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- Niemi, MEK, et al.
(författare)
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- 2021
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swepub:Mat__t
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- Lee, J. -H, et al.
(författare)
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Comparative study on added resistance of a bulk carrier in regular head and oblique waves
- 2020
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Ingår i: Proceedings of the International Offshore and Polar Engineering Conference. - : International Society of Offshore and Polar Engineers. - 9781880653845 ; , s. 3385-3393
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Konferensbidrag (refereegranskat)abstract
- In this study, a comparative study on motion response and added resistance of a Supramax bulk carrier (K-Supramax Original) in regular waves was carried out to evaluate the reliabilities and accuracies of experimental and numerical simulation techniques. Two kinds of experiments were performed; one is the towing tank model testing for head wave conditions conducted at Seoul National University, and the other is the free-running model test for head and oblique wave conditions conducted at SSPA Sweden AB. Also, nine numerical computation results submitted by seven institutions were compared with the experimental data. The computation results were obtained by various seakeeping analysis methods such as the 2D strip theory, 3D Rankine panel method, and Computational Fluid Dynamics (CFD) based analysis. Based on the comparison, the characteristics of each numerical technique and resultant accuracies of seakeeping analyses were investigated. It was also confirmed that different results were obtained although the same program was used because of the user dependencies; setting for computation parameters, numerical schemes, and mesh generations, etc. Furthermore, the sensitivities of seakeeping quantities with respect to wave amplitudes were examined by conducting both model tests and nonlinear numerical simulations for different wave slopes. Lastly, the tendencies of ship motion and added resistance depending on the heading angle were identified, and the reliabilities of experiments and numerical computations for oblique waves were discussed.
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| 10. |
- Legrain, Pierre, et al.
(författare)
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The Human Proteome Project : Current State and Future Direction
- 2011
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Ingår i: Molecular & Cellular Proteomics. - 1535-9476 .- 1535-9484. ; 10:7
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Tidskriftsartikel (refereegranskat)abstract
- After the successful completion of the Human Genome Project, the Human Proteome Organization has recently officially launched a global Human Proteome Project (HPP), which is designed to map the entire human protein set. Given the lack of protein-level evidence for about 30% of the estimated 20,300 protein-coding genes, a systematic global effort will be necessary to achieve this goal with respect to protein abundance, distribution, subcellular localization, interaction with other biomolecules, and functions at specific time points. As a general experimental strategy, HPP research groups will use the three working pillars for HPP: mass spectrometry, antibody capture, and bioinformatics tools and knowledge bases. The HPP participants will take advantage of the output and cross-analyses from the ongoing Human Proteome Organization initiatives and a chromosome-centric protein mapping strategy, termed C-HPP, with which many national teams are currently engaged. In addition, numerous biologically driven and disease-oriented projects will be stimulated and facilitated by the HPP. Timely planning with proper governance of HPP will deliver a protein parts list, reagents, and tools for protein studies and analyses, and a stronger basis for personalized medicine. The Human Proteome Organization urges each national research funding agency and the scientific community at large to identify their preferred pathways to participate in aspects of this highly promising project in a HPP consortium of funders and investigators.
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