| 1. |
- Moberg, Christina, et al.
(författare)
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De unga gör helt rätt när de stämmer staten
- 2022
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Ingår i: Aftonbladet. - 1103-9000.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
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| 2. |
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| 3. |
- Andersson, Magnus, et al.
(författare)
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Fiskbestånd och miljö i hav och sötvatten : Resurs- och miljööversikt 2012
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Detta är den nionde utgåvan av den samlade översikten över fisk- och kräftdjursbeståndens status i våra vatten. Kunskap om fiskbestånden och miljön är en förutsättning för att utnyttjandet av fiskresurserna skall bli bärkraftigt. För svenska vattenområden beskrivs miljöutvecklingen i ett ekosystemsperspektiv, dels för att tydliggöra fiskens ekologiska roll och beskriva yttre miljöfaktorer som påverkar fiskbestånden, dels för att belysa fiskets effekter på miljön.Fiskbestånd och miljö i hav och sötvatten är utarbetad av Sveriges lantbruksuniversitet (SLU), Institutionen för akvatiska resurser (SLU Aqua), på uppdrag av Havs- och vattenmyndigheten. Rapporten sammanfattar utveckling och beståndsstatus för de kommersiellt viktigaste fisk- och kräftdjursarterna i våra vatten. Bedömningar och förvaltningsråd är baserade på Internationella Havsforskningsrådets (ICES) rådgivning, SLU Aquas nationella och regionala provfiskedata, samt yrkesfiskets rapportering.
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| 4. |
- Börjesson Rivera, Miriam, 1978-
(författare)
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Practice makes perfect? : Sustainable practices with ICT and daily travel
- 2015
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The thesis shows how practice theory can be applied in different ways when exploring how daily life can be supported to become more environmentally sustainable. Ultimately the thesis aims to contribute to new knowledge on how to design policies and interventions that aim at facilitating environmentally sustainable practices. This thesis argues that practice theory is useful in the field of sustainability research since it offers as point of departure a perspective on human everyday life which decentres focus from individual behaviour and instead looks at how social practices are constructed by integrating and combining material, bodily and mental elements.The thesis discusses the following questions: i) How can the role of ICT in everyday life be conceptualized from a practice perspective?, ii) How can practice theory be used in order to describe and assess second order environmental effects? and iii) What are the key considerations from a practice perspective when designing social/physical interventions for sustainable mobility?The papers in this thesis all use practice theory as point of departure but with different outcomes. Practice theory is thus used conceptually, methodologically and analytically. The main conclusions of the thesis are: Changes in practices due to ICT usage will inevitably have environmental impacts, both negative and positive, and for policy-makers it is imperative to take this into consideration when planning for the future and actively support and facilitate sustainable social practices. Looking at changes in practices due to new ICT usage can be one way to include second order effects in environmental assessments, in this way contributing to a discussion of potential environmental impacts from implementing a new product, application or service.Interventions, such as a cargo bike pool or restrictive work travel policies, have the potential to change existing practices. However, the potential of these changes, depend on a variety of different factors which are more or less difficult to influence for the individual practitioner such as work location, time schedules, availability of transportation means and modes. Further, it is difficult to foresee exactly how such changes will look and if they sustain in the long run. Finally, it is not necessarily so that an intervention will have the desired outcome that was intended, the outcome might be something else, consequently this means that interventions need to be analysed and assessed from other perspectives, one being a practice perspective.
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| 5. |
- Carlström, Mattias, et al.
