SwePub - sökning: WFRF:(Putcha V)

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1.	Brisman, Jonas, 1954, et al. (författare) Exposure-response relations for work related respiratory symptoms and sensitisation in a cohort exposed to alpha-amylase. 2004 Ingår i: Occupational and environmental medicine. - 1470-7926. ; 61:6, s. 551-3 Tidskriftsartikel (refereegranskat)abstract AIMS: To explore relations between exposure to fungal alpha-amylase and the risk of new work related respiratory symptoms or sensitisation. METHODS: A prospective cohort study among 300 bakers and millers was followed up for a maximum of seven years. Exposure to alpha-amylase was estimated by air measurements and questionnaires and classified into three categories. Symptoms were recorded with a self-administered questionnaire and skin sensitisation assessed using skin prick test (SPT). RESULTS: There were 36 new cases of chest symptoms, 86 of eyes/nose symptoms, and 24 of a positive SPT to alpha-amylase. There were exposure-response relations for chest and eyes/nose symptoms and for sensitisation, and a significantly increased prevalence ratio for chest symptoms in the highest exposure category. CONCLUSION: A reduction in alpha-amylase exposure is likely to reduce the risk for respiratory morbidity in bakery workers.

Brisman, Jonas, 1954, et al. (författare)
Exposure-response relations for work related respiratory symptoms and sensitisation in a cohort exposed to alpha-amylase.
2004
Ingår i: Occupational and environmental medicine. - 1470-7926. ; 61:6, s. 551-3
Tidskriftsartikel (refereegranskat)abstract
- AIMS: To explore relations between exposure to fungal alpha-amylase and the risk of new work related respiratory symptoms or sensitisation. METHODS: A prospective cohort study among 300 bakers and millers was followed up for a maximum of seven years. Exposure to alpha-amylase was estimated by air measurements and questionnaires and classified into three categories. Symptoms were recorded with a self-administered questionnaire and skin sensitisation assessed using skin prick test (SPT). RESULTS: There were 36 new cases of chest symptoms, 86 of eyes/nose symptoms, and 24 of a positive SPT to alpha-amylase. There were exposure-response relations for chest and eyes/nose symptoms and for sensitisation, and a significantly increased prevalence ratio for chest symptoms in the highest exposure category. CONCLUSION: A reduction in alpha-amylase exposure is likely to reduce the risk for respiratory morbidity in bakery workers.

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