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Sökning: WFRF:(Pfaff E)

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1.
  • Lissek, T, et al. (författare)
  • Building Bridges through Science
  • 2017
  • Ingår i: Neuron. - : Elsevier BV. - 1097-4199 .- 0896-6273. ; 96:4, s. 730-735
  • Tidskriftsartikel (refereegranskat)
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  • Fridlund, Malcolm, 1952, et al. (författare)
  • K2-111 b - A short period super-Earth transiting a metal poor, evolved old star
  • 2017
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 604, s. A16-
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. From a light curve acquired through the K2 space mission, the star K2-111(EPIC 210894022) has been identified as possibly orbited by a transiting planet. Aims: Our aim is to confirm the planetary nature of the object and derive its fundamental parameters. Methods: We analyse the light curve variations during the planetary transit using packages developed specifically for exoplanetary transits. Reconnaissance spectroscopy and radial velocity observations have been obtained using three separate telescope and spectrograph combinations. The spectroscopic synthesis package SME has been used to derive the stellar photospheric parameters that were used as input to various stellar evolutionary tracks in order to derive the parameters of the system. The planetary transit was also validated to occur on the assumed host star through adaptive imaging and statistical analysis. Results: The star is found to be located in the background of the Hyades cluster at a distance at least 4 times further away from Earth than the cluster itself. The spectrum and the space velocities of K2-111 strongly suggest it to be a member of the thick disk population. The co-added high-resolution spectra show that that it is a metal poor ([Fe/H] = - 0.53 ± 0.05 dex) and α-rich somewhat evolved solar-like star of spectral type G3. We find Teff = 5730 ± 50 K, log g⋆ = 4.15 ± 0.1 cgs, and derive a radius of R⋆ = 1.3 ± 0.1 R⊙ and a mass of M⋆ = 0.88 ± 0.02 M⊙. The currently available radial velocity data confirms a super-Earth class planet with a mass of 8.6 ± 3.9 M⊕ and a radius of 1.9 ± 0.2 R⊕. A second more massive object with a period longer than about 120 days is indicated by a long-term radial velocity drift. Conclusions: The radial velocity detection together with the imaging confirms with a high level of significance that the transit signature is caused by a planet orbiting the star K2-111. This planet is also confirmed in the radial velocity data. A second more massive object (planet, brown dwarf, or star) has been detected in the radial velocity signature. With an age of ≳10 Gyr this system is one of the oldest where planets are hitherto detected. Further studies of this planetary system are important since it contains information about the planetary formation process during a very early epoch of the history of our Galaxy.
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  • Hoffman, Lindsey M., et al. (författare)
  • Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG) : A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries
  • 2018
  • Ingår i: Journal of Clinical Oncology. - : AMER SOC CLINICAL ONCOLOGY. - 0732-183X .- 1527-7755. ; 36:19, s. 1963-1972
  • Tidskriftsartikel (refereegranskat)abstract
    • PurposeDiffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median survival of < 1 year. The International and European Society for Pediatric Oncology DIPG Registries collaborated to compare clinical, radiologic, and histomolecular characteristics between short-term survivors (STSs) and long-term survivors (LTSs).Materials and MethodsData abstracted from registry databases included patients from North America, Australia, Germany, Austria, Switzerland, the Netherlands, Italy, France, the United Kingdom, and Croatia.ResultsAmong 1,130 pediatric and young adults with radiographically confirmed DIPG, 122 (11%) were excluded. Of the 1,008 remaining patients, 101 (10%) were LTSs (survival 2 years). Median survival time was 11 months (interquartile range, 7.5 to 16 months), and 1-, 2-, 3-, 4-, and 5-year survival rates were 42.3% (95% CI, 38.1% to 44.1%), 9.6% (95% CI, 7.8% to 11.3%), 4.3% (95% CI, 3.2% to 5.8%), 3.2% (95% CI, 2.4% to 4.6%), and 2.2% (95% CI, 1.4% to 3.4%), respectively. LTSs, compared with STSs, more commonly presented at age < 3 or > 10 years (11% v 3% and 33% v 23%, respectively; P < .001) and with longer symptom duration (P < .001). STSs, compared with LTSs, more commonly presented with cranial nerve palsy (83% v 73%, respectively; P = .008), ring enhancement (38% v 23%, respectively; P = .007), necrosis (42% v 26%, respectively; P = .009), and extrapontine extension (92% v 86%, respectively; P = .04). LTSs more commonly received systemic therapy at diagnosis (88% v 75% for STSs; P = .005). Biopsies and autopsies were performed in 299 patients (30%) and 77 patients (10%), respectively; 181 tumors (48%) were molecularly characterized. LTSs were more likely to harbor a HIST1H3B mutation (odds ratio, 1.28; 95% CI, 1.1 to 1.5; P = .002).ConclusionWe report clinical, radiologic, and molecular factors that correlate with survival in children and young adults with DIPG, which are important for risk stratification in future clinical trials.
