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Träfflista för sökning "WFRF:(Portillo M) "

Search: WFRF:(Portillo M)

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  • Bouyoucef, S E, et al. (author)
  • Poster Session 2 : Monday 4 May 2015, 08
  • 2015
  • In: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
  • Journal article (peer-reviewed)
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  • 2019
  • Journal article (peer-reviewed)
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  • Pantazis, N, et al. (author)
  • Determining the likely place of HIV acquisition for migrants in Europe combining subject-specific information and biomarkers data
  • 2019
  • In: Statistical methods in medical research. - : SAGE Publications. - 1477-0334 .- 0962-2802. ; 28:7, s. 1979-1997
  • Journal article (peer-reviewed)abstract
    • In most HIV-positive individuals, infection time is only known to lie between the time an individual started being at risk for HIV and diagnosis time. However, a more accurate estimate of infection time is very important in certain cases. For example, one of the objectives of the Advancing Migrant Access to Health Services in Europe (aMASE) study was to determine if HIV-positive migrants, diagnosed in Europe, were infected pre- or post-migration. We propose a method to derive subject-specific estimates of unknown infection times using information from HIV biomarkers’ measurements, demographic, clinical, and behavioral data. We assume that CD4 cell count (CD4) and HIV-RNA viral load trends after HIV infection follow a bivariate linear mixed model. Using post-diagnosis CD4 and viral load measurements and applying the Bayes’ rule, we derived the posterior distribution of the HIV infection time, whereas the prior distribution was informed by AIDS status at diagnosis and behavioral data. Parameters of the CD4–viral load and time-to-AIDS models were estimated using data from a large study of individuals with known HIV infection times (CASCADE). Simulations showed substantial predictive ability (e.g. 84% of the infections were correctly classified as pre- or post-migration). Application to the aMASE study ( n = 2009) showed that 47% of African migrants and 67% to 72% of migrants from other regions were most likely infected post-migration. Applying a Bayesian method based on bivariate modeling of CD4 and viral load, and subject-specific information, we found that the majority of HIV-positive migrants in aMASE were most likely infected after their migration to Europe.
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  • Result 1-10 of 45
Type of publication
journal article (37)
conference paper (5)
research review (2)
book chapter (1)
Type of content
peer-reviewed (43)
other academic/artistic (2)
Author/Editor
Riboli, Elio (9)
Overvad, Kim (8)
Boeing, Heiner (8)
Tumino, Rosario (8)
Tjønneland, Anne (7)
Key, Timothy J (7)
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Panico, Salvatore (7)
Kaaks, Rudolf (6)
Trichopoulou, Antoni ... (6)
Weiderpass, Elisabet ... (6)
Ardanaz, Eva (6)
Palli, Domenico (6)
Olsen, Anja (5)
Khaw, Kay-Tee (5)
Lötvall, Jan, 1956 (5)
Agudo, Antonio (5)
Wareham, Nicholas J. (5)
Langenberg, Claudia (5)
Wahlgren, M (4)
Skeie, Guri (4)
Boutron-Ruault, Mari ... (4)
Fagherazzi, Guy (4)
Menendez, C (4)
Melander, Olle (4)
Kühn, Tilman (4)
Quirós, J. Ramón (4)
Ferrari, Pietro (4)
Dorronsoro, Miren (4)
Mueller, I (4)
Zhang, L. (3)
Sharma, S. (3)
Krogh, Vittorio (3)
Yamada, Y. (3)
Wang, S. H. (3)
Nilsson, Peter M (3)
Saito, N (3)
Gunter, Marc J. (3)
Murphy, Neil (3)
Huerta, José Maria (3)
Schulze, Matthias B. (3)
Ricceri, Fulvio (3)
Ericson, Ulrika (3)
Matullo, Giuseppe (3)
Stepien, Magdalena (3)
Sonestedt, Emily (3)
Winkvist, Anna, 1962 (3)
Chen, J.H. (3)
Macauley, J (3)
Bardaji, A (3)
Martinez-Espinosa, F ... (3)
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University
Karolinska Institutet (23)
Lund University (19)
Umeå University (16)
University of Gothenburg (10)
Uppsala University (5)
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Chalmers University of Technology (3)
University of Gävle (2)
Swedish University of Agricultural Sciences (2)
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Language
English (45)
Research subject (UKÄ/SCB)
Medical and Health Sciences (21)
Natural sciences (15)
Engineering and Technology (1)
Agricultural Sciences (1)

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