(författare)
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Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals
- 2008
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Ingår i: American Journal of Physiology - Renal Physiology. - : American Physiological Society. - 0363-6127 .- 1522-1466 .- 1931-857X. ; 294:2, s. 362-370
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Tidskriftsartikel (refereegranskat)abstract
- Hydronephrotic animals develop renal injury and hypertension, which is associated with an abnormal tubuloglomerular feedback (TGF). The TGF sensitivity is coupled to nitric oxide (NO) in the macula densa. The involvement of reduced NO availability in the development of hypertension in hydronephrosis was investigated. Hydronephrosis was induced by ureteral obstruction in young rats. Blood pressure and renal excretion were measured in adulthood, under different sodium conditions, and before and after chronic administration of either N-G- nitro-L-arginine methyl ester (L-NAME) or L-arginine. Blood samples for ADMA, SDMA, and L-arginine analysis were taken and the renal tissue was used for histology and determination of NO synthase (NOS) proteins. TGF characteristics were determined by stop-flow pressure technique before and after administration of 7-nitroindazole (7-NI) or L-arginine. Hydronephrotic animals developed salt-sensitive hypertension, which was associated with pressure natriuresis and diuresis. The blood pressure response to L-NAME was attenuated and L-arginine supplementation decreased blood pressure in hydronephrotic animals, but not in the controls. Under control conditions, reactivity and sensitivity of the TGF response were greater in the hydronephrotic group. 7-NI administration increased TGF reactivity and sensitivity in control animals, whereas, in hydronephrotic animals, neuronal NOS (nNOS) inhibition had no effect. L-Arginine attenuated TGF response more in hydronephrotic kidneys than in controls. The hydronephrotic animals displayed various degrees of histopathological changes. ADMA and SDMA levels were higher and the renal expressions of nNOS and endothelial NOS proteins were lower in animals with hydronephrosis. Reduced NO availability in the diseased kidney in hydronephrosis, and subsequent resetting of the TGF mechanism, plays an important role in the development of hypertension.
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| 6. |
- Cesta, Carolyn E, et al.
(författare)
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Polycystic ovary syndrome and psychiatric disorders: Co-morbidity and heritability in a nationwide Swedish cohort.
- 2016
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Ingår i: Psychoneuroendocrinology. - : Elsevier BV. - 1873-3360 .- 0306-4530. ; 73, s. 196-203
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Tidskriftsartikel (refereegranskat)abstract
- Polycystic ovary syndrome (PCOS) is an endocrine disorder affecting 5-15% of reproductive-aged women and characterized by high levels of circulating androgens. Given that androgens have been implicated in the aetiology of several psychiatric disorders, it was hypothesized that women with PCOS have high risk for psychiatric comorbidity. We aimed to investigate this risk amongst women with PCOS, as well as in their siblings, to elucidate if familial factors underlie any potential associations. Using the Swedish national registers, we identified all women diagnosed with PCOS between 1990 and 2013 (n=24,385), their full-siblings (n=25,921), plus matched individuals (1:10/100) from the general population and their full-siblings. Psychiatric disorder diagnoses were identified including schizophrenia, bipolar disorder, depressive and anxiety disorders, eating disorders, personality and gender identity disorder, autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD), tics, attempted and completed suicide. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using conditional logistic regression and adjusted ORs (AOR) were determined by adjustment for comorbid psychiatric disorders. Overall, women with PCOS had an increased odds of having at least one psychiatric disorder (OR=1.56 [95CI%, 1.51-1.61]). Crude ORs showed associations with nearly all psychiatric disorders included in this study. Following adjustment for comorbid psychiatric disorders, women with PCOS were still at a significantly increased risk for bulimia, schizophrenia, bipolar disorder, depressive and anxiety disorders, personality disorders, with the highest AORs for ASD (AOR=1.55 [95%CI, 1.32-1.81]) and tics (AOR=1.65 [95%CI, 1.10-2.47]). Significantly higher AORs were found for ASD in both brothers and sisters of women with PCOS, and for depressive, anxiety, and schizophrenia spectrum disorders in the sisters only. Notably, the crude ORs for attempted suicide were 40% higher in women with PCOS and 16% higher in their unaffected sisters. However, the AORs were greatly attenuated indicating that underlying psychiatric comorbidity is important for this association. Women with PCOS had higher risks for a range of psychiatric disorders not shown before. Elevated risk in their siblings suggests shared familial factors between PCOS and psychiatric disorders. This study is an important first step towards identifying the underlying mechanisms for risk of psychiatric disorders in women with PCOS. Health professionals treating women with PCOS should be aware that these patients - as well as their family members - are important targets for mental health care.