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  • Albertin, S., et al. (författare)
  • Surface optical reflectance combined with x-ray techniques during gas-surface interactions
  • 2020
  • Ingår i: Journal of Physics D. - : Institute of Physics (IOP). - 0022-3727 .- 1361-6463. ; 53:22
  • Tidskriftsartikel (refereegranskat)abstract
    • High energy surface x-ray diffraction (HESXRD), x-ray reflectivity (XRR), mass spectrometry (MS) and surface optical reflectance (SOR) have been combined to simultaneously obtain sub-second information on the surface structure and morphology from a Pd(100) model catalyst during in situ oxidation at elevated temperatures and pressures resulting in Pd bulk oxide formation. The results show a strong correlation between the HESXRD and SOR signal intensities during the experiment, enabling phase determination and a time-resolved thickness estimation of the oxide by HESXRD, complemented by XRR measurements. The experiments show a remarkable sensitivity of the SOR to changes in the surface phase and morphology, in particular to the initial stages of oxidation/reduction. The data imply that SOR can detect the formation of an ultrathin PdO surface oxide layer of only 2-3 angstrom thickness.
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8.
  • Baylis, Kathy, et al. (författare)
  • Mainstreaming Impact Evaluation in Nature Conservation
  • 2016
  • Ingår i: Conservation Letters. - : Wiley. - 1755-263X. ; 9:1, s. 58-64
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • An important part of conservation practice is the empirical evaluation of program and policy impacts. Understanding why conservation programs succeed or fail is essential for designing cost-effective initiatives and for improving the livelihoods of natural resource users. The evidence we seek can be generated with modern impact evaluation designs. Such designs measure causal effects of specific interventions by comparing outcomes with the interventions to outcomes in credible counterfactual scenarios. Good designs also identify the conditions under which the causal effect arises. Despite a critical need for empirical evidence, conservation science has been slow to adopt these impact evaluation designs. We identify reasons for the slow rate of adoption and provide suggestions for mainstreaming impact evaluation in nature conservation.
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9.
  • Brenning, Nils, et al. (författare)
  • Critical ionization velocity interaction in the CRIT I rocket experiment
  • 1990
  • Ingår i: Advances in Space Research. - : Elsevier BV. - 0273-1177. ; 10, s. 63-66
  • Tidskriftsartikel (refereegranskat)abstract
    • In the rocket experiment CRIT I, launched from Wallops Island on 13 May 1986, two identical Barium shaped charges were fired from distances of 1.3 km and 3.6 km towards the main experiment payload, which was separated from a sub-payload by a couple of km along the magnetic field. The relevance of earlier proposed mechanisms for electron heating in ionospheric critical velocity experiments is investigated in the light of the CRIT I results. It is concluded that both the "homogeneous" and the "ionizing front" models can be applied, in different parts of the stream. It is also possible that a third, entirely different, mechanism may contribute to the electron heating. This mechanism involves direct energization of electrons in the magnetic-field-aligned component of the DC electric field. © 1989.
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10.
  • Brenning, Nils, et al. (författare)
  • Electrodynamic interaction between the CRIT I ionized barium streams and the ambient ionosphere
  • 1990
  • Ingår i: Advances in Space Research. - : Elsevier BV. - 0273-1177. ; 10, s. 67-70
  • Tidskriftsartikel (refereegranskat)abstract
    • In the CRIT I Critical Velocity experiment, launched from Wallops Island on 13 May, 1986, two fast barium streams were ejected by means of shaped charges. Their electrodynamic interaction with the ambient ionosphere is discussed. An outstanding feature of the DC electric field observed within the streams was a large magnetic-field-aligned component, persisting on the time scale of the passage of the streams. One interpretation of the DC electric field data is that the internal electric fields of the streams is not greatly modified by Birkeland currents, i.e. a state is established, where the transverse currents are to a first approximation divergence-free. It is argued that this interpretation can explain why a reversal of the strong explosion-directed electric field was observed in the first explosion but not in the second (more distant one). © 1989.
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