och växter
- 2008
-
Ingår i: Mellan hav och skog.
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)
|
|
| 2. |
- Bäckström, Malin, 1967, et al.
(författare)
-
Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells.
- 2003
-
Ingår i: The Biochemical journal. - 1470-8728. ; 376:Pt 3, s. 677-86
-
Tidskriftsartikel (refereegranskat)abstract
- We have developed an expression system for the production of large quantities of recombinant MUC1 mucin in CHO-K1 (Chinese-hamster ovary K1) cells. The extracellular part of human MUC1, including 16 MUC1 tandem repeats, was produced as a fusion protein with murine IgG Fc, with an intervening enterokinase cleavage site for the removal of the Fc tail. Stable MUC1-IgG-producing CHO-K1 clones were generated and were found to secrete MUC1-IgG into the culture medium. After adaptation to suspension culture in protein-free medium in a bioreactor, the fusion protein was secreted in large quantities (100 mg/l per day) into the culture supernatant. From there, MUC1 could be purified to homogeneity using a two-step procedure including enterokinase cleavage and ion-exchange chromatography. Capillary liquid chromatography MS of released oligosaccharides from CHO-K1-produced MUC1 identified the main O-glycans as Galbeta1-3GalNAc (core 1) and mono- and di-sialylated core 1. The glycans occupied on average 4.3 of the five potential O-glycosylation sites in the tandem repeats, as determined by nano-liquid chromatography MS of partially deglycosylated Clostripain-digested protein. A very similar O-glycan profile and site occupancy was found in MUC1-IgG produced in the breast carcinoma cell line T47D, which has O-glycosylation typical for breast cancer. In contrast, MUC1-IgG produced in another breast cancer cell line, MCF-7, showed a more complex pattern with both core 1- and core 2-based O-glycans. This is the first reported production of large quantities of recombinant MUC1 with a breast cancer-like O-glycosylation that could be used for the immunotherapy of breast cancer.
|
|
| 3. |
- Claesson, A., et al.
(författare)
-
Diode-pumped miniature lasers using microstructured silicon carriers
- 2000
-
Ingår i: Electronics Letters. - : Institution of Engineering and Technology (IET). - 0013-5194 .- 1350-911X. ; 36:5, s. 433-434
-
Tidskriftsartikel (refereegranskat)abstract
- A new versatile design concept for compact diode-pumped solid-state lasers based on a microstructured silicon carrier with etched V-grooves is presented. The carrier provides efficient thermal management as well as compact integration and alignment of all active acid passive optical components. In initial experiments, an Nd:YAG laser delivered a continuous-wave output of 3W.
|
|
| 4. |
- Claesson, Åsa, et al.
(författare)
-
Novel design for diode-pumped miniature lasers using microstructured silicon carriers
- 2000
-
Ingår i: Advanced Solid State Lasers. - : Optica Publishing Group.
-
Konferensbidrag (refereegranskat)abstract
- A new design concept for compact diode-pumped solid-state lasers is presented. The design is based on a microstructured silicon carrier with etched v-grooves. This silicon microbench provides efficient thermal management at 10W pumping level, as well as compact integration and alignment of all active and passive optical components of compact diode-pumped solid-state lasers. In initial experiments, a Nd:YAG laser built on the microbench delivered a continuous-wave output of 3W.
|
|
| 5. |
- Dahlstedt, Magnus, 1975-, et al.
(författare)
-
Dissonant futures : occupational trajectories, gender and class in contemporary municipal adult education in Sweden
- 2018
-
Ingår i: Journal of Education and Work. - : Informa UK Limited. - 1363-9080 .- 1469-9435. ; 31:1, s. 16-27
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of this article is to problematize the ways class and gender are played out in adult students’ narratives about their occupational choice and future. Drawing on Beverly Skeggs, we analyse how students think about future occupations, what motivates them towards these and how they are able to form their future in relation to them. Taking on Sweden as a case, our results show that students’ narratives on their future occupations are classed as well as gendered. In their vision of future occupations, working-class students tend to focus on occupations helping and caring for others, while middle-class students tend to focus on work more as a means of fulfilling themselves as individuals. These differences are also gendered. Female students are more likely than their male counterparts to picture their future occupations in relation to having children and a family. This tells us that in the female students’ narratives, there tends to be a strong focus on caring – for their families as well as in future occupations.
|
|
| 6. |
- Dahlstedt, Magnus, et al.
(författare)
-
Formation of respectable citizens : precarious work and uncertain futures in a f-cked up world
- 2016
-
Konferensbidrag (refereegranskat)abstract
- Drawing on research on gender and class and especially on the work of Beverly Skeggs we analyse adult educational student’s stories of their future occupations and future lives. We argue that these narratives of the future are both gendered and class specific. The results shows that there are echoes from the past, where the working class focused on being diligent, caring, modest and respectable. There is also a gender difference among the working class students, where women picture their future occupations in relation to having children and a family. For the working class female students their future occupations are further often connected to working with people, i.e. as care workers, teachers or for instance physiotherapist – i.e. work that involve caring in one way or another. Different results are seen in the analysis of middle class students that are more likely to focus on their individual self-realisation, where the futures are grander and not so much connected to a specific time and space. Another important result is that the working class students are modest in the narratives of their future occupations. Imagined occupations would mean a certain amount of social mobility, but rather modest ones.
|
|
| 7. |
- Dahlstedt, Magnus, et al.
