| 1. |
- Bryhn, Andreas, et al.
(författare)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2019 : Resursöversikt
- 2020
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Fisken i havet är en resurs som rör sig fritt över nationella gränser. EU har därför en gemensam fiskeripolitik (GFP). Många arter som är viktiga för Sverige regleras inte i GFP och förvaltas därför nationellt.Denna rapport syftar till att:beskriva utvecklingen av fiskeripolitikenförklara den nuvarande politikens mål och regelverk och dess relation till mål och regler på miljöområdetförklara politikens nationella genomförande och det nationella handlingsutrymmetexemplifiera hur Havs- och vattenmyndigheten arbetat med att reglera fisket.
|
|
| 2. |
- Bryhn, Andreas, et al.
(författare)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2020 : Resursöversikt
- 2021
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- I rapporten kan du ta del av bedömningen som görs av situationen för bestånd som regleras inom ramen för EU:s gemensamma fiskeripolitik (GFP). Bedömningarna baseras på det forskningssamarbete och den rådgivning som sker inom det Internationella Havsforskningsrådet (ICES). Totalt redovisas underlag och råd för 48 fisk- och skaldjursarter.De bestånd som förvaltas nationellt baseras på de biologiska underlagen, och rådgivningen i huvudsak på den forskning och övervakning samt analys som bedrivs av Institutionen för akvatiska resurser vid Sveriges lantbruksuniversitet (SLU Aqua) samt yrkesfiskets rapportering.
|
|
| 3. |
- Dehlaghi Jadid, Kaveh, 1985-, et al.
(författare)
-
Long term oncological outcomes for laparoscopic versus open surgery for rectal cancer - A population-based nationwide noninferiority study
- 2022
-
Ingår i: Colorectal Disease. - : Wiley. - 1462-8910 .- 1463-1318. ; 24:11, s. 1308-1317
-
Tidskriftsartikel (refereegranskat)abstract
- Aim The aim of this work was to compare the 5-year overall survival in a national cohort of patients undergoing curative abdominal resection for rectal cancer by laparoscopic (LAP) or open (OPEN) surgery. Method All patients diagnosed with clinical Stage I-III rectal cancer and who underwent LAP or OPEN abdominal curative surgery in Sweden between 2010 and 2016 were retrieved from the Swedish Colorectal Cancer Registry. A noninferiority study design was employed with a statistical power of 90%, a one-side type I error of 2.5% and a noninferiority margin of 2%. The analyses were performed as intention-to-treat and the relationship between surgical technique and overall mortality within 5 years was analysed. Multilevel regression models with the patients matched by propensity scores adjusted for patient- and tumour-related variables were used. Results A total of 8410 Stage I-III cancer patients were included. This group underwent 2094 LAP (24.9%) and 6316 OPEN (75.1%) procedures and were followed until 31 December 2020. Multivariable Cox regression demonstrated that 5-year overall survival was higher in the LAP group [hazard ratio (HR) 0.877; 95% CI 0.877-0.993]. The outcome was similar when multiple imputation and propensity score matching were employed. When cT4 patients were excluded there was no difference (HR 0.885; 95% CI 0.790-1.033). At 5-years' follow-up local recurrence was not different, at 2.9% for the LAP group and 3.6% for the OPEN group (p = 0.075), while metastatic disease was more frequent in the OPEN group (19.6% compared with 15.6% for LAP; p < 0.001). Conclusion This study demonstrated that the LAP technique was not inferior to OPEN surgery with regard to overall 5-year survival. These results support the use of laparoscopic surgery.
|
|
| 4. |
- Dehlaghi Jadid, Kaveh, 1985-, et al.
(författare)
-
Long-term oncological outcomes for minimally invasive surgery versus open surgery for colon cancer-a population-based nationwide study with a non-inferiority design
- 2023
-
Ingår i: Colorectal Disease. - : Wiley. - 1462-8910 .- 1463-1318. ; 25:5, s. 954-963
-
Tidskriftsartikel (refereegranskat)abstract
- AimThe study aimed to compare 5-year overall survival in a national cohort of patients undergoing curative abdominal resection for colon cancer by minimally invasive surgery (MIS) or by the open (OPEN) technique. MethodsAll patients diagnosed between 2010 and 2016 in Sweden with pathological Union International Contre le Cancer Stages I-III colon cancer localized in the caecum, ascending colon, hepatic flexure or sigmoid colon and those who underwent curative right sided hemicolectomy, sigmoid resection or high anterior resection by MIS or OPEN were included. Patients were identified in the Swedish Colorectal Cancer Registry from which all data were retrieved. The analyses were performed as intention-to-treat and the relationship between surgical technique (MIS or OPEN) and overall mortality within 5 years was analysed. For the primary research question a non-inferiority hypothesis was assumed with a statistical power of 90%, a one-side type I error of 2.5% and a non-inferiority margin of 2%. For the secondary analyses, multilevel survival regression models with the patients matched by propensity scores were employed, adjusted for patient- and tumour-related variables. ResultsA total of 11 605 pathological Union International Contre le Cancer Stages I-III patients were included with 3297 MIS (28.4%) and 8308 OPEN (71.6%) and were followed until 31 December 2020. The primary analysis demonstrated superiority for MIS compared to OPEN. The multilevel survival regression analyses confirmed that 5-year overall survival was higher in MIS with a hazard ratio of 0.874 (95% confidence interval 0.791-0.965), and if excluding pT4 the outcome was similar, with a hazard ratio of 0.847 (95% confidence interval 0.756-0.948). ConclusionThis observational study demonstrated that MIS was favourable to OPEN with regard to 5-year overall survival. These results support the use of laparoscopic colon cancer surgery in routine practice.
