| 1. |
- Kehoe, Laura, et al.
(författare)
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Make EU trade with Brazil sustainable
- 2019
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Persson, Marta, 1979, et al.
(författare)
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Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma.
- 2012
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Ingår i: Genes, chromosomes & cancer. - : Wiley. - 1098-2264 .- 1045-2257. ; 51:8, s. 805-17
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Tidskriftsartikel (refereegranskat)abstract
- Adenoid cystic carcinoma (ACC) of the head and neck is a malignant tumor with poor long-term prognosis. Besides the recently identified MYB-NFIB fusion oncogene generated by a t(6;9) translocation, little is known about other genetic alterations in ACC. Using high-resolution, array-based comparative genomic hybridization, and massively paired-end sequencing, we explored genomic alterations in 40 frozen ACCs. Eighty-six percent of the tumors expressed MYB-NFIB fusion transcripts and 97% overexpressed MYB mRNA, indicating that MYB activation is a hallmark of ACC. Thirty-five recurrent copy number alterations (CNAs) were detected, including losses involving 12q, 6q, 9p, 11q, 14q, 1p, and 5q and gains involving 1q, 9p, and 22q. Grade III tumors had on average a significantly higher number of CNAs/tumor compared to Grade I and II tumors (P = 0.007). Losses of 1p, 6q, and 15q were associated with high-grade tumors, whereas losses of 14q were exclusively seen in Grade I tumors. The t(6;9) rearrangements were associated with a complex pattern of breakpoints, deletions, insertions, inversions, and for 9p also gains. Analyses of fusion-negative ACCs using high-resolution arrays and massively paired-end sequencing revealed that MYB may also be deregulated by other mechanisms in addition to gene fusion. Our studies also identified several down-regulated candidate tumor suppressor genes (CTNNBIP1, CASP9, PRDM2, and SFN) in 1p36.33-p35.3 that may be of clinical significance in high-grade tumors. Further, studies of these and other potential target genes may lead to the identification of novel driver genes in ACC.
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| 6. |
- Persson, Sven, et al.
(författare)
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Forskningscirkeln på Augustenborgsskolan
- 2008
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Ingår i: Forskningscirklar i praktiken. - : Malmö stad. ; , s. 7-16
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Kapitlet handlar om hur forskningscirkeln genomfördes, vad som fokuserades under de olika terminer som cirkeln varade och vilken litteratur som lästes. Processen om hur de olika lärarnas forskningsprojekt växte fram beskrivs.
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| 7. |
- Svanberg, Sune, et al.
(författare)
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Applications of terawatt lasers
- 1994
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Ingår i: LASER SPECTROSCOPY - XITH INTERNATIONAL CONFERENCE. - : AIP. - 1551-7616 .- 0094-243X. - 1563962624 ; :290, s. 264-269
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Konferensbidrag (refereegranskat)
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| 8. |
- Abbasi, Alireza, et al.
(författare)
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Highly hydrated cations : Deficiency, mobility and coordination of water in crystalline nonahydrated scandium(III), yttrium(III) and lanthanoid(III) trifluoromethanesulfonate
- 2005
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Ingår i: Chemistry - A European Journal. - : Wiley. - 0947-6539 .- 1521-3765. ; 11:14, s. 4065-4077
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Tidskriftsartikel (refereegranskat)abstract
- Trivalent lanthanide-like metal ions coordinate nine water oxygen atoms, which form a tricapped trigonal prism in a large number of crystalline hydrates. Water deficiency, randomly distributed over the capping positions, was found for the smallest metal ions in the isomorphous nonahydrated trifluoromethanesulfonates, [M(H2O)(n)]CF3SO3)(3), in which M=Sc-III, Lu-III, Yb-III, Tm-III or Er-III. The hydration number n increases (n=8.0(1), 8.4(1), 8.7(1), 8.8(1) and 8.96(5), respectively) with increasing ionic size. Deuterium (H-2) solid-state NMR spectroscopy revealed fast positional exchange between the coordinated capping and prism water molecules; this exchange started at temperatures higher than about 280 K for lutetium(m) and below 268 K for scandium(m). Similar positional exchange for the fully nonahydrated yttrium(m) and lanthanum(m) compounds started at higher temperatures, over about 330 and 360 K, respectively. An exchange mechanism is proposed that can exchange equatorial and capping water molecules within the restrictions of the crystal lattice, even for fully hydrated lanthanoid(III) ions. Phase transitions occurred for all the water-deficient compounds at; 185 K. The hydrated scandium(III) trifluoromethanesulfonate transforms reversibly (Delta H degrees= -0.80(1) kJ mol(-1) on cooling) to a trigonal unit cell that is almost nine times larger, with the scandium ion surrounded by seven fully occupied and two partly occupied oxygen atom positions in a distorted capped trigonal prism. The hydrogen bonding to the trifluoromethanesulfonate anions stabilises the trigonal prism of water ligands, even for the crowded hydration sphere of the smallest metal ions in the series. Implications for the Lewis acid catalytic activity of the hydrated scandium(III) and lanthanoid(III) trifluoromethanesulfonates for organic syntheses performed in aqueous media are discussed.
