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1.	Nascimento, MM, et al. (author) Effect of hepatitis C serology on C-reactive protein in a cohort of Brazilian hemodialysis patients 2005 In: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. - 0100-879X. ; 38:5, s. 783-788 Journal article (peer-reviewed)
2.	Nascimento, MM, et al. (author) The influence of hepatitis C and iron replacement therapy on plasma pentosidine levels in haemodialysis patients 2004 In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 0931-0509. ; 19:12, s. 3112-3116 Journal article (peer-reviewed)
3.	Nascimento, MM, et al. (author) The prognostic impact of fluctuating levels of C-reactive protein in Brazilian haemodialysis patients: a prospective study 2004 In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 0931-0509. ; 19:11, s. 2803-2809 Journal article (peer-reviewed)
4.	Pachaly, MA, et al. (author) Interleukin-6 is a better predictor of mortality as compared to C-reactive protein, homocysteine, pentosidine and advanced oxidation protein products in hemodialysis patients 2008 In: Blood purification. - : S. Karger AG. - 1421-9735 .- 0253-5068. ; 26:2, s. 204-210 Journal article (peer-reviewed)abstract Inflammatory markers predict mortality in hemodialysis (HD) patients, whereas a possible association between oxidative stress (OS) markers and survival is less clear. We assessed the impact on all-cause mortality of baseline inflammatory [high-sensitivity C-reactive protein and interleukin-6 (IL-6)] and OS markers (advanced oxidation protein products, pentosidine, homocysteine) in 112 HD patients. We found no significant correlations between inflammatory and OS markers. During the 5.5 years of follow-up, 51 patients died. In a Kaplan-Meier analysis, the survival rate was reduced in patients with IL-6 higher than the median (IL-6 >4.2 pg/ml) (log- rank = 6.47; p = 0.01), in diabetics (log-rank = 12.26; p = 0.0005) and in older patients (log-rank = 11.22; p = 0.0008). Moreover, in Cox analysis only IL-6 and age were independently associated with mortality. We conclude that in this group of prevalent Brazilian HD patients, IL-6 was a better predictor of survival than other inflammatory and OS markers.

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Stenvinkel, P (4); Lindholm, B (4); Riella, MC (4); Hayashi, SY (4); Manfro, RC (4); Pachaly, MA (4); show more...; Suliman, ME (3); Renner, L (3); Nascimento, MM (3); Qureshi, AR (2); Bruchfeld, A (2); Pecoits-Filho, R (2); Pecoits, R (1); do Nascimento, MM (1); show less...

University: Karolinska Institutet (4)

Language: English (4)

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