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Träfflista för sökning "WFRF:(Pedersen Torben Professor) "

Sökning: WFRF:(Pedersen Torben Professor)

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1.
  • Gidofalvi, Gyözö, 1975- (författare)
  • Spatio-Temporal Data Mining for Location-Based Services
  • 2008
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Largely driven by advances in communication and information technology, such as the increasing availability and accuracy of GPS technology and the miniaturization of wireless communication devices, Location–Based Services (LBS) are continuously gaining popularity. Innovative LBSes integrate knowledge about the users into the service. Such knowledge can be derived by analyzing the location data of users. Such data contain two unique dimensions, space and time, which need to be analyzed. The objectives of this thesis are three–fold. First, to extend popular data mining methods to the spatio–temporal domain. Second, to demonstrate the usefulness of the extended methods and the derived knowledge in two promising LBS examples. Finally, to eliminate privacy concerns in connection with spatio–temporal data mining by devising systems for privacy–preserving location data collection and mining.   To this extent, Chapter 2 presents a general methodology, pivoting, to extend a popular data mining method, namely rule mining, to the spatio–temporal domain. By considering the characteristics of a number of real–world data sources, Chapter 2 also derives a taxonomy of spatio–temporal data, and demonstrates the usefulness of the rules that the extended spatio–temporal rule mining method can discover. In Chapter 4 the proposed spatio–temporal extension is applied to find long, sharable patterns in trajectories of moving objects. Empirical evaluations show that the extended method and its variants, using high–level SQL implementations, are effective tools for analyzing trajectories of moving objects. Real–world trajectory data about a large population of objects moving over extended periods within a limited geographical space is difficult to obtain. To aid the development in spatio–temporal data management and data mining, Chapter 3 develops a Spatio–Temporal ACTivity Simulator (ST–ACTS). ST–ACTS uses a number of real–world geo–statistical data sources and intuitive principles to effectively generate realistic spatio–temporal activities of mobile users.   Chapter 5 proposes an LBS in the transportation domain, namely cab–sharing. To deliver an effective service, a unique spatio–temporal grouping algorithm is presented and implemented as a sequence of SQL statements. Chapter 6 identifies ascalability bottleneck in the grouping algorithm. To eliminate the bottleneck, the chapter expresses the grouping algorithm as a continuous stream query in a data stream management system, and then devises simple but effective spatio–temporal partitioning methods for streams to parallelize the computation. Experimental results show that parallelization through adaptive partitioning methods leads to speed–ups of orders of magnitude without significantly effecting the quality of the grouping. Spatio–temporal stream partitioning is expected to be an effective method to scale computation–intensive spatial queries and spatial analysis methods for streams.   Location–Based Advertising (LBA), the delivery of relevant commercial information to mobile consumers, is considered to be one of the most promising business opportunities amongst LBSes. To this extent, Chapter 7 describes an LBA framework and an LBA database that can be used for the management of mobile ads. Using a simulated but realistic mobile consumer population and a set of mobile ads, the LBA database is used to estimate the capacity of the mobile advertising channel. The estimates show that the channel capacity is extremely large, which is evidence for a strong business case, but it also necessitates adequate user controls.   When data about users is collected and analyzed, privacy naturally becomes a concern. To eliminate the concerns, Chapter 8 first presents a grid–based framework in which location data is anonymized through spatio–temporal generalization, and then proposes a system for collecting and mining anonymous location data. Experimental results show that the privacy–preserving data mining component discovers patterns that, while probabilistic, are accurate enough to be useful for many LBSes.   To eliminate any uncertainty in the mining results, Chapter 9 proposes a system for collecting exact trajectories of moving objects in a privacy–preserving manner. In the proposed system there are no trusted components and anonymization is performed by the clients in a P2P network via data cloaking and data swapping. Realistic simulations show that under reasonable conditions and privacy/anonymity settings the proposed system is effective.
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2.
  • Holmström, Christine, 1969- (författare)
  • In Search of MNC Competitive Advantage : The Role of Foreign Subsidiaries as Creators and Disseminators of Knowledge
  • 2004
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Research on the multinational corporation (MNC) has highlighted the development of knowledge that occurs in geographically dispersed subsidiaries, and several scholars have emphasized the significance of subsidiary knowledge for the success of the MNC. This thesis contributes to the understanding of how knowledge is developed within MNC subsidiaries and how the development of subsidiary knowledge is related to the transfer of subsidiary knowledge and subsidiary impact on the performance of the larger MNC.The empirical setting consists of a combination of quantitative and qualitative data. The results of the empirical studies suggest that the development of subsidiary knowledge is contingent upon the business conditions within the local environment and, in particularly, interactive learning within relationships with important business actors external to the organization. Furthermore, the findings show that the development of knowledge within these subsidiaries is driven not only by external actors, but also by business relationships within the corporation. The results reveal that, whether a subsidiary learns and develops knowledge from external or internal sources has direct implications on how the knowledge can be used and applied by other units within the MNC, which in turn affects the extent to which the subsidiary can contribute to the performance of the MNC. It is also revealed that the barriers to transfer are especially manifest in situations in which a subsidiary is deeply embedded in relationships with demanding customers or suppliers. Thus, the embeddedness of subsidiaries in external relationships is a constraining factor for knowledge transfer. In situations in which the subsidiary is deeply embedded in its local market, the headquarters can influence the transfer across subsidiaries through the use of means such as centres of excellence.
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3.
  • Surendran, Praveen, et al. (författare)
  • Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
  • 2020
  • Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 52:12, s. 1314-1332
  • Tidskriftsartikel (refereegranskat)abstract
    • Genetic studies of blood pressure (BP) to date have mainly analyzed common variants (minor allele frequency > 0.05). In a meta-analysis of up to similar to 1.3 million participants, we discovered 106 new BP-associated genomic regions and 87 rare (minor allele frequency <= 0.01) variant BP associations (P < 5 x 10(-8)), of which 32 were in new BP-associated loci and 55 were independent BP-associated single-nucleotide variants within known BP-associated regions. Average effects of rare variants (44% coding) were similar to 8 times larger than common variant effects and indicate potential candidate causal genes at new and known loci (for example, GATA5 and PLCB3). BP-associated variants (including rare and common) were enriched in regions of active chromatin in fetal tissues, potentially linking fetal development with BP regulation in later life. Multivariable Mendelian randomization suggested possible inverse effects of elevated systolic and diastolic BP on large artery stroke. Our study demonstrates the utility of rare-variant analyses for identifying candidate genes and the results highlight potential therapeutic targets.
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