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| 7. |
- Chakarova, Roumiana, et al.
(författare)
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Superficial dose distribution in breast for tangential radiation treatment, Monte Carlo evaluation of Eclipse algorithms in case of phantom and patient geometries.
- 2011
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Ingår i: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. - : Elsevier BV. - 1879-0887.
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: The aim of this study is to examine experimentally and by the Monte Carlo method the accuracy of the Eclipse Pencil Beam Convolution (PBC) and Analytical Anisotropic Algorithm (AAA) algorithms in the superficial region (0-2cm) of the breast for tangential photon beams in a phantom case as well as in a number of patient geometries. The aim is also to identify differences in how the patient computer tomography data are handled by the treatment planning system and in the Monte Carlo simulations in order to reduce influences of these effects on the evaluation. MATERIALS AND METHODS: Measurements by thermoluminescent dosimeters and gafchromic film are performed for six MV tangential irradiation of the cylindrical solid water phantom. Tangential treatment of seven patients is investigated considering open beams. Dose distributions are obtained by the Eclipse PBC and AAA algorithms. Monte Carlo calculations are carried out by BEAMnrc/DOSXYZnrc code package. Calculations are performed with a calculation grid of 1.25×1.25×5mm(3) for PBC and 2×2×5mm(3) for AAA and Monte Carlo, respectively. Dose comparison is performed in both dose and spatial domains by the normalized dose difference method. RESULTS: Experimental profiles from the surface toward the geometrical center of the cylindrical phantom are obtained at the beam entrance and exit as well as laterally. Full dose is received beyond 2mm in the lateral superficial region and beyond 7mm at the beam entrance. Good agreement between experimental, Monte Carlo and AAA data is obtained, whereas PBC is seen to underestimate the entrance dose the first 3-4mm and the lateral dose by more than 5% up to 8mm depth. In the patient cases considered, AAA and Monte Carlo show agreement within 3% dose and 4mm spatial tolerance. PBC systematically underestimates the dose at the breast apex. The dimensions of region out of tolerance vary with the local breast shape. Different interpretations of patient boundaries in Monte Carlo and the Eclipse are found to influence the evaluation. Computer tomography marker wire may introduce local disturbance effects on the comparison as well. These factors are not related to the accuracy of the calculation algorithms and their effect is taken into account in the evaluation. CONCLUSIONS: The accuracy of AAA in the case of the solid water phantom is comparable with that of the Monte Carlo method. The AAA-Monte Carlo differences in the patient cases considered are within 3%, 4mm tolerance. The PBC algorithm does not give equivalent results. In the phantom case, PBC underestimates the lateral dose by more than 5% up to 8mm depth. The PBC-Monte Carlo differences in the patient cases are outside the tolerance at the breast apex. The dimension of region varies with the breast shape being typically 8-10mm long and 6-8mm deep.
