| 1. |
- Ferrando, Carlos, et al.
(författare)
-
Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy : a randomised controlled trial
- 2020
-
Ingår i: British Journal of Anaesthesia. - : ELSEVIER SCI LTD. - 0007-0912 .- 1471-6771. ; 124:1, s. 110-120
-
Tidskriftsartikel (refereegranskat)abstract
- Background: We aimed to examine whether using a high fraction of inspired oxygen (FIO2) in the context of an individualised intra- and postoperative open-lung ventilation approach could decrease surgical site infection (SSI) in patients scheduled for abdominal surgery. Methods: We performed a multicentre, randomised controlled clinical trial in a network of 21 university hospitals from June 6, 2017 to July 19, 2018. Patients undergoing abdominal surgery were randomly assigned to receive a high (0.80) or conventional (0.3) FIO2 during the intraoperative period and during the first 3 postoperative hours. All patients were mechanically ventilated with an open-lung strategy, which included recruitment manoeuvres and individualised positive end-expiratory pressure for the best respiratory-system compliance, and individualised continuous postoperative airway pressure for adequate peripheral oxyhaemoglobin saturation. The primary outcome was the prevalence of SSI within the first 7 postoperative days. The secondary outcomes were composites of systemic complications, length of intensive care and hospital stay, and 6-month mortality. Results: We enrolled 740 subjects: 371 in the high FIO2 group and 369 in the low FIO2 group. Data from 717 subjects were available for final analysis. The rate of SSI during the first postoperative week did not differ between high (8.9%) and low (9.4%) FIO2 groups (relative risk [RR]: 0.94; 95% confidence interval [CI]: 0.59-1.50; P=0.90]). Secondary outcomes, such as atelectasis (7.7% vs 9.8%; RR: 0.77; 95% CI: 0.48-1.25; P=0.38) and myocardial ischaemia (0.6% [n=2] vs 0% [n=0]; P=0.47) did not differ between groups. Conclusions: An oxygenation strategy using high FIO2 compared with conventional FIO2 did not reduce postoperative SSIs in abdominal surgery. No differences in secondary outcomes or adverse events were found.
|
|
| 2. |
- Piscicchia, Kristian, et al.
(författare)
-
First simultaneous K-p→Σ€0π0, Λπ0 cross section measurements at 98 MeV/c
- 2023
-
Ingår i: Physical Review C. - : American Physical Society (APS). - 2469-9985 .- 2469-9993. ; 108:5
-
Tidskriftsartikel (refereegranskat)abstract
- Simultaneous measurements of the K-p→Σ€0π0, and K-p→ Λπ0 cross sections below 100 MeV/c kaon momentum have been performed. The kaon beam delivered by the DAΦNE collider was exploited to detect K- absorptions on hydrogen atoms populating the gas mixture of the KLOE drift chamber. The cross sections are determined with the highest yet obtained precision in the low kaon momentum regime [sigma(K- p ->Sigma 0 pi 0) = 42.8 +/- 1.5(stat)(-2.0)(+2.4) (syst) mb and sigma(K- p -> 0 pi 0) = 31.0 +/- 0.5(stat)(-1.2)(+1.2) (syst) mb] impacting on pending questions in several fields, ranging from nuclear and particle physics, to astrophysics.
|
|
| 3. |
- Skorodko, Tatiana, et al.
(författare)
-
Measurement of the p n ---> p p pi0 pi- reaction in search of the ABC resonance
- 2012
-
Ingår i: Proceedings of 12th International Workshop on Production, properties and interaction of mesons (MESON 2012). - Les Ulis Cedex, France : EDP Sciences. ; , s. 09033-
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- With pd collisions at T_p = 1.2 GeV exclusive measurements of the quasi-free pn -> pppi^0pi^- reaction have been carried out. Using the WASA detector setup at COSY total and differential cross sections have been obtained for the energy region &radics = 2.35 - 2.48 GeV. Though this includes the region of the ABC effect and its associated resonance structure, no low-mass enhancement (ABC effect) is found in the pi^0pi^--invariant mass spectrum - in agreement with the constraint from Bose statistics demanding the isovector pion pair to be in relative p-wave. Conventional calculations including t-channel processes for Roper, Delta(1600) and DeltaDelta excitations and their decays, which are well-known from the study of the two-pion production in pp collisions, provide a reasonable description of the data at high energies, but fall low at low energies. From this we conclude that a large contribution from a so far unknown isoscalar low-energy process is missed in the calculations. Inclusion of the ABC resonance at m = 2.37 GeV with Gamma = 70 MeV and I(J^P) = 0(3^+), which was recently observed in the pn -> dpi^0pi^0 reaction, leads to a much improved description of the data at low energies.
|
|
