| 1. |
- Christodoulou, C., et al.
(författare)
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Seasonality of violent suicides in the Athens greater area
- 2009
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Ingår i: Journal of Suicide and Life-threatening Behaviour. - : Wiley. - 0363-0234 .- 1943-278X. ; 39:3, s. 321-331
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to ascertain suicide seasonality in the Greek population and to associate this seasonal variation with age, sex, and suicide method. Studying seasonality can be of help in establishing a public health policy, related with suicide prevention. This is an epidemiologic study based on forensic evidence. We studied the deaths caused by self-injury (trauma), namely deaths by violent suicide (not self-poisoning). Statistically significant suicide seasonality was established with a peak in May. This seasonal variation is attributed mainly to males. As for the method, suicide by hanging peaks in June and by shooting in April. It was also observed that seasonality for individuals above the age of 45 peaks in early May.
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| 2. |
- Beckman, Ulrika, et al.
(författare)
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Årsrapport : Könsdysforiregistret 2021
- 2022
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Rapport (populärvet., debatt m.m.)abstract
- Könsdysforiregistret (KDR) är ett nationellt kvalitetsregister med syfte att följa upp och utveckla den könsbekräftande vården i Sverige. Könsbekräftande vård är vård och behandling vid könsdysfori: ett psykiskt lidande eller en försämrad förmåga att fungera i vardagen som orsakas av att det vid födelsen tillskrivna könet inte stämmer överens med könsidentiteten. Vård vid könsdysfori tillhör såväl specialistpsykiatrin som varierande somatiska vårdområden.Registret ämnar följa personer livslångt och är unikt i sitt slag i världen. Flera specialiteter är involverade under utredning och behandling. Dessa är psykiatri, endokrinologi, plastikkirurgi, gynekologi, reproduktionsmedicin, logopedi, foniatri och dermatologi. Den könsbekräftande vården i landet är för närvarande centrerad till Lund, Göteborg/Alingsås, Linköping, Stockholm, Uppsala och Umeå samt till några andra orter. Vården följer de nationella kunskapsstöd som Socialstyrelsen har tagit fram (Socialstyrelsen 2015/2021).Vården vid könsdysfori är multidisciplinär och multiprofessionell. Ett nationellt kvalitetsregister behöver därför spegla hela vårdområdet och KDR avser att samla data från samtliga delar. Det innebär att uppgifter registreras av vuxenpsykiatrin och barn- och ungdomspsykiatrin, barnendokrinologi och vuxenendokrinologi, logopedi och plastikkirurgi. Registret skiljer sig från övriga nationella kvalitetsregister som vanligen samlar in uppgifter från en specialitet eller möjligen två. Vi har också ambitionen att följa patienter som påbörjat kontakten med barn- och ungdomspsykiatri och barnendokrinologi i registret för att erhålla långtidsinformation om denna grupp. KDR är anslutet till Registercentrum Syd i Lund sedan 2015 och IT-plattformen är 3C.Data började registreras i KDR 2017 och hade år 2021 17 registrerande enheter (av 35 möjliga). Det är ett 100-tal enskilda användare som är verksamma inom psykiatri, endokrinologi, logopedi och plastikkirurgi. Totalt deltar 1994 patienter i registret, varav 266 nya registreringar gjordes under 2021. Täckningsgraden varierar påtagligt mellan olika enheter i landet. Under 2021 och var det i medeltal 21 procent av psykiatrins nybesök som registrerades och drygt 40 procent av logopedins. Den totala täckningsgraden av patienter i landet uppskattas till 32 procent för registret i sin helhet 2021. Merparten av deltagarna i registret är mellan 18 och 25 år. I åldern 0–17 år var två tredjedelar tillskrivet kvinnligt kön vid födelsen. I äldre åldersgrupper var fördelningen utifrån tillskrivet kön vid födelsen jämnare.Före könsbekräftande behandling krävs utredning vid någon av landets sex utredningsenheter för könsdysfori. Det är stor skillnad på varifrån remisserna för utredning av könsdysfori kommer. När 7 möjligheten till egenremiss tydligt uttrycks är det 40–50 procent som väljer att skriva en egenremiss. Av samtliga deltagare hade 79,7 procent efter utredningen fått diagnosen F64.0 (Transsexualism), 6,6 procent F64.9 (Könsidentitetsstörning, ospecificerad) och 8,5 procent F64.8 (Andra specificerade