| 1. |
- Mulder, Renée L., et al.
(författare)
-
Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer : recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group
- 2021
-
Ingår i: The Lancet Oncology. - 1470-2045 .- 1474-5488. ; 22:2, s. 68-80
-
Forskningsöversikt (refereegranskat)abstract
- Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the literature and developed a clinical practice guideline that provides recommendations for ongoing communication methods for fertility preservation for patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger and their families. Moreover, the guideline panel formulated considerations of the ethical implications that are associated with these procedures. Grading of Recommendations Assessment, Development and Evaluation methodology was used to grade the evidence and recommendations. In this clinical practice guideline, existing evidence and international expertise are combined to develop transparent recommendations that are easy to use to facilitate ongoing communication between health-care providers and patients with childhood, adolescent, and young adult cancer who might be at high risk for fertility impairment and their families.
|
|
| 2. |
- Peate, I U, et al.
(författare)
-
Volcanic stratigraphy of large-volume silicic pyroclastic eruptions during Oligocene Afro-Arabian flood volcanism in Yemen
- 2005
-
Ingår i: Bulletin of Volcanology. - : Springer Science and Business Media LLC. - 0258-8900 .- 1432-0819. ; 68:2, s. 135-156
-
Tidskriftsartikel (refereegranskat)abstract
- A new stratigraphy for bimodal Oligocene flood volcanism that forms the volcanic plateau of northern Yemen is presented based on detailed field observations, petrography and geochemical correlations. The > 1 km thick volcanic pile is divided into three phases of volcanism: a main basaltic stage ( 31 to 29.7 Ma), a main silicic stage ( 29.7 to 29.5 Ma), and a stage of upper bimodal volcanism ( 29.5 to 27.7 Ma). Eight large-volume silicic pyroclastic eruptive units are traceable throughout northern Yemen, and some units can be correlated with silicic eruptive units in the Ethiopian Traps and to tephra layers in the Indian Ocean. The silicic units comprise pyroclastic density current and fall deposits and a caldera-collapse breccia, and they display textures that unequivocally identify them as primary pyroclastic deposits: basal vitrophyres, eutaxitic fabrics, glass shards, vitroclastic ash matrices and accretionary lapilli. Individual pyroclastic eruptions have preserved on-land volumes of up to similar to 850 km(3). The largest units have associated co-ignimbrite plume ash fall deposits with dispersal areas > 1 x 10(7) km(2) and estimated maximum total volumes of up to 5,000 km(3), which provide accurate and precisely dated marker horizons that can be used to link litho-, bio- and magnetostratigraphy studies. There is a marked change in eruption style of silicic units with time, from initial large-volume explosive pyroclastic eruptions producing ignimbrites and near-globally distributed tuffs, to smaller volume (< 50 km(3)) mixed effusive-explosive eruptions emplacing silicic lavas intercalated with tuffs and ignimbrites. Although eruption volumes decrease by an order of magnitude from the first stage to the last, eruption intervals within each phase remain broadly similar. These changes may reflect the initiation of continental rifting and the transition from pre-break-up thick, stable crust supporting large-volume magma chambers, to syn-rift actively thinning crust hosting small-volume magma chambers.
|
|
