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- Adiels, L., et al.
(författare)
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Investigations on baryonium and other rare pmacrp annihilation modes using high resolution pi0 spectrometers (PS 182)
- 1985
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Ingår i: Antiproton 1984. Proceedings of the VII European Symposium on Antiproton Interactions. - : Institution of Electrical Engineers (IEE). ; , s. 297-304
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Konferensbidrag (refereegranskat)abstract
- In the search for heavy, narrow exotic states such as baryonium or glueballs, carried out so far, various methods of high- and low-energy production, low-energy formation, and e+e- reactions were used. In particular, a search for baryonium states below threshold (mxlsimmppmacr) has shown some evidence [Richter et al., 1983, Brando et al., 1984] for a few states. However, the results of these measurements suffer from poor statistics. Among the possible methods which can be applied in the baryonium bound state research at LEAR, the authors consider the study of the reaction ppmacrrarrX+pi0 as the most promising. They have performed an experiment to study this reaction by means of an experimental set-up especially tailored for measuring monoenergetic pi0,s, allowing for both angular distribution measurements and high-resolution spectroscopy. They report on the preliminary results from our actual measurements of the inclusive pi0 and eta spectra following the antiproton annihilation at rest.
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| 2. |
- Adiels, Lars, et al.
(författare)
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A π0 and η spectrometer of lead glass and BGO for momenta up to 1 GeV/c
- 1986
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 244:3, s. 380-390
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Tidskriftsartikel (refereegranskat)abstract
- A spectrometer consisting of two sets of bismuth germanium oxide (BGO) crystals and a lead-glass array has been used to measure the [pi]0 and [eta] momentum spectra produced from proton-antiproton annihilations at rest. We describe the test of the BGO sets in electron beams of energies from 50 to 450 MeV. We discuss the method of construction and calibration of the lead-glass array, as well as procedures to extract the energy and position resolutions for detected photons. A momentum resolution ([sigma]) for [pi]0’s and [eta]’s of 4% and 3%, respectively has been achieved at momenta below 1 GeV/c.
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| 3. |
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| 4. |
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| 5. |
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| 6. |
- Adiels, L, et al.
(författare)
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Some results of experiment PS182 at LEAR
- 1986
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Ingår i: Antiproton 86. - Singspore : World Scientific Publishing. - 9971503131 ; , s. 199-204, s. 199-204
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 8. |
- Mccafferty, Kieran, et al.
(författare)
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HEROIC: a 5-year observational cohort study aimed at identifying novel factors that drive diabetic kidney disease: rationale and study protocol
- 2020
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Ingår i: BMJ Open. - : BMJ. - 2044-6055 .- 2044-6055. ; 10:9, s. e033923-
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Tidskriftsartikel (refereegranskat)abstract
- Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. INTRODUCTION: Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease worldwide and a major cause of premature mortality in diabetes mellitus (DM). While improvements in care have reduced the incidence of kidney disease among those with DM, the increasing prevalence of DM means that the number of patients worldwide with DKD is increasing. Improved understanding of the biology of DKD and identification of novel therapeutic targets may lead to new treatments. A major challenge to progress has been the heterogeneity of the DKD phenotype and renal progression. To investigate the heterogeneity of DKD we have set up The East and North London Diabetes Cohort (HEROIC) Study, a secondary care-based, multiethnic observational study of patients with biopsy-proven DKD. Our primary objective is to identify histological features of DKD associated with kidney endpoints in a cohort of patients diagnosed with type 1 and type 2 DM, proteinuria and kidney impairment. METHODS AND ANALYSIS: HEROIC is a longitudinal observational study that aims to recruit 500 patients with DKD at high-risk of renal and cardiovascular events. Demographic, clinical and laboratory data will be collected and assessed annually for 5 years. Renal biopsy tissue will be collected and archived at recruitment. Blood and urine samples will be collected at baseline and during annual follow-up visits. Measured glomerular filtration rate (GFR), echocardiography, retinal optical coherence tomography angiography and kidney and cardiac MRI will be performed at baseline and twice more during follow-up. The study is 90% powered to detect an association between key histological and imaging parameters and a composite of death, renal replacement therapy or a 30% decline in estimated GFR. ETHICS AND DISSEMINATION: Ethical approval has been obtained from the Bloomsbury Research Ethics Committee (REC 18-LO-1921). Any patient identifiable data will be stored on a password-protected National Health Services N3 network with full audit trail. Anonymised imaging data will be stored in a ISO27001-certificated data warehouse.Results will be reported through peer-reviewed manuscripts and conferences and disseminated to participants, patients and the public using web-based and social media engagement tools as well as through public events.
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