könsidentitetsstörningar).En central kvalitetsindikator är väntetider. Sammanfattningsvis har väntetiderna till nybesök ökat kraftigt inom psykiatrins utredningsenheter, från i medeltal 9 månader föregående år till 17 månader 2021. De totala antalet faktiskt genomförda nybesök vid landets två största utredningsenheter har samtidigt minskat, och en enhet pausade utredningsverksamheten helt. Det är sammantaget en mycket oroväckande utveckling i den del av vårdkedjan som tar emot flest remisser per år.Inom endokrinologin gjordes mycket få nyregistreringar under året, men underlaget tyder på att vårdgarantin om 90 dagar hålls vid två enheter, medan väntetiden är 10 månader vid en tredje enhet. Logopedin har i medeltal 5 månaders väntetid, vilket är en förbättring gentemot tidigare år. Plastikkirurgin har nyss börjat registrera vid en enhet, denna enhet hade i medel 3,5 månads väntetid till sina nybesök.Eftersom endast delar av landets enheter registrerar och täckningsgraden är låg ger inte den data som presenterats i rapporten någon fullständig bild av den könsbekräftande vården i Sverige och informationen behöver tolkas med försiktighet. Eftersom vården utvecklas och kunskapsläget förändras snabbt har KDR behövt revideras flera gånger sedan starten. Information om utredning och behandling av barn och ungdomar har tillkommit, vilket krävt revidering av formulären framför allt inom psykiatri och endokrinologi under år 2020 och 2021. Detta har försenat enheter att komma i gång med registrering av data.Vi ser nu att registreringsgraden ökar 2022 i och med att viktiga uppdateringar är gjorda och nya formulär kan tas i bruk. De nya formulären innebär både förenklingar i inmatning av data och förbättrad datakvalitet. För mer aktuell data om väntetider och registrering hänvisas till hemsidan och Delårsrapport 2022-09-15. Denna årsrapport ska läsas med Årsrapport 2018 som bakgrund vad gäller den könsbekräftande vårdens historia i Sverige samt en mera utförlig kunskapssammanställning inklusive referenser. Det har ännu inte skett någon forskning på data från Könsdysforiregistret, vilket gör att inga egna artiklar kan presenteras. Mer information finns på registrets hemsida, www.konsdysforiregistret.se
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| 3. |
- Bedard, Annabelle, et al.
(författare)
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Mobile technology offers novel insights into the control and treatment of allergic rhinitis : The MASK study
- 2019
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Ingår i: Journal of Allergy and Clinical Immunology. - : MOSBY-ELSEVIER. - 0091-6749 .- 1097-6825. ; 144:1, s. 135-143
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Tidskriftsartikel (refereegranskat)abstract
- Background: Mobile health can be used to generate innovative insights into optimizing treatment to improve allergic rhinitis (AR) control. Objectives: A cross-sectional real-world observational study was undertaken in 22 countries to complement a pilot study and provide novel information on medication use, disease control, and work productivity in the everyday life of patients with AR. Methods: A mobile phone app (Allergy Diary, which is freely available on Google Play and Apple stores) was used to collect the data of daily visual analogue scale (VAS) scores for (1) overall allergic symptoms; (2) nasal, ocular, and asthma symptoms; (3) work; and (4) medication use by using a treatment scroll list including all allergy medications (prescribed and over-the-counter) customized for 22 countries. The 4 most common intranasal medications containing intranasal corticosteroids and 8 oral H-1-antihistamines were studied. Results: Nine thousand one hundred twenty-two users filled in 112,054 days of VASs in 2016 and 2017. Assessment of days was informative. Control of days with rhinitis differed between no (best control), single (good control for intranasal corticosteroid-treated days), or multiple (worst control) treatments. Users with the worst control increased the range of treatments being used. The same trend was found for asthma, eye symptoms, and work productivity. Differences between oral H-1-antihistamines were found. Conclusions: This study confirms the usefulness of the Allergy Diary in accessing and assessing behavior in patients with AR. This observational study using a very simple assessment tool (VAS) on a mobile phone had the potential to answer questions previously thought infeasible.
