| 1. |
- Karlsson, Elinor K, et al.
(författare)
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Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B
- 2013
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Ingår i: Genome Biology. - : Springer Science and Business Media LLC. - 1465-6906 .- 1474-760X .- 1474-7596. ; 14:12
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Canine osteosarcoma is clinically nearly identical to the human disease, but is common and highly heritable, making genetic dissection feasible.RESULTS: Through genome-wide association analyses in three breeds (greyhounds, Rottweilers, and Irish wolfhounds), we identify 33 inherited risk loci explaining 55% to 85% of phenotype variance in each breed. The greyhound locus exhibiting the strongest association, located 150 kilobases upstream of the genes CDKN2A/B, is also the most rearranged locus in canine osteosarcoma tumors. The top germline candidate variant is found at a >90% frequency in Rottweilers and Irish wolfhounds, and alters an evolutionarily constrained element that we show has strong enhancer activity in human osteosarcoma cells. In all three breeds, osteosarcoma-associated loci and regions of reduced heterozygosity are enriched for genes in pathways connected to bone differentiation and growth. Several pathways, including one of genes regulated by miR124, are also enriched for somatic copy-number changes in tumors.CONCLUSIONS: Mapping a complex cancer in multiple dog breeds reveals a polygenic spectrum of germline risk factors pointing to specific pathways as drivers of disease.
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| 2. |
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| 3. |
- Abid, Fahim, et al.
(författare)
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Intermodulation due to interaction of photovoltaic inverter and electric vehicle at supraharmonic range
- 2016
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Ingår i: 2016 17th International Conference on Harmonics and Quality of Power. - Piscataway. NJ. - 9781509037926 ; , s. 685-690
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Konferensbidrag (refereegranskat)abstract
- Advent of power electronic switching is introducing more and more non-linear loads in the low voltage grid. Besides harmonic current generation in the frequency range below 2 kHz, these non-linear loads are also responsible for current emission in the range of 2 kHz to 150 kHz, commonly known as supraharmonic emission. Supraharmonic currents mainly flow between nearby appliances and heavily influence the overall emission of neighboring devices. This paper presents an analysis of supraharmonic interaction between a photovoltaic inverter and an electric vehicle. It has been noticed that intermodulation distortion arises as a result of interaction between different switching frequencies used by the devices. Later, additional household equipment were added to photovoltaic and electric vehicle to observe their effect on intermodulation distortion. All the measurements were conducted in a controlled laboratory environment imitating a domestic customer.
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| 4. |
- Ahmed, Kazi Main Uddin, 1989-, et al.
(författare)
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Electrical Energy Consumption Model of Internal Components in Data Centers
- 2019
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Ingår i: Proceedings of. - : IEEE.
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Konferensbidrag (refereegranskat)abstract
- In the context of modern information technology (IT) industry, cloud computing is gaining popularity for big data handling. Therefore, IT service providers like Google, Facebook and Amazon are expanding their technical resources by building data centers to improve the data processing and data storage facilities under cloud service pattern. However, data centers consume a large amount of electrical energy. In recent years, a lot of research has been done to reduce the electrical energy consumption of data centers by high performance computing. However, very few researchers have focused on the electrical energy consumption by the electrical components inside the data center. In this paper, a component based electrical energy consumption modelling approach is presented to identify the losses of different components as well as their interactions to the total electrical energy consumption of the data center. The electrical energy consumption models of servers and other components are presented as a function of server utilization.
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| 5. |
- Alvarez, Manuel, 1980-, et al.
(författare)
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A Capacity Mechanism Design for Distribution Network Expansion Planning
- 2018
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Ingår i: 2018 IEEE International Conference on Environment and Electrical Engineering and 2018 IEEE Industrial and Commercial Power Systems Europe (EEEIC / I&CPS Europe). - 9781538651865 - 9781538651872
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Konferensbidrag (refereegranskat)abstract
- Capacity remuneration mechanisms have been originally oriented to ensure availability and continuity of supply on the power generation pool. Equivalent generation-based capacity mechanisms could be implemented to enhance and prolong the usability of the distribution grid. In particular, such capacity mechanisms would provide an alternative to traditional expansion options leading to investment deferral. In this work, a distribution capacity mechanism to fit within a distribution network planning methodology will be proposed and discussed. The capacity mechanism will be outlined following similar guidelines as for the design of capacity mechanisms used in the energy only market. The result of the design is a volume based capacity auction for a capacity-constrained system, oriented to both the active and the reactive power provision.
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| 6. |
- Alvarez, Manuel, et al.
(författare)
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A Smart Distribution Toolbox for Distribution System Planning
- 2015
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Konferensbidrag (refereegranskat)abstract
- The distribution system planner should be able to coordinate smart grid solutions in order to find cost effective expansions plans. These plans should be able to deal with new added system uncertainties from renewable production and consumers while guaranteeing power quality and availability of supply. This paper proposes a structure for distribution systems planning oriented to help the planner in deciding how to make use of smart solutions for achieving the described task. Here, the concept of a system planning toolbox is introduced and supported with a review of relevant works implementing smart solutions. These are colligated in a way that the system planner can foresee what to expect with their combined implementation. Future developments in this subject should attempt to theorize a practical algorithm in an optimization and decision making context.
