| 1. |
- Pott, Christian, et al.
(författare)
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Bennettitales in the Rhaetian flora of Wüstenwelsberg, Bavaria, Germany
- 2016
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Ingår i: Review of Palaeobotany and Palynology. - Amsterdam : Elsevier. - 0034-6667 .- 1879-0615. ; 232, s. 98-118
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Tidskriftsartikel (refereegranskat)abstract
- The diverse bennettitalean plant remains from the Rhaetian of Wüstenwelsberg, Franconia, southern Germany,are described by means of macromorphological and epidermal anatomy; the study is part of the ongoing examinationof this recently excavated and excellently preserved fossil flora. The taxa identified include four species ofPterophyllum, one species of Anomozamites, two species of Nilssoniopteris and one species of Wielandiella withsterile leaves, bracts and ovulate reproductive organs. In addition, an enigmatic type of bennettitalean microsporangiateorgan has been obtained, remains of which from the Rhaetian of Greenland had been assigned toBennettistemon. However, the material from Wüstenwelsberg is much more complete and is assigned to a newgenus, viz. Welsbergia gen. nov., with its type species Welsbergia bursigera (Harris) comb. nov., based on theorgan's unique architecture. The microsporangiate organs are always exclusively associated with the sterile foliagePterophyllum aequale. Comparison of the flora fromWüstenwelsbergwith adjacent Rhaetian floras revealeddistinct local differences in the bennettitalean constitution, which are discussed in the light of palaeogeographyand plant dispersal patterns.
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| 2. |
- Pott, Christian, et al.
(författare)
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New data on Selaginellites coburgensis from the Rhaetian of Wüstenwelsberg (Upper Franconia, Germany).
- 2016
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Ingår i: Neues Jahrbuch für Geologie und Palaontologie - Abhandlungen. - Stuttgart : E. Schweizerbart'sche Verlagsbuchhandlung. - 0077-7749. ; 280, s. 177-181
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Tidskriftsartikel (refereegranskat)abstract
- A branched shoot with several attached microsporangiate strobili of the Rhaetian (late Triassic) herbaceous lycophyte Selaginellites coburgensis is described from Wüstenwelsberg near Coburg, Germany, the locus typicus of the species. The strobili all contain Uvaesporites-type microspores, precisely as the single, detached strobilus fragment found in association with one of the original specimens
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| 3. |
- Pott, Johanna, et al.
(författare)
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Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility
- 2012
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Ingår i: PLoS Pathogens. - : Public Library of Science (PLoS). - 1553-7366 .- 1553-7374. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- Rotavirus is a major cause of diarrhea worldwide and exhibits a pronounced small intestinal epithelial cell (IEC) tropism. Both human infants and neonatal mice are highly susceptible, whereas adult individuals remain asymptomatic and shed only low numbers of viral particles. Here we investigated age-dependent mechanisms of the intestinal epithelial innate immune response to rotavirus infection in an oral mouse infection model. Expression of the innate immune receptor for viral dsRNA, Toll-like receptor (Tlr) 3 was low in the epithelium of suckling mice but strongly increased during the postnatal period inversely correlating with rotavirus susceptibility, viral shedding and histological damage. Adult mice deficient in Tlr3 (Tlr3-/-) or the adaptor molecule Trif (TrifLps2/Lps2) exerted significantly higher viral shedding and decreased epithelial expression of proinflammatory and antiviral genes as compared to wild-type animals. In contrast, neonatal mice deficient in Tlr3 or Trif did not display impaired cell stimulation or enhanced rotavirus susceptibility. Using chimeric mice, a major contribution of the non-hematopoietic cell compartment in the Trif-mediated antiviral host response was detected in adult animals. Finally, a significant age-dependent increase of TLR3 expression was also detected in human small intestinal biopsies. Thus, upregulation of epithelial TLR3 expression during infancy might contribute to the age-dependent susceptibility to rotavirus infection. © 2012 Pott et al.
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