| 1. |
- Engström, Gunnar, et al.
(författare)
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Pulmonary function and atherosclerosis in the general population : causal associations and clinical implications
- 2024
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Ingår i: European Journal of Epidemiology. - : Springer Nature. - 0393-2990 .- 1573-7284. ; 39:1, s. 35-49
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Tidskriftsartikel (refereegranskat)abstract
- Reduced lung function is associated with cardiovascular mortality, but the relationships with atherosclerosis are unclear. The population-based Swedish CArdioPulmonary BioImage study measured lung function, emphysema, coronary CT angiography, coronary calcium, carotid plaques and ankle-brachial index in 29,593 men and women aged 50–64 years. The results were confirmed using 2-sample Mendelian randomization. Lower lung function and emphysema were associated with more atherosclerosis, but these relationships were attenuated after adjustment for cardiovascular risk factors. Lung function was not associated with coronary atherosclerosis in 14,524 never-smokers. No potentially causal effect of lung function on atherosclerosis, or vice versa, was found in the 2-sample Mendelian randomization analysis. Here we show that reduced lung function and atherosclerosis are correlated in the population, but probably not causally related. Assessing lung function in addition to conventional cardiovascular risk factors to gauge risk of subclinical atherosclerosis is probably not meaningful, but low lung function found by chance should alert for atherosclerosis.
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| 2. |
- Bergström, Göran, 1964, et al.
(författare)
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Prevalence of Subclinical Coronary Artery Atherosclerosis in the General Population
- 2021
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Ingår i: Circulation. - Philadelphia : American Heart Association. - 0009-7322 .- 1524-4539. ; 144:12, s. 916-929
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Tidskriftsartikel (refereegranskat)abstract
- Background: Early detection of coronary atherosclerosis using coronary computed tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA to determine the prevalence, severity, and characteristics of coronary atherosclerosis and its association with CAC scores in a general population.Methods: We recruited 30 154 randomly invited individuals age 50 to 64 years to SCAPIS (the Swedish Cardiopulmonary Bioimage Study). The study includes individuals without known coronary heart disease (ie, no previous myocardial infarctions or cardiac procedures) and with high-quality results from CCTA and CAC imaging performed using dedicated dual-source CT scanners. Noncontrast images were scored for CAC. CCTA images were visually read and scored for coronary atherosclerosis per segment (defined as no atherosclerosis, 1% to 49% stenosis, or ≥50% stenosis). External validity of prevalence estimates was evaluated using inverse probability for participation weighting and Swedish register data.Results: In total, 25 182 individuals without known coronary heart disease were included (50.6% women). Any CCTA-detected atherosclerosis was found in 42.1%; any significant stenosis (≥50%) in 5.2%; left main, proximal left anterior descending artery, or 3-vessel disease in 1.9%; and any noncalcified plaques in 8.3% of this population. Onset of atherosclerosis was delayed on average by 10 years in women. Atherosclerosis was more prevalent in older individuals and predominantly found in the proximal left anterior descending artery. Prevalence of CCTA-detected atherosclerosis increased with increasing CAC scores. Among those with a CAC score >400, all had atherosclerosis and 45.7% had significant stenosis. In those with 0 CAC, 5.5% had atherosclerosis and 0.4% had significant stenosis. In participants with 0 CAC and intermediate 10-year risk of atherosclerotic cardiovascular disease according to the pooled cohort equation, 9.2% had CCTA-verified atherosclerosis. Prevalence estimates had excellent external validity and changed marginally when adjusted to the age-matched Swedish background population.Conclusions: Using CCTA in a large, random sample of the general population without established disease, we showed that silent coronary atherosclerosis is common in this population. High CAC scores convey a significant probability of substantial stenosis, and 0 CAC does not exclude atherosclerosis, particularly in those at higher baseline risk.
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| 3. |
- Eriksson, Clas, et al.
(författare)
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Economic Growth, Inequality, Democratization, and the Environment
- 2003
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Ingår i: Environmental and Resource Economics. - : Springer. - 0924-6460 .- 1573-1502. ; 25:1, s. 1-16
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Tidskriftsartikel (refereegranskat)abstract
- We augment the Stokey (1998) model by allowingagents to differ with respect to environmentalquality and income in order to analyze theimpact of income and environmental inequality,and of democratization on aggregate pollution.We find that the impact of a more equal incomedistribution depends on the degree ofdemocracy. In a complete democracy a more equalincome distribution generates, ceterisparibus, less pollution, which is consistentwith indirect empirical evidence, whereas theopposite is the case if democratic rights arehighly restricted. Furthermore, ademocratization is argued to typically lowerboth the income and the environmental qualityof the median voter. In this case, if, inutility terms, the fall in environmentalquality is worse than the fall in consumptionthe median voter decides to tightenenvironmental legislation so that aggregatepollution decreases.
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| 4. |
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| 5. |
- Gullö, Jan-Olof, 1961-, et al.
(författare)
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Nobel Creations
- 2015
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Ingår i: <em></em>. - Aalborg : Aalborg universitet.
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Konferensbidrag (refereegranskat)
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| 6. |
- Gullö, Jan-Olof, 1961-, et al.
