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Sökning: WFRF:(Olsrud J)

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  • Hansson, B., et al. (författare)
  • MR-safety in clinical practice at 7T: Evaluation of a multistep screening process in 1819 subjects
  • 2022
  • Ingår i: Radiography. - : Elsevier BV. - 1078-8174. ; 28:2, s. 454-459
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: MR facilities must implement and maintain adequate screening and safety procedures to ensure safety during MR examinations. The aim of this study was to evaluate a multi-step MR safety screening process used at a 7T facility regarding incidence of different types of safety risks detected during the safety procedure. Methods: Subjects scheduled for an MR examination and having entered the 7T facility during 2016–2019 underwent a pre-defined multi-step MR safety screening process. Screening documentation of 1819 included subjects was reviewed, and risks identified during the different screening steps were compiled. These data were also related to documented decisions made by a 7T MR safety committee and reported MR safety incidents. Results: Passive or active implants (n = 315) were identified in a screening form and/or an additional documented interview in 305 subjects. Additional information not previously self-reported by the subject, regarding implants necessitating safety decisions performed by the staff was revealed in the documented interview in 102 subjects (106 items). In total, the 7T MR safety committee documented a decision in 36 (2%) of the included subjects. All of these subjects were finally cleared for scanning. Conclusion: A multi-step screening process allows a thorough MR screening of subjects, avoiding safety incidents. Different steps in the process allow awareness to rise and items to be detected that were missed in earlier steps. Implications for practice: Safety questions posed at a single timepoint during an MR screening process might not reveal all safety risks. Repetition and rephrasing of screening questions leads to increased detection of safety risks. This could be effectively mitigated by a multi-step screening process. A multi-disciplinary safety committee is efficient at short notice responding to unexpected safety issues. © 2021 The Author(s)
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  • Ivarsson, K, et al. (författare)
  • Feedback interstitial diode laser (805 nm) thermotherapy system: Ex vivo evaluation and mathematical modeling with one and four-fibers
  • 1998
  • Ingår i: Lasers in Surgery and Medicine. - 0196-8092. ; 22:2, s. 86-96
  • Tidskriftsartikel (refereegranskat)abstract
    • Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in ground bovine muscle using either a single laser fiber or four-fibers. The target temperature at one (feedback) thermistor, placed 5 mm from one of the laser fibers, was set to 50 degrees C and was maintained by means of stepwise power regulation. The temperature distribution was monitored using multiple thermistor probes. A numerical model based on the bioheat equation was used to calculate the temperature distributions. Results: Temperature regulation was excellent with a tendency towards better regulation in the four-fiber than in the single-fiber experiments. Agreement between calculated and measured temperatures was good. The coagulated (>55 degrees C) and hyperthermic (>45 degrees C) volumes were 6 and 10-11 times larger, respectively, with four-fibers than with a single fiber. Conclusion: It is concluded that the stepwise power regulation system was efficient in maintaining a stable target temperature. The results indicate that the system can produce lesion volumes adequate for treating a relatively large tumor in a single session and that computer simulation may be useful for predicting temperature distribution. (C) 1998 Wiley-Liss, Inc.
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  • Olsrud, Maria, et al. (författare)
  • Response of ericoid mycorrhizal colonization and functioning to global change factors
  • 2004
  • Ingår i: New Phytologist. - : Wiley. - 1469-8137 .- 0028-646X. ; 162:2, s. 459-469
  • Tidskriftsartikel (refereegranskat)abstract
    • Here, we investigated effects of increased atmospheric CO2 concentration, increased temperatures, and both factors in combination on ericoid mycorrhizal colonization, mycorrhizal functioning and below-ground carbon allocation in a subarctic forest understorey, to evaluate the hypothesis that photosynthesis is a primary driver for mycorrhizal colonization. Treatment effects on ecosystem processes were investigated using C-14-pulse labelling and photosynthesis measurements in combination with analysis of ergosterol content in roots. The effects on delta(15)N in leaves were also studied. Ergosterol content in hair roots was positively correlated with ecosystem photosynthesis and was higher in heat- and CO2-treated plots. Leaves from CO2 Plots tended to be more depleted in N-15 compared with controls both for Vaccinium myrtillus and V. vitis-idaea. Our results suggest that changes in ecosystem photosynthesis, plant carbon (C) Allocation may give rise to changing mycorrhizal colonization under elevated CO2 and temperature. The role of mycorrhizas in ecosystem N-cycling may change on a long-term basis as inorganic N availability declines with increasing levels of atmospheric CO2.
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