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| 7. |
- Alvarez Perez, Manuel Alejandro, 1980-, et al.
(författare)
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A Generic Storage Model Based on a Future Cost Piecewise-Linear Approximation
- 2019
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Ingår i: IEEE Transactions on Smart Grid. - : Institute of Electrical and Electronics Engineers (IEEE). - 1949-3053 .- 1949-3061. ; 10:1, s. 878-888
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Tidskriftsartikel (refereegranskat)abstract
- This work presents a generic storage model (GSM) inspired by the scheduling of hydraulic reservoirs. The model for steady state short-term (ST) operational studies interlaces with the long-term (LT) energy scheduling through a piecewise-linear Future Cost Function (FCF). Under the assumption that a Stochastic Dual Dynamic Programming (SDDP) approach has been used to solve the energy schedule for the LT, the FCF output from that study will be processed to obtain an equivalent marginal opportunity cost for the storage unit. The linear characteristic of a segment of the future cost function (FCF) will allow a linear modeling of the storage unit production cost. This formulation will help to coordinate the renewable resource along with storage facilities in order to find the optimal operation cost while meeting end-point conditions for the long-term plan of the energy storage. The generic model will be implemented to represent a battery storage and a pumped-hydro storage. A stochastic unit commitment (SUC) with the GSM will be formulated and tested to assess the day-ahead scheduling strategy of a Virtual Power Plant (VPP) facing uncertainties from production, consumption, and market prices.
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| 8. |
- Alvarez Perez, Manuel Alejandro, 1980-, et al.
(författare)
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A Hydro-Reservoir Generic Storage Model for Short-Term Hydrothermal Coordination
- 2017
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Ingår i: IEEE PES PowerTech Manchester 2017: towards and beyond sustainable energy systems, 2017. - Piscataway, NJ : Institute of Electrical and Electronics Engineers (IEEE). - 9781509042371
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Konferensbidrag (refereegranskat)abstract
- This work presents a linear solution for the short-term hydro-thermal scheduling problem linked to long-term conditions through a piecewise-linear Future Cost Function (FCF). Given end-point conditions to conform long-term water releases, and given actual reservoir conditions, a segment of a pre-built piecewise future cost function will be chosen. The linear characteristic of the FCF segment will allow a linear modeling of the hydro-power plant, in a similar fashion as a thermal unit with an equivalent marginal opportunity cost. A short-term hydro thermal coordination problem will be formulated considering parallel and cascaded hydro-reservoirs. Three study cases involving different reservoir configurations and scenarios will be computed to test the model. The results of this model mimics coherently the future-cost hydro-thermal coordination problem for the different configurations tested. Given similarities with other forms of energy storage, a new theoretical model for generic storage will be proposed and discussed.
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| 9. |
- Alvarez Perez, Manuel Alejandro, 1980-, et al.
(författare)
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Regulatory Matters Affecting Distribution Planning With Distributed Generation
- 2017
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Ingår i: CIRED - Open Access Proceedings Journal. - : Institute of Electrical and Electronics Engineers (IEEE). - 2515-0855. ; 2017:1, s. 2869-2873
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Tidskriftsartikel (refereegranskat)abstract
- Under the present European directive concerning common rules for the internal market in electricity, distribution companies are not allowed to own distributed generation (DG) but encouraged to include it as a planning option to defer investment in traditional grid reinforcements. Distribution system operators (DSOs) have used the provision of capacity contracted to DG as a viable alternative under current regulatory arrangements. Here, the topics bonding DSOs and DG owners under the present regulation will be explored and a planning structure that considers distribution capacity contracts as a planning option will be proposed. This will serve as a road map for DSOs to implement its preferred planning tools in an optimisation context, considering costs of investment, reliability, operation, and capacity provision while complying with current regulation.
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| 10. |
- Alvarez Perez, Manuel Alejandro, 1980-, et al.
(författare)
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Remuneration Assessment of a VPP Providing Distribution Capacity Services
- 2017
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Ingår i: IEEE PES PowerTech Manchester 2017. - Piscataway, NJ : Institute of Electrical and Electronics Engineers (IEEE). - 9781509042371
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Konferensbidrag (refereegranskat)abstract
- A Distribution System Operator (DSO) might consider a capacity contract as a planning alternative to defer grid investments. A Virtual Power Plant (VPP) might be able to provide such capacity and change its production as requested by the DSO. This article presents an assessment of the impact of this type of distribution capacity contract (DCC) on VPP's remuneration. This assessment is done by comparing the optimal production / bidding strategy which maximize its profit, under presence or absence of these contracts. The impact of intermittent generation and storage while evaluating these scenarios will be investigated as well. A stochastic unit commitment will be used to determine the VPP's strategy under uncertainties from wind power, load, market prices, and the requested power by the DSO. The model showed that the VPP involvement in distribution capacity contracts can improve its remuneration when certain types of Distributed Energy Resources (DER) are used to provide the service.
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