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| 9. |
- Abdulgadir, Alamin, et al.
(författare)
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Performance Simulation of a Composite Filter Material Containing Mechanical Pulp Fibers, Microfibrillated Cellulose, and Cellulose Nanofibers
- 2022
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Ingår i: Proceedings of the International Mechanical Pulping Conference. ; , s. 160-
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Nonwoven fibrous materials with reticular support of an interconnected fiber network and a tortuous airflow pathway have been commonly used in filtration applications. To meet the criteria of filter efficiency and performance, the filter materials are recommended to contain different types of fibers such as mechanical pulp fibers, microfibrillated cellulose, cellulose nanofibers, and other polymer or synthetic fibers with a range of dimensions, i.e., length and diameter. Cellulose fibers in filter media possess irregular and complex structures with hollow or collapsed lumen structures owing to their refinement or pulping method. The development of an appropriate filter media model requires information on actual fiber characteristics. In this study, a simulation method was used to investigate the complex microstructures of filter media. The physical parameters such as fiber wall thickness, diameter, length, cross-section shapes, and curliness were obtained from fiber analyzers and scanning electron microscopy. Based on the experimental findings, GeoDict database comprising different types of common fiber models was constructed. 3-Dimensional fibrous models corresponding to the wet-laid binderless filter material were generated. Using the GeoDict modules, the pore size distributions, average pore sizes, air permeability, pressure drop and initial filter efficiency simulations were performed. The simulation results appear to be in close agreement with the experimental results. The incorporation of cellulose nanofibers resulted in reduced average pore sizes and air permeability of the filter material, thus enhancing the initial filter efficiency. The filter media developed a biobased material derived from pulp fibers for advanced applications such as medical facemask, and air filtration purposes.
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| 10. |
- Ackesjö, Helena, 1973-, et al.
(författare)
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Barns erfarenheter av sociala gemenskaper i övergångarna till och från förskoleklass
- 2014
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Ingår i: Pedagogisk forskning i Sverige. - : Institutionen för pedagogik och didaktik, Göteborgs universitet. - 1401-6788 .- 2001-3345. ; 19:1, s. 5-30
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Tidskriftsartikel (refereegranskat)abstract
- Tidigare forskning har visat att splittringar i barns relationer är en negativ faktor för barn i övergången från förskola till skola. Syftet med denna studie är att vinna kunskap om hur barn resonerar om övergångarna till och från förskoleklassen, och hur övergångarna inverkar på barnens kamratrelationer och tillhörighet i sociala gemenskaper. Studien är en etnografisk longitudinell studie, där samtal med barnen under 1,5 år i tre olika skolformer utgör det empiriska fundamentet. Resultaten visar att övergångar mellan skolformer innebär en relationell påfrestning för barn, där deras upplevelse av tillhörighet i sociala gemenskaper sätts på prov. I studien presenteras två aspekter av diskontinuitet mellan skolformer; den sociala och den fysiskt rumsliga. I linje med studiens resultat finns fog att vidare reflektera över hur barns tillhörighet i sociala gemenskaper villkoras av ständiga förändringar i gruppsammansättningar i samband med övergångarna, och hur det kan vara möjligt att förebygga ofrivilliga avbrott i barns relationer. I studien framstår förskoleklassen som en plats med begränsade möjligheter för sociala gemenskaper – ett år av övergångar till och övergångar från. Det kan därför vara relevant att vidare reflektera över förskoleklassens uppdrag att främja barns sociala gemenskaper.
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