(författare)
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Nobel Creations : Producing infinite music for an exhibition
- 2015
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Ingår i: Dansk Musikforskning Online. - Aalborg : Danish Musicology Online - DMO. - 1904-237X. ; :Special ed., s. 63-80
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Tidskriftsartikel (refereegranskat)abstract
- In 2014 a collaborative artistic music production project gave rise to the development and use of new methods for composition and music production. With a specially de- signed software engine the music productions responded interactively to actions of the visitors at the Nobel Museum in Stockholm. The music was distributed by multi- ple loudspeakers in the museum hall, week after week without interruption through the four months the exhibition lasted. The results of the project show clear evidence, that the romantic ideal, that creativity and creative capacity primarily is individual, in- born and inherent, is not valid. Instead, by combining different art forms, using struc- tured project planning, aiming to develop creative actions, people can create artwork in collaboration, that far exceeds what they individually can achieve.
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| 7. |
- Gustavsson Tingvall, Patrik, et al.
(författare)
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Geography, Cost-of-Living, and Determinants to Economic Growth : A Study of the Swedish Regions, 1911-1993
- 2003
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This paper analyses determinants to economic growth with a spatial perspective using data on the Swedish counties for the period 1911-1993. We find that the county growth rate of income per capita is strongly related to the growth rate of income per capita in contiguous counties regardless of what explanatory variables are included in the regressions. We also find empirical evidence of geographical spillovers through the income per capita and market size in contiguous counties. In addition, we find that population density and population age structure impact the growth rate of income per capita only when incomes are not adjusted for regional differences in cost-of-living. When correctly adjusting for such differences, which rarely occur in the growth literature that uses regional data, the growth effects of these variables disappear. The regressions also show that the estimated growth effect of net in-migration is negative and statistically significant.
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| 8. |
- Henriksson, Lilian, et al.
(författare)
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The transluminal attenuation gradient does not add diagnostic accuracy to coronary computed tomography
- 2021
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Ingår i: Acta Radiologica. - : Sage Publications. - 0284-1851 .- 1600-0455. ; , s. 867-874
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Tidskriftsartikel (refereegranskat)abstract
- Background A method for improving the accuracy of coronary computed tomography angiography (CCTA) is highly sought after as it would help to avoid unnecessary invasive coronary angiographies. Measurement of the transluminal attenuation gradient (TAG) has been proposed as an alternative to other existing methods, i.e. CT perfusion and CT fractional flow reserve (FFR). Purpose To evaluate the incremental value of three types of TAG in high-pitch spiral CCTA with invasive FFR measurements as reference. Material and Methods TAG was measured using two semi-automatic methods and one manual method. A receiver operating characteristic (ROC) analysis was made to determine the usefulness of TAG alone as well as TAG combined with CCTA for detection of significant coronary artery stenoses defined by an invasive FFR value <= 0.80. Results A total of 51 coronary vessels in 37 patients were included in this retrospective study. Hemodynamically significant stenoses were found in 13 vessels according to FFR. The ROC analysis TAG alone resulted in areas under the curve (AUCs) of 0.530 and 0.520 for the semi-automatic TAG and 0.557 for the manual TAG. TAG and CCTA combined resulted in AUCs of 0.567, 0.562 for semi-automatic TAG, and 0.569 for the manual TAG. Conclusion The results from our study showed no incremental value of TAG measured in single heartbeat CCTA in determining the severity of coronary artery stenosis degrees.
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| 9. |
- Persson, Joakim, 1961-
(författare)
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Convergence across the Swedish counties, 1911–1993
- 1997
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Ingår i: European Economic Review. - : Elsevier. - 0014-2921 .- 1873-572X. ; 41:9, s. 1835-1852
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Tidskriftsartikel (refereegranskat)abstract
- This paper finds strong and robust evidence of convergence in per capita income across the twenty-four Swedish counties, 1911–1993. In contrast to most previous studies on regional convergence this study adjusts incomes to account for regional differences in the cost of living. The main conclusion is that using adjusted incomes as opposed to non-adjusted incomes does not qualitatively change the results on convergence for the Swedish counties. However, a quantitative difference is that estimated speeds of convergence are higher and the standard deviation of the log of per capita income is lower when adjusted incomes are used, which is consistent with cross-country evidence.
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| 10. |
- Persson, Joakim, et al.
(författare)
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Does income inequality worsen pollution? The GEMS air pollution data revisited
- 2023
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Ingår i: Journal of Cleaner Production. - : ELSEVIER SCI LTD. - 0959-6526 .- 1879-1786. ; 422
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Tidskriftsartikel (refereegranskat)abstract
- Research on the effect of income inequality on pollution shows mixed results. This paper takes a new look at the urban air pollution data set of the U.N.'s Global Environmental Monitoring System (GEMS). We investigate the impact of income inequality on urban air pollution and relate the results to a median-voter model. In this model, more income inequality decreases the median income, reduces pollution controls, and increases output and pollution when the median income is above a threshold. We find that income inequality, measured by the Gini coefficient, increases SO2 concentration in the rich democracies. The estimated effects are non-negligible in size. For the poor non-democracies, we find no evidence that the Gini coefficient impacts SO2 concentration. The Gini coefficient is estimated to increase the smoke concentration at the five- or ten-percent significance level in most specifications in a pooled sample. We find no evidence that the Gini coefficient impacts the concentration of particulates in a pooled sample. We conclude that the empirical results largely are consistent with the medianvoter model.
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