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1.
  • Aspengren, Sara, 1977, et al. (författare)
  • Noradrenaline- and melatonin-mediated regulation of pigment aggregation in fish melanophores
  • 2003
  • Ingår i: Pigment Cell Research. - : Wiley. - 0893-5785. ; 16:1, s. 59-64
  • Tidskriftsartikel (refereegranskat)abstract
    • The effects of melatonin and noradrenaline (NA) on bi-directional melanosome transport were analysed in primary cultures of melanophores from the Atlantic cod. Both agents mediated rapid melanosome aggregation, and by using receptor antagonists, melatonin was found to bind to a melatonin receptor whereas NA binds to an α2-adrenoceptor. It has previously been stated that melatonin-mediated melanosome aggregation in Xenopus is coupled with tyrosine phosphorylation of a so far unidentified high molecular weight protein and we show that although acting through different receptors and through somewhat different downstream signalling events, tyrosine phosphorylation is of the utmost importance for melanosome aggregation mediated by both NA and melatonin in cod melanophores. Together with cyclic adenosine 3-phosphate-fluctuations, tyrosine phosphorylation functions as a switch signal for melanosome aggregation and dispersion in these cells.
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2.
  • Karah, Nabil, et al. (författare)
  • The acinetobacter baumannii website (ab-web) : a multidisciplinary knowledge hub, communication platform, and workspace
  • 2023
  • Ingår i: FEMS Microbes. - : Oxford University Press. - 2633-6685. ; 4
  • Forskningsöversikt (refereegranskat)abstract
    • Acinetobacter baumannii is a Gram-negative bacterium increasingly implicated in hospital-acquired infections and outbreaks. Effective prevention and control of such infections are commonly challenged by the frequent emergence of multidrug-resistant strains. Here we introduce Ab-web (https://www.acinetobacterbaumannii.no), the first online platform for sharing expertise on A. baumannii. Abweb is a species-centric knowledge hub, initially with 10 articles organized into two main sections, 'Overview' and 'Topics', and three themes, 'epidemiology', 'antibiotic resistance', and 'virulence'. The 'workspace' section provides a spot for colleagues to collaborate, build, and manage joint projects. Ab-web is a community-driven initiative amenable to constructive feedback and new ideas.
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