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| 4. |
- Bousquet, Jean, et al.
(författare)
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ARIA digital anamorphosis : Digital transformation of health and care in airway diseases from research to practice
- 2021
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Ingår i: Allergy. European Journal of Allergy and Clinical Immunology. - : John Wiley & Sons. - 0105-4538 .- 1398-9995. ; 76:1, s. 168-190
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Forskningsöversikt (refereegranskat)abstract
- Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
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| 5. |
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| 6. |
- Bränn, Emma, et al.
(författare)
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Longitudinal assessment of inflammatory markers in the peripartum period by depressive symptom trajectory groups
- 2022
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Ingår i: Brain, Behavior, & Immunity - Health. - : Elsevier. - 2666-3546. ; 22
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveMechanisms driving temporal fluctuations of inflammatory markers during pregnancy, and how these might differ between distinct perinatal depressive trajectories, are not well understood. The aim of this study was to investigate cytokines levels over the course of pregnancy in women with different trajectories of depressive symptoms peripartum, and relate the levels to levels of non-pregnant controls.MethodsBased on the Edinburgh Postnatal Depression Scale and/or selective serotonin reuptake inhibitors use, 131 women were categorized into: no (n = 65); antepartum (APD, n = 19), postpartum (PPD, n = 17) and persistent (n = 30) depressive symptoms. Plasma samples (n = 386) were analyzed for levels of interleukin (IL)-8, IL-18, Tumor necrosis factor-α, macrophage colony-stimulating factor (M-CSF), vascular endothelial growth factor A (VEGF-A) and fractalkine, at four different time-points (twice during pregnancy, during childbirth, and postpartum) using Bio-Plex Pro Human Cytokine Assays. Generalized linear mixed models were applied to analyze the associations between cytokine levels, time-point, perinatal depressive symptom trajectory group and their interaction.ResultsFor all markers but VEGF-A, pregnancy was associated with higher cytokine levels compared to the non-pregnant controls, with delivery being the most prominent time-point. For M-CSF, IL-18 and VEGF-A, levels were back to the non-pregnant status at postpartum week 8. An effect of perinatal depressive symptom trajectory groups on cytokine levels was found for VEGF-A. Women with PPD and women with APD had lower levels of VEGF-A throughout the study period compared to women with persistent depression, and women with PPD had lower levels compared to non-depressed women.ConclusionsLower levels of VEGF-A were noted among women in some trajectories of depressive symptoms peripartum. The peripartum period is a time of tremendous immune system adaptations. Standardization of time-points for cytokine measurements in studies of perinatal depression are important in order to draw valid conclusions on the role of the immune system in perinatal depression.
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| 7. |
- Christodoulou, C., et al.
(författare)
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Suicide and seasonality
- 2012
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Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 125:2, s. 127-146
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Seasonal variation of deaths by suicide offers an important pathway in the study of possible suicide determinants of suicide and consequently suicide prevention. Method: We conducted a review of the literature on suicide seasonality, assessing articles published between 1979 and 2009. Results: Themajority of the studies confirm a peak in spring, mainly for men, older individuals, and violent methods of suicide. A secondary peak during autumn is observed. There is no common seasonality pattern for suicide methods. However, there are also certain studies that did not confirm seasonal variation. Inconsistent results with reduced, unchanged, and even increased suicide seasonality have been reported. Aspects on the association between seasonality and suicides are discussed. Except sex, age, and method of suicide, other parameters were taken into account to find more specific characteristics of seasonality in suicides as well. The influence of clinical, bioclimatic, sociodemographic as well as biological factors seems to affect the seasonal variation. Conclusion: Studies from both the Northern and the Southern hemisphere report a seasonal pattern for suicides. These studies are not only an important source of epidemiological data for suicides but also represent a global effort to uncover hidden parameters of this selfdestructive behaviour.