(författare)
-
Longing to belong : Stories of (non)belonging in multi-ethnic Sweden
- 2017
-
Ingår i: Nordic Journal of Migration Research. - : De Gruyter Open. - 1799-649X. ; 7:4, s. 197-204
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of this article is to contribute to an understanding of contemporary processes of negotiations concerning belonging and non-belonging to the Swedish social community. Taking on a theoretical approach on belonging inspired by Yuval-Davis and Jacobsen, the article analyses three individual stories of women who have migrated to Sweden. Out of this analysis, focusing on how these women claim their belonging to a Swedish social community at the same time as they in different ways are denied such belonging by others, we may conclude that although each of the stories told is unique and articulates an individual experience, there are striking similarities in how their claims of belonging, with its related implications for belonging, are not acknowledged by others. In a way, these individual stories tell us something about some of the crucial challenges regarding belonging in contemporary multi-ethnic Sweden, as well as Europe.
|
|
| 8. |
- Dahlstedt, Magnus, et al.
(författare)
-
Medborgarskapandets paradoxer : Medborgarskapspositioneringar i berättelser om tillhörighet i migrationens tid
- 2017
-
Ingår i: Sociologisk forskning. - : Sveriges Sociologförbund. - 0038-0342 .- 2002-066X. ; 54:1, s. 31-50
-
Tidskriftsartikel (refereegranskat)abstract
- Paradoxes of citizen formation: Citizenship positioning in stories about belonging in an era of migrationThis article analyzes the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies and stories of how they ended up in Sweden, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach. In all, the stories address the crucial question of who should be included into the social community and on what conditions – and who should be left out? This particular question is also at the very centre of the political debate in today’s Europe. On the one hand, there are strong arguments about the ’death of multiculturalism’ and demands for new forms of ethno-culturally graduated citizenship – also in Sweden. On the other hand, in Sweden as well as in other European countries, claims for the development of a new and more inclusive societal community have been raised, expanding the rights of citizens to accommodating also those who have been excluded from them.
|
|
| 9. |
- Dahlstedt, Magnus, et al.
(författare)
-
Medborgarskapandets paradoxer [Paradoxes of citizen formation] : Medborgarskapspositioneringar i berättelser om tillhörighet i migrationens tid. [Citizenship positioning in stories about belonging in an era of migration]
- 2017
-
Ingår i: Sociologisk forskning. - : Sveriges sociologförbund. - 0038-0342 .- 2002-066X. ; 54:1-2, s. 31-50
-
Tidskriftsartikel (refereegranskat)abstract
- This article analyzes the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies and stories of how they ended up in Sweden, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach. In all, the stories address the crucial question of who should be included into the social community and on what conditions – and who should be left out? This particular question is also at the very centre of the political debate in today’s Europe. On the one hand, there are strong arguments about the ’death of multiculturalism’ and demands for new forms of ethno-culturally graduated citizenship – also in Sweden. On the other hand, in Sweden as well as in other European countries, claims for the development of a new and more inclusive societal community have been raised, expanding the rights of citizens to accommodating also those who have been excluded from them.
|
|
| 10. |
- Dahlstedt, Magnus, et al.
(författare)
-
To belong or not to belong : negotiating citizenship in an age of migration
- 2016
-
Konferensbidrag (refereegranskat)abstract
- 2015. More than a million people are seeking refuge in Europe. Over water or over land, children as well as adults are fleeing from war, persecution and poverty. Thousands of them disappear without a trace or drown beneath the waves. Most of the refugees come from the war-torn Syria (International Organisation for Migration 2015). Throughout the member states of the European Union, exceptional policy measures are taken in order to handle the so-called ‘refugee crisis’ – intensified border control, the introduction of ID checks at specific checkpoints as well as within the borders of a country and restrictive rules for the reception of asylum seekers. This precarious situation in Europe addresses a number of crucial questions about the state of citizenship and belonging in contemporary Europe – in an age of large-scale international migration. In an era of international migration established conceptions of citizenship, of who the citizen is or should be, are challenged. International migration highlights some of the fundamental issues of citizenship: which characteristics, abilities or values should the citizen have and how are the relationships between the citizen and society arranged? In the context of international migration certain individuals are seen as ‘naturally’ belonging to the national community they inhabit, guaranteeing a set of rights, while others are seen as not belonging. The question, however, is: Who are included in the societal community, who are excluded, and what conditions are used to decide? This article analyses the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach.
|
|