|
|
| 5. |
- Granlund, Alexander, et al.
(författare)
-
Evaluation of Local Conditions and Their Impact on Bifacial PV Performance at High Latitude
- 2022
-
Konferensbidrag (refereegranskat)abstract
- Different conditions such as module orientation, ground albedo, shading and latitude are known to affect the performance of bifacial photovoltaic modules. We evaluate bifacial performance for one year at a site located at 65°N through comparison of measured and simulated front and back side plane-of-array irradiation. Each investigated module has a different azimuth, tilt, and exposure to shading from the surroundings. Local shading is found to severely impact the energy yield of the site in general, and individual modules to a varying degree depending on their location and orientation. Proper shading analysis appears to be required in the planning phase of a bifacial photovoltaic installation to accurately calculate the expected energy yield. The bifacial gain of the modules with azimuths in the east–west sector is found to span a range from 16 % to approximately the bifaciality factor, depending on the orientation. To fully utilize the potential of bifacial photovoltaics, this variability also needs to be carefully considered when planning and building bifacial photovoltaic installations.
|
|
| 6. |
- Petersson, Josefin, et al.
(författare)
-
Bowel Obstruction and Ventral Hernia After Laparoscopic Versus Open Surgery for Rectal Cancer in A Randomized Trial (COLOR II).
- 2019
-
Ingår i: Annals of surgery. - 1528-1140. ; 269:1, s. 53-57
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to evaluate the risk of bowel obstruction, incisional, and parastomal hernia following laparoscopic versus open surgery for rectal cancer.Laparoscopic surgery for rectal cancer has been adopted worldwide, after trials reported similar oncological outcomes compared with open surgery. Little is known about long-term morbidity, including bowel obstruction, incisional, and parastomal hernia following surgery.Patients included in the international, multicenter, noninferior, open-label, randomized COLOR II trial were followed for five years. Primary endpoint was local recurrence at 3-year follow-up. Secondary endpoints included bowel obstruction, incisional and parastomal hernia within 5 years, and the current article reports on these secondary endpoints.All 1044 patients included in the COLOR II trial were analyzed. There was no difference in risk of bowel obstruction, incisional, or parastomal hernia following laparoscopic or open surgery for rectal cancer.Based on long-term morbidity outcomes, laparoscopic surgery for rectal cancer could be considered a routine technique as there are no differences with open surgery.
|
|
| 7. |
- Petersson, Josefin, et al.
(författare)
-
Increasing incidence of colorectal cancer among the younger population in Sweden
- 2020
-
Ingår i: Bjs Open. - : Oxford University Press (OUP). - 2474-9842. ; 4:4, s. 645-658
-
Tidskriftsartikel (refereegranskat)abstract
- Background The incidence of colorectal cancer in patients aged less than 50 years is increasing in Western countries. This population-based study investigated the age- and sex-specific incidence of colorectal cancer over time in Sweden, and characterized trends in tumour localization and stage at diagnosis. Methods Patients diagnosed with colorectal cancer between 1970 and 2016 were identified from the Swedish Cancer Registry, and categorized by sex, age and tumour location. The incidence and average annual percentage change (AAPC) were estimated and compared between age groups. Results There was an overall increase in the incidence of colorectal cancer between 1970 and 2006, but a decrease in 2006-2016 (AAPC -0.55 (95 per cent c.i. -1.02 to -0.07) per cent). The largest increase in colonic cancer was in 1995-2005 in women aged less than 50 years (AAPC 2.30 (0.09 to 4.56) per cent versus 0.04 (-1.35 to 1.44) and - 0.67 (-1.62 to 0.28) per cent in women aged 50-74 and 75 years or more respectively). Since 1990, rectal cancer increased in patients of both sexes aged below 50 years, with higher AAPC values in women (2006-2016: 2.01 (-1.46 to 5.61) per cent versus 0.20 (-2.25 to 2.71) per cent in men). Younger patients were more likely than those aged 50-74 and 75 years or more to present with stage III-IV colonic (66.2, 57.6 and 49.6 per cent respectively) and rectal (61.2, 54.3 and 51.3 per cent) cancer. From the mid 1990s, rates of proximal and distal colorectal cancer, and rectal cancer were increased in patients aged less than 50 years. Conclusion The overall incidence of colorectal cancer in Sweden decreased in the past decade. However, in patients under 50 years of age the incidence of colorectal cancer - proximal, distal and rectal - continued to increase over time.
