| 1. |
- Hyvarinen, Anne, et al.
(författare)
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Characterizing microbial exposure with ergosterol, 3-hydroxy fatty acids, and viable microbes in house dust: Determinants and association with childhood asthma
- 2006
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Ingår i: Archives of Environmental & Occupational Health. - 1933-8244. ; 61:4, s. 149-157
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Tidskriftsartikel (refereegranskat)abstract
- The authors assessed determinants of ergosterol, 3-OH fatty acids (FAs), and viable microbes in vacuum cleaner dust, and investioated the association between these microbial markets and childhood asthma. The authors studied the homes of 36 children who were new cases of childhood asthma and the homes of 36 controls. Home characteristics explained 34% to 44% of the variation in levels of different microbial groups. Determinants of 3-OH FAs were a lower level of cleanliness, having a fireplace, having livestock, and moisture damage; determinants of viable bacteria were the level of home repair needed and the material used in the building frame of the home. Ergosterol was associated with the presence of livestock and the practice of cleaning rugs outside; viable fungi was associated with the material used in the building frame, visible mold, and the practice of cleaning rugs Outside. Exposure to mesophilic actinonnycetes was nonsignificantly associated with risk of asthma. The authors Concluded that the variation of microbial levels in dust could be explained relatively well by home characteristics, and suggested that exposure to mesophilic actinomycetes may increase the risk of new asthma.
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| 2. |
- Wang, Juan, 1984-
(författare)
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Asthma and Rhinitis among Adults in Sweden and China : Risk Factors in the Home Environment
- 2018
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The main aim of this thesis was to evaluate associations between selected home environment factors and asthma, rhinitis and respiratory symptoms among adults from Sweden, China and northern Europe. Two studies were performed in Sweden, one in China, and one longitudinal cohort study was performed in northern Europe. Dampness/mould was common, and was a main risk factor in all studies. Other risk factors for asthma symptoms in Sweden included window pane condensation in winter, multi-family buildings constructed from 1961-1975, rented apartments, environment tobacco smoke (ETS), and living in a colder climate zone. Higher ventilation flow in Sweden was associated with less asthma symptoms. Risk factors for rhinitis in Sweden included window pane condensation, a higher moisture load, concrete slab foundation constructed before 1991, multi-family buildings constructed from 1976-1985, rented apartments and living in densely populated areas. Risk factors for rhinitis in China included window pane condensation, recent redecoration, new furniture, presence of cockroaches, pet keeping, ETS and living near a main road or highway. Frequently cleaning of the home and putting beddings to sunshine were protective factors for rhinitis in China. Other risk factors for respiratory infections in Sweden included houses with a brick façade, window pane condensation, a higher moisture load, multi-family buildings constructed from 1976-1985, rented apartments and living in densely populated areas. Furthermore, dampness and mould, and mould odour were risk factors for onset of asthma and rhinitis in northern Europe. In conclusion, indoor dampness and mould can be a risk factor for asthma and rhinitis in Sweden, China and northern Europe. Certain construction years (1961-1985), ETS, recent redecoration, new furniture, living in urban areas and exposure to traffic air pollution can be risk factors for asthma, rhinitis or respiratory infections. A high ventilation flow and daily cleaning at home can be protective.
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