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| 8. |
- Fransson, Emma, PhD, 1973-, et al.
(författare)
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Differentiated mental health patterns in pregnancy during COVID-19 first two waves in Sweden : a mixed methods study using digital phenotyping
- 2022
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 12:1
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Tidskriftsartikel (refereegranskat)abstract
- To utilize modern tools to assess depressive and anxiety symptoms, wellbeing and life conditions in pregnant women during the first two waves of the COVID-19 pandemic in Sweden. Pregnant women (n = 1577) were recruited through the mobile application Mom2B. Symptoms of depression, anxiety and wellbeing were assessed during January 2020–February 2021. Movement data was collected using the phone’s sensor. Data on Google search volumes for “Corona” and Covid-related deaths were obtained. Qualitative analysis of free text responses regarding maternity care was performed. Two peaks were seen for depressive symptoms, corresponding to the two waves. Higher prevalence of anxiety was only noted during the first wave. A moderating effect of the two waves in the association of depression, anxiety, and well-being with Covid deaths was noted; positive associations during the first wave and attenuated or became negative during the second wave. Throughout, women reported on cancelled healthcare appointments and worry about partners not being allowed in hospital. The association of mental health outcomes with relevant covariates may vary during the different phases in a pandemic, possibly due to adaptation strategies on a personal and societal/healthcare level. Digital phenotyping can help healthcare providers and governmental bodies to in real time monitor high-risk groups during crises, and to adjust the support offered.
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| 9. |
- Hall, Lynne, et al.
(författare)
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Map reading with an empathic robot tutor
- 2016
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Ingår i: ACMIEEE International Conference on Human-Robot Interaction. - Piscataway, NJ : IEEE. - 2167-2121. - 9781467383707
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Konferensbidrag (refereegranskat)
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| 10. |
- Iliadis, Stavros I, 1983-, et al.
(författare)
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Personality and risk for postpartum depressive symptoms
- 2015
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Ingår i: Archives of Women's Mental Health. - : Springer Science and Business Media LLC. - 1434-1816 .- 1435-1102. ; 18:3, s. 539-546
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Tidskriftsartikel (refereegranskat)abstract
- Postpartum depression (PPD) is a common childbirth complication, affecting 10-15 % of newly delivered mothers. This study aims to assess the association between personality factors and PPD. All pregnant women during the period September 2009 to September 2010, undergoing a routine ultrasound at Uppsala University Hospital, were invited to participate in the BASIC study, a prospective study designed to investigate maternal well-being. Depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) while the Depression Self-Rating Scale (DSRS) was used as a diagnostic tool for major depression. Personality traits were evaluated using the Swedish Universities Scale of Personality (SSP). One thousand thirty-seven non-depressed pregnant women were included in the study. Non-depressed women reporting high levels of neuroticism in late pregnancy were at high risk of developing postpartum depressive symptoms (PPDSs) at 6 weeks and 6 months after delivery, even after adjustment for confounders (adjusted odds ratio (aOR) = 3.4, 95 % confidence interval (CI) 1.8-6.5 and adjusted odds ratio (aOR) = 3.9, 95 % CI 1.9-7.9). The same was true for a DSRS-based diagnosis of major depression at 6 months postpartum. Somatic trait anxiety and psychic trait anxiety were associated with increased risk for PPDS at 6 weeks (aOR = 2.1, 95 % CI 1.2-3.5 and aOR = 1.9, 95 % CI 1.1-3.1), while high scores of mistrust were associated with a twofold increased risk for PPDS at 6 months postpartum (aOR 1.9, 95 % CI 1.1-3.4). Non-depressed pregnant women with high neuroticism scores have an almost fourfold increased risk to develop depressive symptoms postpartum, and the association remains robust even after controlling for most known confounders. Clinically, this could be of importance for health care professionals working with pregnant and newly delivered women.
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