|
|
| 8. |
- Petersson, Josefin
(författare)
-
lncidence of Colorectal Cancer and Comparisons of Outcomes after Minimally Invasive and Open Surgery
- 2023
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Aim: Surgery remains the mainstay of treatment for colorectal cancer. The aim of this thesis was to determine the overall incidence of colorectal cancer in Sweden over time and to evaluate surgical treatment comparing minimally invasive surgery including laparoscopic and robot assisted laparoscopic surgery to open surgery. Methods: Paper I explores the overall incidence of colorectal cancer in Sweden over time. Papers II-IV report results from two population based cohort studies and a randomized controlled trial. The papers compare minimally invasive surgery including laparoscopic and robot assisted laparoscopic surgery to open surgery for colon and rectal cancer. Results: Paper I found a decrease in the overall incidence of colorectal cancer in Sweden in the last decade, whilst the incidence in patients under the age of 50 years continued to increase. Paper II demonstrated favorable short-term outcomes following laparoscopic surgery compared to open surgery for colon cancer. Paper III showed that minimally invasive surgery for rectal cancer was non-inferior to open surgery with regard to adequate cancer resection with advantageous short-term outcomes. There were no long-term difference in risk of bowel obstruction, incisional, or parastomal hernia comparing the surgical techniques in patients with rectal cancer as reported in paper IV. Conclusion: The overall incidence of colorectal cancer in Sweden has decreased in the last decade, despite an increase in the younger population. Surgical resection for colorectal cancer using minimally invasive technique is oncologically safe with favorable short-term outcomes compared to open surgery. No advantage was found following minimally invasive surgery for rectal cancer with regard to long-term risk of bowel obstruction, incisional and parastomal hernia.
|
|
| 9. |
- Petersson, Josefin, et al.
(författare)
-
Short term results in a population based study indicate advantage for laparoscopic colon cancer surgery versus open
- 2023
-
Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 13:1
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to compare LAP with OPEN regarding short-term mortality, morbidity and completeness of the cancer resection for colon cancer in a routine health care setting using population based register data. All 13,683 patients who were diagnosed 2012-2018 and underwent elective surgery for right-sided or sigmoid colon cancer were included from the Swedish Colorectal Cancer Registry and the National Patient Registry. Primary outcome was 30-day mortality. Secondary outcomes were 90-day mortality, length of hospital stay, reoperation, readmission and positive resection margin (R1). Weighted and unweighted multi regression analyses were performed. There were no difference in 30-day mortality: LAP (0.9%) and OPEN (1.3%) (OR 0.89, 95% CI 0.62-1.29, P = 0.545). The weighted analyses showed an increased 90-day mortality following OPEN, P < 0.001. Re-operations and re-admission were more frequent after OPEN and length of hospital stay was 2.9 days shorter following LAP (P < 0.001). R1 resections were significantly more common in the OPEN group in the unweighted and weighted analysis with P = 0.004 and P < 0.001 respectively. Therefore, the favourable short-term outcomes following elective LAP versus OPEN resection for colon cancer in routine health care indicate an advantage of laparoscopic surgery.
|
|
| 10. |
- Petersson, Josefin, et al.
(författare)
-
Short-term results in a population based study indicate advantage for minimally invasive rectal cancer surgery versus open
- 2024
-
Ingår i: BMC Surgery. - : BioMed Central (BMC). - 1471-2482. ; 24:1
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The aim of this study was to determine if minimally invasive surgery (MIS) for rectal cancer is non-inferior to open surgery (OPEN) regarding adequacy of cancer resection in a population based setting.METHODS: All 9,464 patients diagnosed with rectal cancer 2012-2018 who underwent curative surgery were included from the Swedish Colorectal Cancer Registry.PRIMARY OUTCOMES: Positive circumferential resection margin (CRM < 1 mm) and positive resection margin (R1). Non-inferiority margins used were 2.4% and 4%. SECONDARY OUTCOMES: 30- and 90-day mortality, clinical anastomotic leak, re-operation < 30 days, 30- and 90-day re-admission, length of stay (LOS), distal resection margin < 1 mm and < 12 resected lymph nodes. Analyses were performed by intention-to-treat using unweighted and weighted multiple regression analyses.RESULTS: The CRM was positive in 3.8% of the MIS group and 5.4% of the OPEN group, risk difference -1.6% (95% CI -1.623, -1.622). R1 was recorded in 2.8% of patients in the MIS group and in 4.4% of patients in the OPEN group, risk difference -1.6% (95% CI -1.649, -1.633). There were no differences between the groups in adjusted unweighted and weighted analyses. All analyses demonstrated decreased mortality and re-admissions at 30 and 90 days as well as shorter LOS following MIS.CONCLUSIONS: In this population based setting MIS for rectal cancer was non-inferior to OPEN regarding adequacy of cancer resection with favorable short-term outcomes.
|
|