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| 8. |
- Dawkins, Elena, 1984-
(författare)
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Sustainable consumption for policymakers: measuring, learning and acting
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Current patterns and levels of consumption are a key driver of unsustainable resource use and pollution, which contributes to global environmental degradation. Rapid reductions in environmental pressures are required to avoid irreversible loss of fragile ecosystems and social and economic crises. Consumption must become sustainable. Governments have an essential role to play in delivering this. The aim of this thesis is to examine three aspects of the policymaking process on sustainable consumption – measuring, learning and acting – and the links between them. Each aspect has a linked objective.Measuring: Assess existing and novel techniques for calculating the environmental pressures of consumption that enable government to measure and monitor a country’s progress towards sustainable consumptionLearning: Determine whether – and, if so, how – consumption-based indicators might better support policymaker learning on sustainable consumptionActing: Identify ways in which governments can enhance their actions to support sustainable consumptionThe research is presented in six papers and organised in three parts: one for each objective. Parts 1 and 2 investigate current and future opportunities for policymakers to measure the environmental pressures linked to their country’s consumption, what these mean for achieving sustainable consumption and whether consumption-based indicators support learning about sustainable consumption. These parts are based on the Swedish experience of sustainable consumption. Part 3 examines various sustainable consumption interventions and what these could mean for government action in the future. This part draws on examples from several countries. Qualitative and quantitative methods are used to answer these questions. These comprise systematic review and mapping, macro-environment economic modelling and analysis, interviews, workshops and focus groups.The results provide a number of insights. First, novel consumption-based measurements for Sweden highlight the scale of the challenge involved in achieving sustainable consumption and the importance of increasing the policy applicability of indicators. Second, while indicators provide some learning for policymakers, their contribution to changing existing practices and navigating political or institutional barriers is limited. The learning potential of indicators is constrained by institutional environments. Instead, learning must be structured and enabled by institutions. Third, with regard to the actions studied, increased government involvement appears a necessary and, to some actors, desirable option. Nonetheless, a number of barriers to and enabling factors for policy action to promote sustainable consumption must be considered. In terms of the connections between the three elements of measuring, learning and acting, what might first appear to be a linear relationship is in reality far more complex. Measurement does not necessarily lead to learning – and learning is not always followed by action. Policymakers act without the level of knowledge they would like while indicators remain unused and, in some cases, are even rejected. Learning comes from practitioners’ involvement in action, as well as research into the actions themselves, the problem and solutions. Understanding government efforts on measuring, learning and action to promote sustainable consumption offers insights into how these multiple factors might contribute, separately and together, to more sustainable consumption.
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| 9. |
- Höjer, Mattias, 1966-, et al.
(författare)
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Scenarios in selected tools for environmental systems analysis
- 2008
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Ingår i: Journal of Cleaner Production. - : Elsevier BV. - 0959-6526 .- 1879-1786. ; 16:18, s. 1958-1970
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Tidskriftsartikel (refereegranskat)abstract
- A number of different tools for analysing environmental impacts of different systems have been developed. These include procedural tools such as strategic environmental assessment (SEA) and environmental management systems (EMS) as well as analytical ones such as life cycle assessment (LCA), life cycle costing (LCC), cost-benefit analysis (CBA) and the system of economic and environmental accounts (SEEA) including input-output analysis (IOA). Descriptions or scenarios of the future are typically relevant elements in these tools, since they are often used to describe impacts in the future. For futures studies a number of different approaches and techniques have been developed. In an earlier paper we have presented a typology of different types of scenarios that respond to different types of questions. These include predictive scenarios, explorative scenarios and normative scenarios. The aim of this paper is to explore connections between selected tools for environmental systems analysis and different scenario types. Although there is a clear need for futures studies in several tools for environmental systems analysis, it is interesting to note that the literature on methodologies for and case studies of combinations of futures studies and environmental systems analysis tools is rather limited. This suggests that there is a need for further research in this area including both methodoloy and practical case studies.
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| 10. |
- Liu, Xiaodong, et al.
(författare)
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A 65 nm CMOS Wideband Radio Receiver with ΔΣ-Based A/D-Converting Channel-Select Filters
- 2016
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Ingår i: IEEE Journal of Solid-State Circuits. - 0018-9200. ; 51:7, s. 1566-1578
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents a wideband quadrature radio receiver employing ΔΣ-based A/D-converting channel-select filters (ADCSFs). The output of the quadrature passive mixer is directly connected to the input of the ADCSFs, where a first-order ΔΣ modulator is incorporated into a fourth-order Butterworth channel-select filter (CSF) to provide sufficient dynamic range for a cellular system. A design methodology for the ADCSF is derived, where the transfer function of the CSF is preserved. The 65 nm CMOS receiver has a frequency range of 0.6-3.0 GHz and can be programmed to support the 2xLTE20, LTE20, and LTE10 bandwidths. The receiver noise figure varies from 2.3 to 3.9 dB, with a current consumption in 2xLTE20 mode between 33 mA at 0.6 GHz and 44 mA at 3.0 GHz from a 1.2 V supply, including 10-21 mA for LO phase generation and distribution. The SNDR is 47-51 dB at an LO frequency of 1.8 GHz.
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