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Sökning: WFRF:(Preis Anna)

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1.
  • Botteldooren, Dick, et al. (författare)
  • From Sonic Environment to Soundscape
  • 2015
  • Ingår i: Soundscape and the Built Environment. - Boca Raton : CRC Press. - 9781482226317 - 9781482226324 ; , s. 17-41
  • Bokkapitel (refereegranskat)
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2.
  • Preis, Anna, et al. (författare)
  • Audio-visual interaction of environmental noise
  • 2016
  • Ingår i: Noise Control Engineering Journal. - 0736-2501 .- 2168-8710. ; 64:1, s. 34-43
  • Tidskriftsartikel (refereegranskat)abstract
    • Currently research into the psychological evaluation of noise in daily life is car- ried out without taking into account the sense of sight. The human senses interact with each other; thus some information coming from one sense can be skipped or ignored in favor of information coming from another sense, leading to completely different reactions or behavior. The aim of this paper is to verify, on the basis of psychophysical experiments, how a human being processes audio-visual informa- tion coming from the different environmental noises which can be encountered in daily life. The experiment was divided into three parts: auditory, visual, and audio-visual. In each part of the experiment, the ICBEN scale (0–10) was used to rate the presented stimuli. In the first part only audio stimuli were pre- sented, and subjects were asked to rate their annoyance with the sound. In the second part of the experiment, the participants were asked to rate how pleasant the presented video clips were. Finally, in the last part of the experiment, parti- cipants were presented with a compatible and incompatible mix of audio and visual stimuli and asked to rate their annoyance. We found that several audio stimuli were assessed differently, to a significant extent, by listeners after video clips were added to them. © 2016 Institute of Noise Control Engineering.
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3.
  • Schumann, Gunter, et al. (författare)
  • KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference
  • 2016
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 113:50, s. 14372-14377
  • Tidskriftsartikel (refereegranskat)abstract
    • Excessive alcohol consumption is a major public health problem worldwide. Although drinking habits are known to be inherited, few genes have been identified that are robustly linked to alcohol drinking. We conducted a genome-wide association metaanalysis and replication study among >105,000 individuals of European ancestry and identified beta-Klotho (KLB) as a locus associated with alcohol consumption (rs11940694; P = 9.2 x 10(-12)). beta-Klotho is an obligate coreceptor for the hormone FGF21, which is secreted from the liver and implicated in macronutrient preference in humans. We show that brain-specific beta-Klotho KO mice have an increased alcohol preference and that FGF21 inhibits alcohol drinking by acting on the brain. These data suggest that a liver-brain endocrine axis may play an important role in the regulation of alcohol drinking behavior and provide a unique pharmacologic target for reducing alcohol consumption.
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